Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Kim Boekelheide"'
Autor:
Hui Li, Haitham Seada, Samantha Madnick, He Zhao, Zhaozeng Chen, Fengcheng Li, Feng Zhu, Susan Hall, Kim Boekelheide
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Endocrine-disrupting chemicals (EDCs) pose a significant threat to human well-being and the ecosystem. However, in managing the many thousands of uncharacterized chemical entities, the high-throughput screening of EDCs using relevant biologi
Externí odkaz:
https://doaj.org/article/f4ac0e30b8f242aebab710c68c6e7c52
Autor:
Karl T. Kelsey, Matthew Rytel, Edward Dere, Rondi Butler, Melissa Eliot, Susan M. Huse, E. Andres Houseman, Devin C. Koestler, Kim Boekelheide
Publikováno v:
Environmental Health, Vol 18, Iss 1, Pp 1-11 (2019)
Abstract Background Exposure to the herbicide Agent Orange during the Vietnam War was widespread and is associated with numerous adverse health outcomes. A continuing concern of veterans is the possibility that exposure to the dioxin-containing herbi
Externí odkaz:
https://doaj.org/article/9710d39898574969ac92632bcf2b5eed
Autor:
Enrica Bianchi, Kim Boekelheide, Mark Sigman, Joseph M Braun, Melissa Eliot, Susan J Hall, Edward Dere, Kathleen Hwang
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216584 (2019)
Semen analysis is one of the standard diagnostic tools currently used to assess male infertility and reproductive toxicity. However, semen analysis has a limited ability to separate fertile from infertile populations. Additional methods to detect imp
Externí odkaz:
https://doaj.org/article/f5744a9d6d4846a4a89e5d3a61df56ec
Autor:
Pranita K. Kabadi, Marguerite M. Vantangoli, April L. Rodd, Elizabeth Leary, Samantha J. Madnick, Jeffrey R. Morgan, Agnes Kane, Kim Boekelheide
Publikováno v:
BioTechniques, Vol 59, Iss 5, Pp 279-286 (2015)
Three-dimensional (3-D) in vitro platforms have been shown to closely recapitulate human physiology when compared with conventional two-dimensional (2-D) in vitro or in vivo animal model systems. This confers a substantial advantage in evaluating dis
Externí odkaz:
https://doaj.org/article/7ce370630ed5493cbf62d5256b42e802
Publikováno v:
Toxicology in Vitro. 91:105624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e2a5a74bc6e65d5cf110edb9c76dad
https://doi.org/10.1016/j.tiv.2023.105624
https://doi.org/10.1016/j.tiv.2023.105624
Autor:
Susan J. Hall, Kathleen Hwang, Enrica Bianchi, Hui Li, Mark Sigman, Angela R Stermer, Kim Boekelheide, Timothy Nolan
Publikováno v:
Reproductive Toxicology. 104:44-51
Assessing male reproductive toxicity of environmental and therapeutic agents relies on the histopathology of the testis and epididymis in a pre-clinical setting. Animal histopathology poorly correlates with human sperm parameters, and none of these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4654fe318f9a1e6100651c8afc7a63a
https://doi.org/10.1016/j.reprotox.2021.06.012
https://doi.org/10.1016/j.reprotox.2021.06.012
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177995 (2017)
Cryptorchidism or undescended testis (UDT) is a common congenital abnormality associated with increased risk for developing male infertility and testicular cancer. This study elucidated the effects of endogenous ghrelin or growth hormone secretagogue
Externí odkaz:
https://doaj.org/article/ab231fd3dfa843e7847b00324aeb2c21
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157997 (2016)
The development of three-dimensional (3D) cultures is increasing, as they are able to provide the utility of in vitro models and the strength of testing in physiologically relevant systems. When cultured in a scaffold-free agarose hydrogel system, MC
Externí odkaz:
https://doaj.org/article/5818c81a9d834455b4fe16f79c245769
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153968 (2016)
Post-operative adhesions are a critical problem in pelvic and abdominal surgery despite a multitude of studies dedicated to finding modalities to prevent their occurrence. Ghrelin administration promotes an anti-fibrotic response in a surgical mouse
Externí odkaz:
https://doaj.org/article/5b639a244a1f4ad293a93f33c64a4c77
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135426 (2015)
Three-dimensional (3D) cultures are increasing in use because of their ability to represent in vivo human physiology when compared to monolayer two-dimensional (2D) cultures. When grown in 3D using scaffold-free agarose hydrogels, MCF-7 human breast
Externí odkaz:
https://doaj.org/article/fbc11162452d4162a3d3d816d5643258