Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Killer Cells, Natural / immunology"'
1
NBAS variants are associated with quantitative and qualitative NK and B cell deficiency
Autor: Seham Alameer, Tobias Schwerd, Giuseppe Indolfi, Joseph A. Church, Adelheid Cerwenka, Dominic Lenz, Ivo Barić, Jidnyasa Gujar, Thomas Giese, Johann Greil, Christian Staufner, Jens Pahl, Felix Distelmaier, Georg F. Hoffmann, Eberhard Lurz, Nikolas Boy, Anke Dick, Bianca Peters, Ellen Crushell, Holger Prokisch, Christoph Klein, Meena Balasubramanian, Stefan Kölker, Fabian Hauck, Daniele Serranti
Publikováno v: J. Clin. Immunol., DOI: 10.1007/s10875-021-01110-7 (2021)
Journal of Clinical Immunology
Purpose Biallelic pathogenic NBAS variants manifest as a multisystem disorder with heterogeneous clinical phenotypes such as recurrent acute liver failure, growth retardation, and susceptibility to infections. This study explores how NBAS-associated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7176568d4fc4003562f22a1716e15672
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62807
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2
Expression of NK cell receptor ligands in primary colorectal cancer tissue in relation to the phenotype of circulating NK- and NKT cells, and clinical outcome
Autor: Daniëlle Krijgsman, Wouter Hendrickx, Marianne Hokland, Rob A. E. M. Tollenaar, Davide Bedognetti, Jessica Roelands, Cornelia H.L.A. Wieringa, Morten Andersen, Peter J. K. Kuppen
Publikováno v: Krijgsman, D, Roelands, J, Andersen, M N, Wieringa, C H L A, Tollenaar, R A E M, Hendrickx, W, Bedognetti, D, Hokland, M & Kuppen, P J K 2020, ' Expression of NK cell receptor ligands in primary colorectal cancer tissue in relation to the phenotype of circulating NK-and NKT cells, and clinical outcome ', Molecular Immunology, vol. 128, pp. 205-218 . https://doi.org/10.1016/j.molimm.2020.10.012
Molecular Immunology, 128, 205-218. PERGAMON-ELSEVIER SCIENCE LTD
Introduction Natural killer (NK) cells and natural killer T (NKT) cells are implicated in the development and progression of colorectal cancer (CRC). Tumor cells express NK cell receptor ligands that modulate their function. This study aimed to inves
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3c413092e22a00923150a44af7ee8b
https://pure.au.dk/portal/da/publications/expression-of-nk-cell-receptor-ligands-in-primary-colorectal-cancer-tissue-in-relation-to-the-phenotype-of-circulating-nk-and-nkt-cells-and-clinical-outcome(c20f24b1-44c6-49c9-a6d0-60172e5cca65).html
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3
Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient
Autor: Lars Fugger, Ralf Gold, Kate Attfield, Astrid K. N. Iversen, Hannah Wurm, Aiden Haghikia
Publikováno v: Attfield, K, Iversen, A K, Gold, R, Fugger, L & Haghikia, A 2020, ' Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient ', Multiple sclerosis (Houndmills, Basingstoke, England), vol. 26, no. 10, pp. 1261-1264 . https://doi.org/10.1177/1352458520943791
Multiple Sclerosis (Houndmills, Basingstoke, England)
Approximately 200,000 multiple sclerosis (MS) patients worldwide receive B-cell-depleting immunotherapy with rituximab (anti-CD20), which eliminates the ability to generate an antibody response to new infections. As severe acute respiratory syndrome
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d12eb597e93dc5973e5a82e0a59c11
https://ora.ox.ac.uk/objects/uuid:1394a7bc-38fc-4e9a-b856-10f5a22a4f2a
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5
Chemokines cooperate with TNF to provide protective anti-viral immunity and to enhance inflammation
Autor: Alejo, A., Ruiz-Argüello, M. B., Pontejo, S. M., Fernández De Marco, M. D. M., Saraiva, M., Hernáez, B., Alcamí, A.
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
The role of cytokines and chemokines in anti-viral defense has been demonstrated, but their relative contribution to protective anti-viral responses in vivo is not fully understood. Cytokine response modifier D (CrmD) is a secreted receptor for TNF a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::41c4c896a7805080dbc72b7e9051afc6
http://link.springer.com/article/10.1038/s41467-018-04098-8
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6
Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry
Autor: Amélie Rousselière, Laurence Delbos, Céline Bressollette, Maïlys Berthaume, Béatrice Charreau
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 263, p 263 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 263
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 23 (1), pp.263. ⟨10.3390/ijms23010263⟩
HCMV drives complex and multiple cellular immune responses, which causes a persistent immune imprint in hosts. This study aimed to achieve both a quantitative determination of the frequency for various anti-HCMV immune cell subsets, including CD8 T,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c251519185848aca94e1699be5c0f0b
https://doi.org/10.3390/ijms23010263
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7
Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab
Autor: Torben Plesner, René J. P. Musters, Berris van Kessel, Jeroen F. van Velzen, A. Kate Sasser, Pino J. Poddighe, Marloes E.C. Broekmans, Tuna Mutis, Inger S. Nijhof, Henk M. Lokhorst, Jakub Krejcik, Richard W.J. Groen, Kris A. Frerichs, Sonja Zweegman, Niels W.C.J. van de Donk, Andries C. Bloem, Johan van Meerloo, Christopher Chiu
Publikováno v: Krejcik, J, Frerichs, K A, Nijhof, I S, van Kessel, B, van Velzen, J, Bloem, A C, Broekmans, M, Zweegman, S, van Meerloo, J, Musters, R J, Poddighe, P, Groen, R, Chiu, C, Plesner, T, Lokhorst, H M, Sasser, A K, Mutis, T & van de Donk, N W C J 2017, ' Monocytes and granulocytes reduce CD38 expression levels on myeloma cells in patients treated with daratumumab ', Clinical Cancer Research, vol. 23, no. 24, pp. 7498-7511 . https://doi.org/10.1158/1078-0432.CCR-17-2027
Krejcik, J, Frerichs, K A, Nijhof, I S, van Kessel, B, van Velzen, J F, Bloem, A C, Broekmans, M E C, Zweegman, S, van Meerloo, J, Musters, R J P, Poddighe, P J, Groen, R W J, Chiu, C, Plesner, T, Lokhorst, H M, Sasser, A K, Mutis, T & van de Donk, N W C J 2017, ' Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab ', Clinical Cancer Research, vol. 23, no. 24, pp. 7498-7511 . https://doi.org/10.1158/1078-0432.CCR-17-2027
Clinical Cancer Research, 23(24), 7498-7511. American Association for Cancer Research Inc.
Purpose: Daratumumab treatment results in a marked reduction of CD38 expression on multiple myeloma cells. The aim of this study was to investigate the clinical implications and the underlying mechanisms of daratumumab-mediated CD38 reduction. Experi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a411b4972ab21d4db661d3cca064dd68
https://doi.org/10.1158/1078-0432.ccr-17-2027
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8
NKp46 is a diagnostic biomarker and may be a therapeutic target in gastrointestinal T-cell lymphoproliferative diseases: A CELAC study
Autor: Nicolas Guegan, Florence Lhospice, Sascha Cording, Amélie Trinquand, Julie Bruneau, Olivier Hermine, Virginie Verkarre, Nicole Brousse, Christophe Cellier, Georgia Malamut, Elizabeth Macintyre, Felipe Suarez, Laurent Frenzel, Vahid Asnafi, Morgane Cheminant, Sherine Khater, Bertrand Meresse, Ambroise Marçais, Nadine Cerf-Bensussan, Tom van Gils, Chris J. J. Mulder, Thierry Jo Molina, Ludovic Lhermitte, C. cile Bonnafous, David Sibon, Anne-Sophie Jannot, Richard Delarue, Laurent Pouyet
Publikováno v: Gut, 68(8), 1396-1405. BMJ Publishing Group
Gut
Gut, BMJ Publishing Group, 2019, 68 (8), pp.1396-1405. ⟨10.1136/gutjnl-2018-317371⟩
Cheminant, M, Bruneau, J, Malamut, G, Sibon, D, Guegan, N, van Gils, T, Cording, S, Trinquand, A, Verkarre, V, Lhermitte, L, Brousse, N, Jannot, A-S, Khater, S, Frenzel, L, Delarue, R, Suarez, F, Marçais, A, Mulder, C J J, Macintyre, E, Asnafi, V, Pouyet, L, Bonnafous, C C, Lhospice, F, Molina, T J, Meresse, B, Cellier, C, Cerf-Bensussan, N & Hermine, O 2019, ' NKp46 is a diagnostic biomarker and may be a therapeutic target in gastrointestinal T-cell lymphoproliferative diseases: A CELAC study ', Gut, vol. 68, no. 8, pp. 1396-1405 . https://doi.org/10.1136/gutjnl-2018-317371
Gut, 2019, 68 (8), pp.1396-1405. ⟨10.1136/gutjnl-2018-317371⟩
ObjectivesPrimary GI T-cell lymphoproliferative diseases (T-LPD) are heterogeneous entities, which raise difficult diagnosis and therapeutic challenges. We have recently provided evidences that lymphomas complicating coeliac disease (CD) arise from i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bf16bc8e37754465b0cd121bf54c22
https://research.vumc.nl/en/publications/c070e3fd-4cc5-486e-8710-e1f8ba369480
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9
Features of Human Decidual NK Cells in Healthy Pregnancy and During Viral Infection
Autor: Jabrane-Ferrat, Nabila
Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2019, 10, pp.1397. ⟨10.3389/fimmu.2019.01397⟩
Frontiers in Immunology, 2019, 10, pp.1397. ⟨10.3389/fimmu.2019.01397⟩
International audience; The hallmark of human early pregnancy is the accumulation of a unique population of Natural Killer (dNK) cells at the main maternal-fetal interface, the decidua basalis. dNK cells play a crucial role in successful placentation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5c979fb9d97bbbb520b0d992c71839c1
https://hal.archives-ouvertes.fr/hal-02405520
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10
Outcomes of controlled human malaria infection after BCG vaccination
Autor: Christine Stabell Benn, Farid Keramati, Robert W. Sauerwein, Marga van de Vegte-Bolmer, Quirijn de Mast, Rianne Stoter, Marije C. Behet, Geert-Jan van Gemert, Rob J.W. Arts, Wouter Graumans, Peter Aaby, Reinout van Crevel, Karina Teelen, Simone J.C.F.M. Moorlag, Annie S. P. Yang, Jona Walk, Cornelus C. Hermsen, L. Charlotte J. de Bree, André J. A. M. van der Ven, Mihai G. Netea
Publikováno v: Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Walk, J, de Bree, L C J, Graumans, W, Stoter, R, van Gemert, G J, van de Vegte-Bolmer, M, Teelen, K, Hermsen, C C, Arts, R J W, Behet, M C, Keramati, F, Moorlag, S J C F M, Yang, A S P, van Crevel, R, Aaby, P, de Mast, Q, van der Ven, A J A M, Stabell Benn, C, Netea, M G & Sauerwein, R W 2019, ' Outcomes of controlled human malaria infection after BCG vaccination ', Nature Communications, vol. 10, 874 . https://doi.org/10.1038/s41467-019-08659-3
Nature Communications
Recent evidence suggests that certain vaccines, including Bacillus-Calmette Guérin (BCG), can induce changes in the innate immune system with non-specific memory characteristics, termed ‘trained immunity’. Here we present the results of a random
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df028d745c66717cd0089fe85eabd210
https://hdl.handle.net/2066/202100
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