Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kiley A. Lawrence"'
Autor:
Jessica E. Thaxton, Dongjun Chung, Lauren E. Ball, Rob A. Robino, Kiley A. Lawrence, Katie E. Hurst
The requisites for protein translation in T cells are poorly understood and how translation shapes the antitumor efficacy of T cells is unknown. Here we demonstrated that IL15-conditioned T cells were primed by the metabolic energy sensor AMP-activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6799f03d48edb6073db519bb094e2e00
https://doi.org/10.1158/2326-6066.c.6550122.v1
https://doi.org/10.1158/2326-6066.c.6550122.v1
Autor:
Jessica E. Thaxton, Lee R. Leddy, Zeke J. Walton, Matthew T. Essman, Kiley A. Lawrence, Katie E. Hurst
Quantification and viability of T cell groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160f6954ca6b9a5b70d12594183ff3ce
https://doi.org/10.1158/2326-6066.22540186.v1
https://doi.org/10.1158/2326-6066.22540186.v1
Autor:
Jessica E. Thaxton, Lee R. Leddy, Zeke J. Walton, Matthew T. Essman, Kiley A. Lawrence, Katie E. Hurst
Tumor antigen–specific T cells rapidly lose energy and effector function in tumors. The cellular mechanisms by which energy loss and inhibition of effector function occur in tumor-infiltrating lymphocytes (TILs) are ill-defined, and methods to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::319a4b2f18d33b0588fd34b0dc9592ef
https://doi.org/10.1158/2326-6066.c.6549307.v1
https://doi.org/10.1158/2326-6066.c.6549307.v1
Autor:
Dongjun Chung, Rob A Robino, Jessica E. Thaxton, Kiley A. Lawrence, Katie E. Hurst, Lauren E. Ball
Publikováno v:
Cancer Immunology Research. 8:587-595
The requisites for protein translation in T cells are poorly understood and how translation shapes the antitumor efficacy of T cells is unknown. Here we demonstrated that IL15-conditioned T cells were primed by the metabolic energy sensor AMP-activat
Autor:
Lety Reyes Angeles, Danyelle M. Townsend, Nathan G. Dolloff, Katie E. Hurst, Kiley A. Lawrence, Zhi-Wei Ye, Jie Zhang, Jessica E. Thaxton
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
Effective cancer therapies simultaneously restrict tumor cell growth and improve anti-tumor immune responses. Targeting redox-dependent protein folding enzymes within the endoplasmic reticulum (ER) is an alternative approach to activation of the unfo
Autor:
Jessica E. Thaxton, Katie E. Hurst, Zeke J. Walton, Matthew T. Essman, Lee R. Leddy, Kiley A. Lawrence
Tumor antigen–specific T cells rapidly lose energy and effector function in tumors. The cellular mechanisms by which energy loss and inhibition of effector function occur in tumor-infiltrating lymphocytes (TILs) are ill-defined, and methods to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6283ad5ed73da437a2d72d88ab13bb
https://europepmc.org/articles/PMC6397687/
https://europepmc.org/articles/PMC6397687/
Autor:
Matthew T. Essman, William R. Barfield, Jessica E. Thaxton, Katie E. Hurst, Thomas W. Valente, Lee R. Leddy, Kiley A. Lawrence, Zeke J. Walton, Molly G. Sekar
Publikováno v:
Journal of Musculoskeletal Research. 23:2050017
Background: Osteoarthritis (OA) is a leading cause of morbidity affecting 54 million Americans per year at an annual cost of 304 billion dollars to the US healthcare system. OA is characterized as a disease of joint wear and tear, but mounting eviden