Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kim, Vanuytsel"'
Autor:
Dmitry A. Kretov, Leighton Folkes, Alexandra Mora-Martin, Isha A. Walawalkar, Imrat, Noreen Syedah, Kim Vanuytsel, Simon Moxon, George J. Murphy, Daniel Cifuentes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Differentiation of stem and progenitor cells is a highly regulated process that involves the coordinated action of multiple layers of regulation. Here we show how the post-transcriptional regulatory layer instructs the level of chromatin reg
Externí odkaz:
https://doaj.org/article/12c9809215524e7283c8840d491bb1be
Autor:
Wei Wen Teo, Xinang Cao, Chan-Shuo Wu, Hong Kee Tan, Qiling Zhou, Chong Gao, Kim Vanuytsel, Sara S. Kumar, George J. Murphy, Henry Yang, Li Chai, Daniel G. Tenen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Identification of a long non-coding RNA LEVER, that inhibits the Polycomb Repressive Complex 2 (PRC2) and controls nearby embryonic form of beta-globin gene, provides additional evidence for PRC2-RNA functional interaction.
Externí odkaz:
https://doaj.org/article/c0033e53f61b43739e86a5b844cef74f
Autor:
Kim Vanuytsel, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Zhe Wang, Wilfredo F. Garcia-Beltran, Vladimir Vrbanac, Dylan Parsons, Evan C. Lam, Taylor M. Matte, Todd W. Dowrey, Sara S. Kumar, Mengze Li, Feiya Wang, Anthony K. Yeung, Gustavo Mostoslavsky, Ruben Dries, Joshua D. Campbell, Anna C. Belkina, Alejandro B. Balazs, George J. Murphy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
During human embryonic development, haematopoietic stem cells of the foetal liver undergo expansion, while retaining engraftment capacity. Here the authors apply CITE-seq to profile single cells from a human foetal liver, identifying a molecular sign
Externí odkaz:
https://doaj.org/article/cac11a57fa10405ca22f6fddb6df2365
Autor:
Darcy E. Wagner, Laertis Ikonomou, Sarah E. Gilpin, Chelsea M. Magin, Fernanda Cruz, Allison Greaney, Mattias Magnusson, Ya-Wen Chen, Brian Davis, Kim Vanuytsel, Sara Rolandsson Enes, Anna Krasnodembskaya, Mareike Lehmann, Gunilla Westergren-Thorsson, John Stegmayr, Hani N. Alsafadi, Evan T. Hoffman, Daniel J. Weiss, Amy L. Ryan
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
A workshop entitled “Stem Cells, Cell Therapies and Bioengineering in Lung Biology and Diseases” was hosted by the University of Vermont Larner College of Medicine in collaboration with the National Heart, Lung and Blood Institute, the Alpha-1 Fo
Externí odkaz:
https://doaj.org/article/7031ec1f2c5f467387a6307044f71bce
Autor:
Richard M. Giadone, Aditya Mithal, Gregory J. Miller, Taylor M. Matte, Anthony K. Yeung, Todd W. Dowrey, Rhiannon B. Werder, Nancy S. Miller, Christopher D. Andry, Kim Vanuytsel, George J. Murphy
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100102- (2020)
Summary: The protocols herein outline the use of qRT-PCR to detect the presence of SARS-CoV-2 genomic RNA in patient samples. In order to cope with potential fluctuations in supply chain and testing demands and to enable expedient adaptation of reage
Externí odkaz:
https://doaj.org/article/3349c7abf4194e76929334350de84a55
Autor:
Kim Vanuytsel, Qing Cai, Satish Khurana, Swati Shetty, Joris R. Vermeesch, Laura Ordovas, Catherine M. Verfaillie
Publikováno v:
Stem Cell Research, Vol 44, Iss , Pp - (2020)
Externí odkaz:
https://doaj.org/article/0296abf410e34c1c8c776f48ee19d332
Autor:
Kim Vanuytsel, Taylor Matte, Amy Leung, Zaw Htut Naing, Tasha Morrison, David H.K. Chui, Martin H. Steinberg, George J. Murphy
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1998-2011 (2018)
Abstract: Robust β-globin expression in erythroid cells derived from induced pluripotent stem cells (iPSCs) increases the resolution with which red blood cell disorders such as sickle cell disease and β thalassemia can be modeled in vitro. To bette
Externí odkaz:
https://doaj.org/article/90f65c6905b545d187d63ae96104ade0
Autor:
Seonmi Park, Andreia Gianotti-Sommer, Francisco Javier Molina-Estevez, Kim Vanuytsel, Nick Skvir, Amy Leung, Sarah S. Rozelle, Elmutaz Mohammed Shaikho, Isabelle Weir, Zhihua Jiang, Hong-Yuan Luo, David H.K. Chui, Maria Stella Figueiredo, Abdulraham Alsultan, Amein Al-Ali, Paola Sebastiani, Martin H. Steinberg, Gustavo Mostoslavsky, George J. Murphy
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1076-1085 (2017)
Summary: Sickle cell anemia affects millions of people worldwide and is an emerging global health burden. As part of a large NIH-funded NextGen Consortium, we generated a diverse, comprehensive, and fully characterized library of sickle-cell-disease-
Externí odkaz:
https://doaj.org/article/52d22f01919b4214b5dcc432e367860c
Autor:
Laura Ordovás, Ruben Boon, Mariaelena Pistoni, Yemiao Chen, Esther Wolfs, Wenting Guo, Rangarajan Sambathkumar, Sylwia Bobis-Wozowicz, Nicky Helsen, Jolien Vanhove, Pieter Berckmans, Qing Cai, Kim Vanuytsel, Kristel Eggermont, Veerle Vanslembrouck, Béla Z. Schmidt, Susanna Raitano, Ludo Van Den Bosch, Yaakov Nahmias, Toni Cathomen, Tom Struys, Catherine M. Verfaillie
Publikováno v:
Stem Cell Reports, Vol 10, Iss 2, Pp 673- (2018)
Externí odkaz:
https://doaj.org/article/93ada59455364727a50a5205739b2eef
Autor:
Laura Ordovás, Ruben Boon, Mariaelena Pistoni, Yemiao Chen, Esther Wolfs, Wenting Guo, Rangarajan Sambathkumar, Sylwia Bobis-Wozowicz, Nicky Helsen, Jolien Vanhove, Pieter Berckmans, Qing Cai, Kim Vanuytsel, Kristel Eggermont, Veerle Vanslembrouck, Béla Z. Schmidt, Susanna Raitano, Ludo Van Den Bosch, Yaakov Nahmias, Toni Cathomen, Tom Struys, Catherine M. Verfaillie
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 918-931 (2015)
Tools for rapid and efficient transgenesis in “safe harbor” loci in an isogenic context remain important to exploit the possibilities of human pluripotent stem cells (hPSCs). We created hPSC master cell lines suitable for FLPe recombinase-mediate
Externí odkaz:
https://doaj.org/article/104293e2640a470085393893e506221e