Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kim A, Heidenreich"'
Autor:
Santiago E. Farias, Mireille Basselin, Lisa Chang, Kim A. Heidenreich, Stanley I. Rapoport, Robert C. Murphy
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 9, Pp 1990-2000 (2008)
Inflammatory lipid mediators derived from arachidonic acid (AA) and docosahexaenoic acid (DHA) modify the pathophysiology of brain ischemia. The goal of this work was to investigate the formation of eicosanoids and docosanoids generated from AA and D
Externí odkaz:
https://doaj.org/article/38eaa38577f14109838e71781dcc26b1
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 71:1211-1218
Enzymatic and nonenzymatic oxidation of polyunsaturated fatty acids leads to the formation of biologically active products known as lipid mediators. In the brain, lipid mediators play an important role in supporting homeostasis and normal function. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145343d53b42ef954d77ebab98fd57a5
https://doi.org/10.1097/ta.0b013e3182092c62
https://doi.org/10.1097/ta.0b013e3182092c62
Publikováno v:
Neuroscience Letters. 488:112-117
Restoration of autophagy represents a potential therapeutic target for neurodegenerative disorders, but factors that regulate autophagic flux are largely unknown. When deprived of trophic factors, cultured Purkinje neurons die by an autophagy associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b118884287839b1827ec747a7a473b
https://doi.org/10.1016/j.neulet.2010.09.018
https://doi.org/10.1016/j.neulet.2010.09.018
Publikováno v:
Journal of Biological Chemistry. 284:20398-20407
Continuous macroautophagic activity is critical for the maintenance of neuronal homeostasis; however, unchecked or dysregulated autophagy can lead to cell death. Cultured Purkinje neurons die by an autophagy-associated cell death mechanism when depri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10fcb96be60e8c5b016c471ba85f6d4
https://doi.org/10.1074/jbc.m109.011791
https://doi.org/10.1074/jbc.m109.011791
Autor:
Kim A. Heidenreich, Stanley I. Rapoport, Santiago E. Farias, Robert C. Murphy, Mireille Basselin, Lisa Chang
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 9, Pp 1990-2000 (2008)
Inflammatory lipid mediators derived from arachidonic acid (AA) and docosahexaenoic acid (DHA) modify the pathophysiology of brain ischemia. The goal of this work was to investigate the formation of eicosanoids and docosanoids generated from AA and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720aecfc66f68d92c04f7f150af3aa00
http://www.sciencedirect.com/science/article/pii/S0022227520346678
http://www.sciencedirect.com/science/article/pii/S0022227520346678
Autor:
E.A. Esch, Daniel A. Linseman, T.A. Precht, Kim A. Heidenreich, Ron J. Bouchard, J.L. Brewster, F.A. Loucks
Publikováno v:
Molecular and Cellular Neuroscience. 32:242-253
Loss of trophic or activity-dependent survival signals is commonly recognized as a stimulus for neuronal apoptosis and may play a significant role in neurodegeneration. Recent data have also implicated endoplasmic reticulum (ER) stress as an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfd8e8bd1a9aa9bd0e4764d4dcad0f1
https://doi.org/10.1016/j.mcn.2006.04.006
https://doi.org/10.1016/j.mcn.2006.04.006
Autor:
Terry G. Unterman, David R. Powell, Roberta Franks, Wenwei Zhang, Robert V. Farese, Donna B. Stolz, Sandip Patil, Seung Hoi Koo, Mini P. Sajan, Angelos Klotsas, Ryan Matika, Jamie Le, Xiangshan Xiao, Patrick Tso, Shaodong Guo, Balwant Chauhan, Kim A. Heidenreich, Marc Montminy
Publikováno v:
Journal of Biological Chemistry. 281:10105-10117
FoxO transcription factors are important targets of insulin action. To better understand the role of FoxO proteins in the liver, we created transgenic mice expressing constitutively active FoxO1 in the liver using the α1-antitrypsin promoter. Fastin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33bffad64b6e7a490f13cda86576fcb4
https://doi.org/10.1074/jbc.m600272200
https://doi.org/10.1074/jbc.m600272200
Autor:
Kim A. Heidenreich
Publikováno v:
Annals of the New York Academy of Sciences. 991:237-250
Chronic neurodegenerative diseases, including Parkinson's disease, are characterized by a selective loss of specific subsets of neuronal populations over a period of years or even decades. While the underlying causes of the various neurodegenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66784dca0cd0135be155d3d88a1a0e12
https://doi.org/10.1111/j.1749-6632.2003.tb07480.x
https://doi.org/10.1111/j.1749-6632.2003.tb07480.x
Autor:
Kenneth L. Tyler, Ron J. Bouchard, Holger Barth, Kim A. Heidenreich, Reid A. Phelps, F. Alexandra Loucks, Daniel A. Linseman, Hiroshi Udo, Shoshona S. Le, Eric R. Kandel, Klaus Aktories, Sarah M. Richardson-Burns
Publikováno v:
Journal of Neurochemistry. 94:1025-1039
Rho GTPases are key transducers of integrin/extracellular matrix and growth factor signaling. Although integrin-mediated adhesion and trophic support suppress neuronal apoptosis, the role of Rho GTPases in neuronal survival is unclear. Here, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::280010ae8b1bac82573d9d71943f862b
https://doi.org/10.1111/j.1471-4159.2005.03252.x
https://doi.org/10.1111/j.1471-4159.2005.03252.x