Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kim C M, van der Elst"'
Autor:
Erin H. Smeijsters, Kim C. M. van der Elst, Amy Visch, Camiel Göbel, Floris C. Loeff, Theo Rispens, Alwin D. R. Huitema, Matthijs van Luin, Mohsin El Amrani
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1477 (2023)
Monoclonal antibodies (mAbs), such as infliximab, are important treatment options for different diseases. Immunogenicity is a major risk, resulting in anti-drug antibodies (ADAs), being associated with adverse events and loss of response, influencing
Externí odkaz:
https://doaj.org/article/17e81377605e42de912eb2b322fe36bf
Autor:
Gaël Vermeersch, Lies Laenen, Géraldine Lens, Kim C. M. van der Elst, Dietmar Rudolf Thal, Sander Jentjens, Philippe Demaerel, Tine Van Nieuwenhuyse, Elke Wollants, Nancy Boeckx, Nicolas Verhaert, Benedicte Dubois, Frank J. M. Kuppeveld, F. J. Sherida H. Woei‐A‐Jin
Publikováno v:
European Journal of Neurology. 29:3117-3123
Enterovirus infections pose a serious threat for patients with humoral deficiencies and may be lethal, whilst the efficacy of proposed treatment options such as corticosteroids, intravenous immunoglobulins and fluoxetine remains debated.Viral clearan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7971024bde1d4bef3d5b13bc5d206726
https://doi.org/10.1111/ene.15478
https://doi.org/10.1111/ene.15478
Autor:
Linde Dekker, Friso G. Calkoen, Yilin Jiang, Hilly Blok, Saskia R. Veldkamp, Coco De Koning, Maike Spoon, Rick Admiraal, Peter Hoogerbrugge, Britta Vormoor, H. Josef Vormoor, Henk Visscher, Marc Bierings, Marieke Van Der Vlugt, Harm Van Tinteren, A. Laura Nijstad, Alwin D. R. Huitema, Kim C. M. Van Der Elst, Rob Pieters, Caroline A. Lindemans, Stefan Nierkens
Publikováno v:
Blood Advances. 6:1969-1976
The addition of fludarabine to cyclophosphamide as a lymphodepleting regimen prior to CD19 chimeric antigen receptor (CAR) T-cell therapy significantly improved outcomes in patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7908be72146f2f9270c912a748b9328b
https://doi.org/10.1182/bloodadvances.2021006700
https://doi.org/10.1182/bloodadvances.2021006700
Autor:
Eline H. Groenland, Indranil Dasgupta, Frank L. J. Visseren, Kim C. M. van der Elst, Nathan Lorde, Alexander J. Lawson, Michiel L. Bots, Wilko Spiering
Publikováno v:
Blood pressure. 31(1)
Purpose\ud Chemical adherence testing is a reliable method to assess adherence to antihypertensive drugs. However, it is expensive and has limited availability in clinical practice. To reduce the number and costs of chemical adherence tests, we aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62db7acd312b1cb7cdca5bcffd85e6a4
https://pubmed.ncbi.nlm.nih.gov/35899383
https://pubmed.ncbi.nlm.nih.gov/35899383
Autor:
Kim C M van der Elst, Michiel L. Bots, Monique E. A. M. van Kleef, Eline H. Groenland, Frank L.J. Visseren, Wilko Spiering
Publikováno v:
Hypertension. 77:85-93
Biochemical drug screening by liquid chromatography-tandem mass spectrometry in plasma is an accurate method for the quantification of plasma concentrations of antihypertensive medications in patients with hypertension. Trough concentrations could po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1700bc39bea2683457a0856ca49482c8
https://doi.org/10.1161/hypertensionaha.120.16061
https://doi.org/10.1161/hypertensionaha.120.16061
Autor:
Jan G. Zijlstra, Anne-Grete Märtson, Michael Neely, Jos G. W. Kosterink, Tjip S. van der Werf, Albertus Beishuizen, Jan-Willem C. Alffenaar, Kim C M van der Elst, Anette Veringa
Publikováno v:
Antimicrobial Agents and Chemotherapy, 64(9):ARTN e00905-20. AMER SOC MICROBIOLOGY
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy
The objective of this study was to develop a population pharmacokinetic model and to determine a dosing regimen for caspofungin in critically ill patients. Nine blood samples were drawn per dosing occasion. Fifteen patients with (suspected) invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a877418808747ef542bf40fe512db0f8
https://hdl.handle.net/11370/6c344d14-db20-4051-acef-898b548164c6
https://hdl.handle.net/11370/6c344d14-db20-4051-acef-898b548164c6
Publikováno v:
Journal of Chromatography A. 1665:462840
Next generation human therapeutic monoclonal antibodies (t-mAbs) are harder to quantify with the widely used bottom-up tryptic digestion method. Due to their homology with endogenous immunoglobulins, there is a lack of unique and stable 'signature' p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9830cc3e7a36a57a1d14472cc8d8a8
https://doi.org/10.1016/j.chroma.2022.462840
https://doi.org/10.1016/j.chroma.2022.462840
Autor:
Britta Vormoor, Maike Spoon, A. Laura Nijstad, Josef Vormoor, Rob Pieters, Peter M. Hoogerbrugge, Marc Bierings, Kim C M van der Elst, Marieke Van Der Vlugt, Harm van Tinteren, Linde Dekker, Henk Visscher, Alwin D. R. Huitema, Stefan Nierkens, F.G.J. Calkoen, C. Michel Zwaan, Hilly Blok, Rick Admiraal, Yilin Jiang, Caroline A. Lindemans
Publikováno v:
Blood. 138:3871-3871
The addition of fludarabine to cyclophosphamide as lymphodepleting regimen prior to adoptive transfer of CD19 chimeric antigen receptor (CAR) T cells significantly improves CAR T cell expansion and correlates with longer B cell aplasia and a decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a390fcfeb1933e81e6c15e85386d1ac
https://doi.org/10.1182/blood-2021-146450
https://doi.org/10.1182/blood-2021-146450
Autor:
Elior Peles, Martien J H Kas, Ricardo Scott, Hilgo Bruining, Lynette Lim, Nathalie Dehorter, Oscar Marín, Giorgia Bartolini, Sung Eun Bae, Kim C M van der Elst, Alberto Sanchez-Aguilera
Publikováno v:
Cerebral Cortex, 29(2), 586. Oxford University Press
Scott, R, Sanchez Aguilera, A, van Elst, K, Lim, L, Dehorter, N, Bae, S E, Bartolini, G, Peles, E, Kas, M J H, Bruining, H & Marin, O 2017, ' Loss of Cntnap2 causes axonal excitability deficits, developmental delay in cortical myelination, and abnormal stereotyped motor behaviour ', Cerebral Cortex, vol. 29, no. 2, pp. 586-597 . https://doi.org/10.1093/cercor/bhx341
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cerebral Cortex, 29(2). Oxford University Press
Scott, R, Sanchez Aguilera, A, van Elst, K, Lim, L, Dehorter, N, Bae, S E, Bartolini, G, Peles, E, Kas, M J H, Bruining, H & Marin, O 2017, ' Loss of Cntnap2 causes axonal excitability deficits, developmental delay in cortical myelination, and abnormal stereotyped motor behaviour ', Cerebral Cortex, vol. 29, no. 2, pp. 586-597 . https://doi.org/10.1093/cercor/bhx341
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cerebral Cortex, 29(2). Oxford University Press
Contactin-associated protein-like 2 (Caspr2) is found at the nodes of Ranvier and has been associated with physiological properties of white matter conductivity. Genetic variation in CNTNAP2, the gene encoding Caspr2, has been linked to several neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a520deffd07fae7cf4c34329315d86cc
https://dspace.library.uu.nl/handle/1874/387904
https://dspace.library.uu.nl/handle/1874/387904
Autor:
Tania Mudrikova, Erin H Smeijsters, Bastiaan Tgm Sallevelt, Kim C M van der Elst, Toine C. G. Egberts
Publikováno v:
Clinical Infection in Practice, Vol 7, Iss, Pp 100046-(2020)
Background Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing. Inconsistency in clinical guideline recommendations a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f92683c2e6c65b9af873eea167ae1d
https://doi.org/10.1016/j.clinpr.2020.100046
https://doi.org/10.1016/j.clinpr.2020.100046