Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kim D. Finley"'
Publikováno v:
Health Science Reports, Vol 4, Iss 2, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/d1190e38157f46569bc7cb4510eb6d5a
Autor:
Richard Dargusch, Devin Kepchia, Kim D. Finley, Pamela Maher, Antonio Currais, David Schubert
Publikováno v:
Aging (Albany NY)
Geroprotectors are compounds that slow the biological aging process in model organisms and may therefore extend healthy lifespan in humans. It is hypothesized that they do so by preserving the more youthful function of multiple organ systems. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0b60dc05fcd6e44cc7c0a199b55656
https://doi.org/10.18632/aging.202631
https://doi.org/10.18632/aging.202631
Autor:
Eric P Ratliff, Roxanne W Kotzebue, Brandon Molina, Ruth E Mauntz, Arysa Gonzalez, Ayeh Barekat, Nadja El-Mecharrafie, Shannon Garza, Michael A Gurney, Madhulika Achal, Phyllis-Jean Linton, Greg L Harris, Kim D Finley
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164239 (2016)
The autophagy pathway is critical for the long-term homeostasis of cells and adult organisms and is often activated during periods of stress. Reduced pathway efficacy plays a central role in several progressive neurological disorders that are associa
Externí odkaz:
https://doaj.org/article/90935df0fad34007ba2dadd93907a089
Autor:
Eric P Ratliff, Ruth E Mauntz, Roxanne W Kotzebue, Arysa Gonzalez, Madhulika Achal, Ayeh Barekat, Kaelyn A Finley, Jonathan M Sparhawk, James E Robinson, Deron R Herr, Greg L Harris, William J Joiner, Kim D Finley
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132768 (2015)
Multiple neurological disorders are characterized by the abnormal accumulation of protein aggregates and the progressive impairment of complex behaviors. Our Drosophila studies demonstrate that middle-aged wild-type flies (WT, ~4-weeks) exhibit a mar
Externí odkaz:
https://doaj.org/article/155c9470bb3143b9b52e5be86a9e0f53
Publikováno v:
Health Science Reports
Health Science Reports, Vol 4, Iss 2, Pp n/a-n/a (2021)
Health Science Reports, Vol 4, Iss 2, Pp n/a-n/a (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced2148bc8ef6ceb34e1b0cfe082fcd9
http://europepmc.org/articles/PMC8133833
http://europepmc.org/articles/PMC8133833
Autor:
Erica M. Forsberg, Jessica Mastroianni, Kim D. Finley, Brandon Molina, Ema Suarez, Brijinder Soni
Publikováno v:
Cells, Vol 10, Iss 900, p 900 (2021)
Cells
Volume 10
Issue 4
Cells
Volume 10
Issue 4
Drosophila are widely used to study neural development, immunity, and inflammatory pathways and processes associated with the gut–brain axis. Here, we examine the response of adult Drosophila given an inactive bacteriologic (IAB
proprietary ly
proprietary ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c00e3843f506682b885004ec8fe21bf
https://pubmed.ncbi.nlm.nih.gov/33919883
https://pubmed.ncbi.nlm.nih.gov/33919883
Autor:
Stanley M Walls, Steve J Attle, Gregory B Brulte, Marlena L Walls, Kim D Finley, Dale A Chatfield, Deron R Herr, Greg L Harris
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003970 (2013)
Obesity is defined by excessive lipid accumulation. However, the active mechanistic roles that lipids play in its progression are not understood. Accumulation of ceramide, the metabolic hub of sphingolipid metabolism, has been associated with metabol
Externí odkaz:
https://doaj.org/article/b13ae1338c014eddb9c88a7abe73a008
Autor:
David Schubert, Joshua Goldberg, Kim D. Finley, Michael Petrascheck, Pamela Maher, Antonio Currais
Publikováno v:
Trends in pharmacological sciences. 39(12)
Geroprotectors are compounds that slow the rate of biological aging and therefore may reduce the incidence of age-associated diseases such as Alzheimer's disease (AD). However, few have therapeutic efficacy in mammalian AD models. Here we describe th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc958bcc76a8a6ca05d3633bdee1847
https://pubmed.ncbi.nlm.nih.gov/30446211
https://pubmed.ncbi.nlm.nih.gov/30446211
Autor:
Eric P. Ratliff, Pau B. Esparza-Moltó, Marguerite Prior, Michael Petrascheck, David Schubert, Wolfgang H. Fischer, Pamela Maher, Kim D. Finley, Richard Dargusch, Daniel Daugherty, José M. Cuezva, Antonio Currais, Joshua Goldberg, Chandramouli Chiruta
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Aging Cell
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Aging Cell
Biblos-e Archivo. Repositorio Institucional de la UAM
Aging is a major driving force underlying dementia, such as that caused by Alzheimer's disease (AD). While the idea of targeting aging as a therapeutic strategy is not new, it remains unclear how closely aging and age-associated diseases are coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f8a4f5a37c170c314d42be2ca9cc23
http://hdl.handle.net/10261/182040
http://hdl.handle.net/10261/182040
Publikováno v:
Autophagy. 12(11)
Drosophila models have been successfully used to identify many genetic components that affect neurodegenerative disorders. Recently, there has been a growing interest in identifying innate and environmental factors that influence the individual outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39820014ef21a9b25779a946441d987
https://pubmed.ncbi.nlm.nih.gov/27560096
https://pubmed.ncbi.nlm.nih.gov/27560096