Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Kim, Holmstrøm"'
Autor:
Boye Schnack Nielsen, Natasha Helleberg Madsen, Jesper Larsen, Isabella Skandorff, Monika Gad, Kim Holmstrøm
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
3D cancer cell cultures have enabled new opportunities for replacing compound testing in experimental animals. However, most solid tumors are composed of multiple cell types, including fibroblasts. In this study we developed multicellular tumor heter
Externí odkaz:
https://doaj.org/article/ed34f1c7b90146b7bb62572bf29dc2c3
Autor:
Jaslin Pallikkunnath James, Boye Schnack Nielsen, Ib Jarle Christensen, Ebbe Langholz, Mikkel Malham, Tim Svenstrup Poulsen, Kim Holmstrøm, Lene Buhl Riis, Estrid Høgdall
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Differential diagnosis of inflammatory bowel disease (IBD) to Crohn’s disease (CD) or ulcerative colitis (UC) is crucial for treatment decision making. With the aim of generating a clinically applicable molecular-based tool to classify IBD
Externí odkaz:
https://doaj.org/article/d978c2381668411fa9631bc9104e9339
Autor:
Christopher J. Barnes, Maria Asplund, Maja-Lisa Clausen, Linett Rasmussen, Caroline Meyer Olesen, Yasemin Topal Yüksel, Paal Skytt Andersen, Thomas Litman, Kim Holmstrøm, Lene Bay, Blaine Gabriel Fritz, Thomas Bjarnsholt, Tove Agner, Anders Johannes Hansen
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract There has been considerable research into the understanding of the healthy skin microbiome. Similarly, there is also a considerable body of research into whether specific microbes contribute to skin disorders, with atopic dermatitis (AD) rou
Externí odkaz:
https://doaj.org/article/0a8ec7e8ca4f4a558e5a445308b7fd0c
Autor:
Troels Ronco, Line H. Kappel, Maria F. Aragao, Niccolo Biagi, Søren Svenningsen, Jørn B. Christensen, Anders Permin, Lasse Saaby, Kim Holmstrøm, Janne K. Klitgaard, Artur J. Sabat, Viktoria Akkerboom, Monica Monaco, Marco Tinelli, Alexander W. Friedrich, Bimal Jana, Rikke H. Olsen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Multidrug-resistant pathogens constitute a serious global issue and, therefore, novel antimicrobials with new modes of action are urgently needed. Here, we investigated the effect of a phenothiazine derivative (JBC 1847) with high antimicrobial activ
Externí odkaz:
https://doaj.org/article/a70ca383e2d94fc0aec69fc9b38b1f43
Autor:
Silvia Aldi, Ljubica Perisic Matic, Gregory Hamm, Daniëlle van Keulen, Dennie Tempel, Kim Holmstrøm, Agnieszka Szwajda, Boye Schnack Nielsen, Valur Emilsson, Rima Ait-Belkacem, Mariette Lengquist, Gabrielle Paulsson-Berne, Per Eriksson, Jan H.N. Lindeman, Alain J. Gool, Jonathan Stauber, Ulf Hedin, Eva Hurt-Camejo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 17-28 (2018)
Variants in the PLPP3 gene encoding for lipid phosphate phosphohydrolase 3 have been associated with susceptibility to atherosclerosis independently of classical risk factors. PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflammatory, pro-thr
Externí odkaz:
https://doaj.org/article/7bfc8ac6211a4952996ab2d554be695f
Autor:
Danielle van Keulen, Marianne G Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H N Lindeman, Alain J van Gool, Maarten D Sollewijn Gelpke, Hans M G Princen, Dennie Tempel
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221477 (2019)
ObjectivePrevious studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and
Externí odkaz:
https://doaj.org/article/ca346d3188e04a0dac053e012ce18eb6
Autor:
Boye Schnack, Nielsen, Jesper, Larsen, Jakob, Høffding, Son Ly, Nhat, Natasha Helleberg, Madsen, Trine, Møller, Bjørn, Holst, Kim, Holmstrøm
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2348
Cancer cell spheroids are considered important preclinical tools to evaluate the efficacy of new drugs. In cancer cell spheroids, the cells assemble and grow in 3D structures with cell contact interactions that are partly impermeable, which leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4d007d11ea8f789a2496938717f0647
https://pubmed.ncbi.nlm.nih.gov/34160803
https://pubmed.ncbi.nlm.nih.gov/34160803
Autor:
Trine Møller, Kim Holmstrøm, Bjørn Holst, Jesper Larsen, Natasha Helleberg Madsen, Son Ly Nhat, Boye Schnack Nielsen, Jakob Høffding
Publikováno v:
Long Non-Coding RNAs in Cancer ISBN: 9781071615805
Cancer cell spheroids are considered important preclinical tools to evaluate the efficacy of new drugs. In cancer cell spheroids, the cells assemble and grow in 3D structures with cell contact interactions that are partly impermeable, which leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d75e6d6c413c8d09ac7b0a66fb2bfac1
https://doi.org/10.1007/978-1-0716-1581-2_8
https://doi.org/10.1007/978-1-0716-1581-2_8
Autor:
Boye Schnack Nielsen, M. Pilar J. Stella, Björn-Ole Meyer, Kim Holmstrøm, Dominik Marti, Bjørn Holst, Peter Andersen
Publikováno v:
Multiphoton Microscopy in the Biomedical Sciences XX.
Endoscopes and other optical, non-invasive diagnostic instruments require measurable parameters (biomarkers) that reliably represent early signs of cancer. These biomarkers are challenging to identify in complex tissues due to their dependence on env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b44ece9c4a752a9b6cb3a6889aa9d1d0
https://doi.org/10.1117/12.2546141
https://doi.org/10.1117/12.2546141
Publikováno v:
Scandinavian Journal of Immunology. 85:113-121
Regulatory CD4+ T cells (Tregs) are pivotal for prevention of autoimmunity. The use of Tregs is therefore of increasing interest in in vitro drug screening assays as well as for a cytotherapy per se against autoimmune disorders. For both purposes, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1704d0fa676e0239b4f20da54e2eb555
https://doi.org/10.1111/sji.12517
https://doi.org/10.1111/sji.12517