Discovery of CC Chemokine Receptor-3 (CCR3) Antagonists with Picomolar Potency

Autor: Lucca, G. V. De, Kim, U. T., Vargo, B. J., Duncia, J. V., Santella, J. B., III, Gardner, D. S., Zheng, C., Liauw, A., Wang, Z., Emmett, G., Wacker, D. A., Welch, P. K., Covington, M., Stowell, N. C., Wadman, E. A., Das, A. M., Davies, P., Yeleswaram, S., Graden, D. M., Solomon, K. A., Newton, R. C., Trainor, G. L., Decicco, C. P., Ko, S. S.

Publikováno v: Journal of Medicinal Chemistry; March 2005, Vol. 48 Issue: 6 p2194-2211, 18p

Nonsymmetric P2/P2‘ Cyclic Urea HIV Protease Inhibitors. Structure−Activity Relationship, Bioavailability, and Resistance Profile of Monoindazole-Substituted P2 Analogues

Autor: Lucca, G. V. De, Kim, U. T., Liang, J., Cordova, B., Klabe, R. M., Garber, S., Bacheler, L. T., Lam, G. N., Wright, M. R., Logue, K. A., Erickson-Viitanen, S., Ko, S. S., Trainor, G. L.

Publikováno v: Journal of Medicinal Chemistry; June 18, 1998, Vol. 41 Issue: 13 p2411-2423, 13p

ChemInform Abstract: Synthesis of Phospholipid Headgroups via Nucleophilic Ring Opening of 1,3,2-Dioxaphospholanes.

Autor: KIM, U. T., HAJDU, J.

Publikováno v: ChemInform; Apr1993, Vol. 24 Issue 17, pno-no, 1p

Nonsymmetric P2/P2' cyclic urea HIV protease inhibitors. Structure-activity relationship, bioavailability, and resistance profile of monoindazole-substituted P2 analogues.

Autor: De Lucca GV; Dupont Merck Pharmaceutical Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, USA. George.V.DeLucca@usa.dupont.com, Kim UT, Liang J, Cordova B, Klabe RM, Garber S, Bacheler LT, Lam GN, Wright MR, Logue KA, Erickson-Viitanen S, Ko SS, Trainor GL

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1998 Jun 18; Vol. 41 (13), pp. 2411-23.