Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Kile McFadden"'
1
Murine social stress results in long lasting voiding dysfunction
Autor: Sandra Luz, Christopher J. Long, Douglas A. Canning, Steven H. Seeholzer, Kile McFadden, Stephen A. Zderic, Stephan Butler, Joanna Fesi, Rita J. Valentino, Lynn A. Spruce
Publikováno v: Physiology & Behavior. 183:10-17
Repeated exposure to social stress shifts the voiding phenotype in male mice leading to bladder wall remodeling and is associated with increased expression of the stress neuropeptide, corticotropin-releasing factor (CRF) in Barrington's nucleus neuro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ab3a96b1c90460543a52aba79ab42f
https://doi.org/10.1016/j.physbeh.2017.09.020
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2
Abstract 4918: Artificial intelligence-assisted macrophage identification in tumor biopsies
Autor: Kelsey Weigel, Will Paces, Elliott Ergon, Jeni Caldara, Kile McFadden, Cris Luengo, Roberto Gianani, Bharathi Vennapusa
Publikováno v: Cancer Research. 79:4918-4918
Understanding response to immunotherapy requires accurate and complete characterization of tumor-associated immune cells in order to fully contextualize the immuno-oncology biomarker expression. Current standard practices surrounding enumeration of b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6191b2dd8319456946d7641825e70dc3
https://doi.org/10.1158/1538-7445.am2019-4918
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3
Abstract 1694: Computational analysis of multiplexed immunohistochemistry for understanding immune profiles in clinical biopsies
Autor: Mandy Bell, Kile McFadden, Brooke Hirsch, Ben Landis, G. David Young, Karen A. Ryall, Nick Landis, Joseph S. Krueger
Publikováno v: Cancer Research. 78:1694-1694
Using immunohistochemistry (IHC) to examine immune infiltrates in tissue biopsies to support exploratory investigations for immuno-oncology drug development is critical for understanding the abundance and spatial relationships of different immune cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4020f03d2ac28523856d6b56ef8b4e08
https://doi.org/10.1158/1538-7445.am2018-1694
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4
A corticotropin-releasing factor receptor antagonist improves urodynamic dysfunction produced by social stress or partial bladder outlet obstruction in male rats
Autor: Kile McFadden, Rita J. Valentino, Stephen A. Zderic, Susan K. Wood, John H. Wolfe, Tagan A. Griffin
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 304:R940-R950
Barrington's nucleus, in the pons, regulates micturition through spinal projections to preganglionic parasympathetic neurons. The stress neuropeptide CRF is prominent in these projections and has an inhibitory influence. Social stress in rats causes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076055291207680f5fba808403d16407
https://doi.org/10.1152/ajpregu.00257.2012
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5
Overexpression of corticotropin-releasing factor in Barrington’s nucleus neurons by adeno-associated viral transduction: effects on bladder function and behavior
Autor: Kile McFadden, John H. Wolfe, Valerie Levy, Tagan A. Griffin, Rita J. Valentino
Publikováno v: European Journal of Neuroscience. 36:3356-3364
The stress-related neuropeptide, corticotropin-releasing factor (CRF), is prominent in neurons of the pontine micturition center, Barrington's nucleus. These neurons co-innervate spinal preganglionic neurons that control the bladder, and locus coerul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad22c44a7c3fafc0b6b771698c7f880a
https://doi.org/10.1111/j.1460-9568.2012.08250.x
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6
Corticotropin-Releasing Factor in the Norepinephrine Nucleus, Locus Coeruleus, Facilitates Behavioral Flexibility
Autor: Kile McFadden, Rebecca Han, Rita J. Valentino, Wei-Wen Wang, Kevin Snyder
Publikováno v: Neuropsychopharmacology. 37:520-530
Corticotropin-releasing factor (CRF), the stress-related neuropeptide, acts as a neurotransmitter in the brain norepinephrine nucleus, locus coeruleus (LC), to activate this system during stress. CRF shifts the mode of LC discharge from a phasic to a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66947cd7b160428b5cc3db79d503d4e
https://doi.org/10.1038/npp.2011.218
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8
Depressive and cardiovascular disease comorbidity in a rat model of social stress: a putative role for corticotropin-releasing factor
Autor: Kile McFadden, Dimitri E. Grigoriadis, Susan K. Wood, Rita J. Valentino, Seema Bhatnagar
Publikováno v: Psychopharmacology. 222(2)
Depression is associated with medical comorbidities, particularly cardiovascular disease. However, mechanisms linking depression and cardiovascular disease remain unclear.This study investigated whether the rat resident-intruder model of social stres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b6a1a89c5caa99bd1f68bed4316ba1
https://pubmed.ncbi.nlm.nih.gov/22322324
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9
Early adolescence as a critical window during which social stress distinctly alters behavior and brain norepinephrine activity
Autor: Seema Bhatnagar, Rita J. Valentino, Brian Bingham, Sheryl G. Beck, Xiao-Yan Zhang, Kile McFadden
Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 36(4)
Many neural programs that shape behavior become established during adolescence. Adverse events at this age can have enduring consequences for both adolescent and adult mental health. Here we show that repeated social stress at different stages of ado
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc29dc9d8763554c5ef4b06d9a2c213
https://pubmed.ncbi.nlm.nih.gov/21178981
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