Quantifying Cell Death Induced by the NLRC4 Inflammasome.

Autor: Emming S; Institute for Molecular Bioscience, and Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Australia., Monteleone MM; Institute for Molecular Bioscience, and Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Australia., Kambara H; Quench Bio, Inc., Cambridge, MA, USA., Starchenko A; Quench Bio, Inc., Cambridge, MA, USA., Alley J; Quench Bio, Inc., Cambridge, MA, USA., Nolan MA; Quench Bio, Inc., Cambridge, MA, USA., Li W; Quench Bio, Inc., Cambridge, MA, USA., Kilty I; Quench Bio, Inc., Cambridge, MA, USA., Schroder K; Institute for Molecular Bioscience, and Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Australia. k.schroder@imb.uq.edu.au.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2696, pp. 199-210.

Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium

Autor: Porter, JD, Watson, J, Roberts, LR, Gill, SK, Groves, H, Dhariwal, J, Almond, MH, Wong, E, Walton, RP, Jones, LH, Tregoning, J, Kilty, I, Johnston, SL, Edwards, MR

Publikováno v: Journal of Antimicrobial Chemotherapy

BACKGROUND: Exacerbations of asthma and COPD are triggered by rhinoviruses. Uncontrolled inflammatory pathways, pathogenic bacterial burden and impaired antiviral immunity are thought to be important factors in disease severity and duration. Macrolid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6c9e51658de696ce8d266aee96e4a33f
http://europepmc.org/articles/PMC5031920

Corrigendum to "Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling" [International Journal of Cardiology 167 (2013) 2630-2637].

Autor: Kojonazarov B; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Sydykov A; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Pullamsetti SS; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany; Department of Lung Development and Remodelling, Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Luitel H; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Dahal BK; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Kosanovic D; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Tian X; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Majewski M; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Baumann C; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Evans S; Pfizer Global Research and Development, Sandwich, United Kingdom., Phillips P; Pfizer Global Research and Development, Sandwich, United Kingdom., Fairman D; Pfizer Global Research and Development, Sandwich, United Kingdom., Davie N; Pfizer Global Research and Development, Sandwich, United Kingdom., Wayman C; Pfizer Global Research and Development, Sandwich, United Kingdom., Kilty I; Pfizer Global Research and Development, Sandwich, United Kingdom., Weissmann N; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Grimminger F; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Seeger W; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany; Department of Lung Development and Remodelling, Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Ghofrani HA; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany., Schermuly RT; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research, Germany. Electronic address: ralph.schermuly@innere.med.uni-giessen.de.

Publikováno v: International journal of cardiology [Int J Cardiol] 2022 Jun 15; Vol. 357, pp. 152-153. Date of Electronic Publication: 2022 Mar 30.

Transcriptomic analysis reveals distinct effects of cigarette smoke on murine airspace and bone-marrow derived macrophages.

Autor: Faherty, Lynne^1,2 (AUTHOR), Zhang, William Z.³ (AUTHOR), Salih, Mays M.⁴ (AUTHOR), Robinson, Elektra K.⁴ (AUTHOR), Perez, Elizabeth³ (AUTHOR), Kim, Kihwan³ (AUTHOR), Carpenter, Susan⁴ (AUTHOR), Cloonan, Suzanne M.^1,2,3 (AUTHOR) suzanne.cloonan@tcd.ie

Publikováno v: Respiratory Research. 8/24/2024, Vol. 25 Issue 1, p1-8. 8p.

Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages.

Autor: Belchamber KBR; Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK., Singh R; Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK., Batista CM; Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK., Whyte MK; MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Dockrell DH; MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Kilty I; Inflammation and Immunology Research Unit, Pfizer Inc, Cambridge, MA, USA., Robinson MJ; MedImmune, Cambridge, UK., Wedzicha JA; Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK., Barnes PJ; Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK., Donnelly LE; Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK l.donnelly@imperial.ac.uk.

Publikováno v: The European respiratory journal [Eur Respir J] 2019 Oct 10; Vol. 54 (4). Date of Electronic Publication: 2019 Oct 10 (Print Publication: 2019).