Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kim D. Mooiman"'
Publikováno v:
Cancer Treatment Reviews. 39:773-783
The use of complementary and alternative medicines (CAM) by cancer patients is increasing. Concomitant use of CAM and anticancer drugs could lead to serious safety issues in patients. CAM have the potential to cause pharmacokinetic interactions with
Autor:
Kim D. Mooiman, Roel F. Maas-Bakker, Jos H. Beijnen, Irma Meijerman, C. Lau, Jan H.M. Schellens
Publikováno v:
Journal of Ethnopharmacology. 149:543-549
Ethnopharmacological relevance Traditional Chinese Medicine (TCM) has become more popular among cancer patients in the Western world, who often use Chinese herbs as adjuvant therapy to reduce the adverse effects of conventional chemotherapy. However,
Autor:
Hilde Rosing, Irma Meijerman, Kim D. Mooiman, Roel F. Maas-Bakker, Jos H. Beijnen, Jan H.M. Schellens
Publikováno v:
Biomedical Chromatography. 27:1107-1116
Complementary and alternative medicines (CAM) can affect the pharmacokinetics of anticancer drugs by interacting with the metabolizing enzyme cytochrome P450 (CYP) 3A4. To evaluate changes in the activity of CYP3A4 in patients, levels of 1-hydroxymid
Autor:
Ed E. Moret, Jos H. Beijnen, Kim D. Mooiman, Jan H.M. Schellens, Roel F. Maas-Bakker, Irma Meijerman
Publikováno v:
Drug Metabolism and Disposition. 41:1494-1504
Because cancer is often treated with combination therapy, unexpected pharmacological effects can occur because of drug-drug interactions. Several drugs are able to cause upregulation or downregulation of drug transporters or cytochrome P450 enzymes,
Publikováno v:
The oncologist. 17(5)
The safety, tolerability, and efficacy of the mixture of botanical compounds known as LCS101 were evaluated in the prevention of chemotherapy-induced hematological toxicity in breast cancer patients in a prospective, controlled study.
Publikováno v:
The Oncologist. 17:740-741
Based on the results of a prospective, randomized, placebo-controlled study of Yaal-Hahoshen et al., [1] the authors concluded that the botanical mixture LCS101 prevented hematological complications in breast cancer patients undergoing anthracycline-
Publikováno v:
Cancer Research. 72:3791-3791
Introduction Many anticancer drugs, such as paclitaxel and erlotinib, are able to induce the expression of cytochrome P450 (CYP450) 3A4.1 Induction of intestinal and hepatic CYP3A4 can result in a decreased uptake and an increased metabolism of antic