Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Kim A Woodrow"'
Publikováno v:
Frontiers in Oral Health, Vol 2 (2022)
The oral mucosa contains distinct tissue sites with immune niches capable of either immunogenic or tolerogenic responses. However, immune cell compositions within oral mucosal tissues at homeostasis have not been well-characterized in human relevant
Externí odkaz:
https://doaj.org/article/91a703472a2844dab1cebce8c2939547
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 582-590 (2017)
Composite delivery systems where drugs are electrospun in different layers and vary the drug stacking-order are posited to affect bioavailability. We evaluated how the formulation characteristics of both burst- and sustained-release electrospun fiber
Externí odkaz:
https://doaj.org/article/1b4d0d81de814e6c9992a170244b620b
Publikováno v:
Advanced Drug Delivery Reviews. 198:114860
Publikováno v:
ACS biomaterials scienceengineering. 8(7)
Medical technology that blocks the fallopian tubes nonsurgically could increase access to permanent contraception and address current unmet needs in family planning. To achieve total occlusion of the fallopian tube via scar tissue formation, acute tr
Autor:
Shijie Cao, Ian T. Suydam, Wilma E Afunugo, Kim A. Woodrow, Alaina M. Bever, Yonghou Jiang, Rachel Creighton, Mikaela E Ebner
Publikováno v:
ACS Biomater Sci Eng
Polymeric nanocarriers have been extensively used to improve the delivery of hydrophobic drugs, but often provide low encapsulation efficiency and percent loading for hydrophilic compounds. In particular, insufficient loading of hydrophilic antiretro
Autor:
Jamie L. Hernandez, Kim A. Woodrow
Publikováno v:
Adv Healthc Mater
Porosity is an important material feature commonly employed in implants and tissue scaffolds. The presence of material voids permits the infiltration of cells, mechanical compliance, and outward diffusion of pharmaceutical agents. Various studies hav
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61416 (2013)
The use of drug combinations has revolutionized the treatment of HIV but there is no equivalent combination product that exists for prevention, particularly for topical HIV prevention. Strategies to combine chemically incompatible agents may facilita
Externí odkaz:
https://doaj.org/article/cbed63ce1e434f27bf87a8a51c66b2ed
Autor:
Florian Hladik, Shijie Cao, Jae Hyung Park, Sean M. Hughes, Hannah Frizzell, Kim A. Woodrow, David M. Koelle, Hangyu Zhang
Publikováno v:
J Control Release
Dendritic cells (DCs) play a critical role in shaping adaptive immunity. Systemic transfer of DCs by intravenous injection has been widely investigated to inform the development of immunogenic DCs for use as cellular therapies. Adoptive transfer of D
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49792 (2012)
Multipurpose prevention technologies (MPTs) that simultaneously prevent sexually transmitted infections (STIs) and unintended pregnancy are a global health priority. Combining chemical and physical barriers offers the greatest potential to design eff
Externí odkaz:
https://doaj.org/article/ed26f89319814629b60d387a24e96dc3
Autor:
Shijie Cao, Yonghou Jiang, Florian Hladik, Claire N. Levy, Kim A. Woodrow, Hangyu Zhang, Sean M. Hughes
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:1177-1188
Monoclonal antibodies and peptides are conjugated to the surface of nanocarriers (NCs) for targeting purposes in numerous applications. However, targeting efficacy may vary with their specificity, affinity, or avidity when linked to NCs. The physicoc