The prohibitin complex regulates macrophage fatty acid composition, plasma membrane packing, and lipid raft-mediated inflammatory signaling.

Autor: Matthews CEP; Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States., Fussner LA; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States., Yaeger M; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States., Aloor JJ; Diabetes and Obesity Institute, Department of Physiology, East Carolina University, Greenville, NC, United States., Reece SW; Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States., Kilburg-Basnyat BJ; Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States., Varikuti S; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States., Luo B; Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States., Inks M; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States., Sergin S; Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States., Schmidt CA; Diabetes and Obesity Institute, Department of Physiology, East Carolina University, Greenville, NC, United States., Neufer PD; Diabetes and Obesity Institute, Department of Physiology, East Carolina University, Greenville, NC, United States., Pennington ER; Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill, NC, United States., Fisher-Wellman KH; Diabetes and Obesity Institute, Department of Physiology, East Carolina University, Greenville, NC, United States., Chowdhury SM; Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX, United States., Fessler MB; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, United States., Fenton JI; Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States., Anderson EJ; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, FOE Diabetes Research Center, University of Iowa, Iowa City, IA, United States., Shaikh SR; Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill, NC, United States., Gowdy KM; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States. Electronic address: kymberly.gowdy@osumc.edu.

Publikováno v: Prostaglandins, leukotrienes, and essential fatty acids [Prostaglandins Leukot Essent Fatty Acids] 2023 Mar; Vol. 190, pp. 102540. Date of Electronic Publication: 2023 Jan 19.

Pgam5-mediated PHB2 dephosphorylation contributes to endotoxemia-induced myocardial dysfunction by inhibiting mitophagy and the mitochondrial unfolded protein response.

Autor: Chen Cai, Ziying Li, Zemao Zheng, Zhongzhou Guo, Qian Li, Shuxian Deng, Nengxian Shi, Qing Ou, Hao Zhou, Zhigang Guo, Zhongqing Chen, Hang Zhu

Publikováno v: International Journal of Biological Sciences; 2023, Vol. 19 Issue 14, p4657-4671, 15p