Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kiley A. Lawrence"'
Autor:
Jessica E. Thaxton, Dongjun Chung, Lauren E. Ball, Rob A. Robino, Kiley A. Lawrence, Katie E. Hurst
The requisites for protein translation in T cells are poorly understood and how translation shapes the antitumor efficacy of T cells is unknown. Here we demonstrated that IL15-conditioned T cells were primed by the metabolic energy sensor AMP-activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6799f03d48edb6073db519bb094e2e00
https://doi.org/10.1158/2326-6066.c.6550122.v1
https://doi.org/10.1158/2326-6066.c.6550122.v1
Autor:
Jessica E. Thaxton, Lee R. Leddy, Zeke J. Walton, Matthew T. Essman, Kiley A. Lawrence, Katie E. Hurst
Quantification and viability of T cell groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160f6954ca6b9a5b70d12594183ff3ce
https://doi.org/10.1158/2326-6066.22540186.v1
https://doi.org/10.1158/2326-6066.22540186.v1
Autor:
Jessica E. Thaxton, Lee R. Leddy, Zeke J. Walton, Matthew T. Essman, Kiley A. Lawrence, Katie E. Hurst
mtROS+ CD8 TILs are highly activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d290c80d754f25c557f4efe1b1fd56ae
https://doi.org/10.1158/2326-6066.22540183.v1
https://doi.org/10.1158/2326-6066.22540183.v1
Autor:
Jessica E. Thaxton, Lee R. Leddy, Zeke J. Walton, Matthew T. Essman, Kiley A. Lawrence, Katie E. Hurst
Tumor antigen–specific T cells rapidly lose energy and effector function in tumors. The cellular mechanisms by which energy loss and inhibition of effector function occur in tumor-infiltrating lymphocytes (TILs) are ill-defined, and methods to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::319a4b2f18d33b0588fd34b0dc9592ef
https://doi.org/10.1158/2326-6066.c.6549307.v1
https://doi.org/10.1158/2326-6066.c.6549307.v1
Autor:
Jessica E. Thaxton, Lee R. Leddy, Zeke J. Walton, Matthew T. Essman, Kiley A. Lawrence, Katie E. Hurst
Protein Expression, Shotgun Proteomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e02fd8b917393791a5d3f3d3bcd6581
https://doi.org/10.1158/2326-6066.22540177
https://doi.org/10.1158/2326-6066.22540177
Autor:
Dongjun Chung, Rob A Robino, Jessica E. Thaxton, Kiley A. Lawrence, Katie E. Hurst, Lauren E. Ball
Publikováno v:
Cancer Immunology Research. 8:587-595
The requisites for protein translation in T cells are poorly understood and how translation shapes the antitumor efficacy of T cells is unknown. Here we demonstrated that IL15-conditioned T cells were primed by the metabolic energy sensor AMP-activat
Autor:
Lety Reyes Angeles, Danyelle M. Townsend, Nathan G. Dolloff, Katie E. Hurst, Kiley A. Lawrence, Zhi-Wei Ye, Jie Zhang, Jessica E. Thaxton
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
Effective cancer therapies simultaneously restrict tumor cell growth and improve anti-tumor immune responses. Targeting redox-dependent protein folding enzymes within the endoplasmic reticulum (ER) is an alternative approach to activation of the unfo