Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kim Doré"'
Autor:
Gema Lordén, Jacob M. Wozniak, Kim Doré, Lara E. Dozier, Chelsea Cates-Gatto, Gentry N. Patrick, David J. Gonzalez, Amanda J. Roberts, Rudolph E. Tanzi, Alexandra C. Newton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Mutations that enhance the activity of protein kinase C alpha (PKCα) are associated with Alzheimer’s Disease. Here, the authors report that the enhanced activity of one variant, PKCα M489V, is sufficient to rewire the brain phosphoproteome, drive
Externí odkaz:
https://doaj.org/article/f626c5ecba534cfcaa1608a36cecb5d0
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112170 (2014)
Little is known about the changes in protein interactions inside synapses during synaptic remodeling, as their live monitoring in spines has been limited. We used a FRET-FLIM approach in developing cultured rat hippocampal neurons expressing fluoresc
Externí odkaz:
https://doaj.org/article/2488b13cef8b40d58da0625582543786
Autor:
Gema Lordén, Jacob M. Wozniak, Kim Doré, Lara E. Dozier, Chelsea Cates-Gatto, Gentry N. Patrick, David J. Gonzalez, Amanda J. Roberts, Rudolph E. Tanzi, Alexandra C. Newton
Publikováno v:
Nature communications. 13(1)
Exquisitely tuned activity of protein kinase C (PKC) isozymes is essential to maintaining cellular homeostasis. Whereas loss-of-function mutations are generally associated with cancer, gain-of-function variants in one isozyme, PKCα, are associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af5421033528c14cf48ccd84dc57aa2
https://pubmed.ncbi.nlm.nih.gov/36418293
https://pubmed.ncbi.nlm.nih.gov/36418293
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The relative amount of AMPA receptors expressed at the surface of neurons can be measured using superecliptic pHluorin (SEP) labeling at their N-terminus. However, the high signal variability resulting from protein overexpression in neurons and the l
Externí odkaz:
https://doaj.org/article/7f6f8873f4864c3eb0cf7f19a2b94144
Autor:
Hoang-Anh Ho, Maurice Boissinot, Michel G. Bergeron, Geneviève Corbeil, Kim Doré, Denis Boudreau, Mario Leclerc
Publikováno v:
ACS Symposium Series ISBN: 9780841238305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcface25e4cc25349278dfbbe0020463
https://doi.org/10.1021/bk-2005-0888.ch027
https://doi.org/10.1021/bk-2005-0888.ch027
Publikováno v:
Journal of Fluorescence; Mar2006, Vol. 16 Issue 2, p259-265, 7p
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 8 (2016)
The NMDA receptor (R) participates in many important physiological and pathological processes. For example, its activation is required for both long-term potentiation (LTP) and long-term depression (LTD) of synaptic transmission, cellular models of l
Externí odkaz:
https://doaj.org/article/6247c0748a6a44cd9d5c20527232a002
Autor:
Kim Doré
Entre le laboratoire du chercheur et l’espace narratif du roman subsiste une volonté commune de révéler, d’organiser et de structurer les objets auxquels la pensée s’attache. Évidemment, alors que la science espère des résultats ou susci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f59d3f9f5c5a8faf383a90552d2e2d
https://id.erudit.org/iderudit/008486ar
https://id.erudit.org/iderudit/008486ar
Autor:
Antoine G. Godin, Laure Freland, Mikhail Sergeev, Paul W. Wiseman, Jody L. Swift, Yves De Koninck, Martin Beaulieu, Kim Doré
Publikováno v:
Biophysical Journal. (3):37a-38a
Recent evidence suggests that signaling responses elicited by G-protein coupled receptors (GPCRs) are more complex than first believed. For instance, stimulation of several GPCRs leads to the transactivation of receptor tyrosine kinase (RTK) signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0371356986f1d3ead85bb8b134534fd0