Peptidyl aldehyde derivatives as potent and selective inhibitors of cathepsin L

Autor: Kohji Yamaguchi, Sanae Sigeizumi, Tomoko Tsuji, Kiyosi Kondo, Takeo Kobori, Je-Tae Woo, Kikuo Sugimoto

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 5:1501-1504

A series of peptidyl aldehyde derivatives were synthesized and tested for their inhibitory effects on several cysteine proteases and a serine protease. These componds showed no inhibition for α-chymotrypsin at the concentration less than 1000 ng/ml,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ee3f1d2dfa6fe4939e19dc6ade3dbb1
https://doi.org/10.1016/0960-894x(95)00236-m

Chemical modification of poly(substituted-acetylene). VI. Introduction of fluoroalkyl group into poly(1-trimethylsilyl-1-propyne) and the improved ethanol permselectivity at pervaporation

Autor: Kiyohide Matsui, Yuriko Takamura, Kikuo Sugimoto, Yu Nagase

Publikováno v: Journal of Applied Polymer Science. 43:1227-1232

In order to improve the separation characteristics of membranes for pervaporation, the introduction of fluoroalkyl groups into poly(1-trimethylsilyl-1-propyne) (PTMSP) was achieved by two methods. First, 3,3,3-trifluoropropyldimethylsilylated PTMSP w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5df7f006578902b12ecf85c29d9b97db
https://doi.org/10.1002/app.1991.070430703

[A comparative study between cefpirome (CPR) and ceftazidime (CAZ) in respiratory tract infections]

Autor: Rinzo SOEJIMA, Masaru SUMI, Jiro HINO, Niro OKIMOTO, Yoshikazu KAWAKAMI, Etsuro YAMAGUCHI, Tsugio TERAI, Takashi YOSHIKAWA, Kazuo TAKAOKA, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Hidetoshi SHIBAKI, Koji TANEICHI, Tsuyoshi KIKUIRI, Masahide SHINOHARA, Akira MIWA, Choei ITO, Mitsuo SATO, Akira SUZUKI, Yasuhito HONDA, Kyuichiro SEKINE, Yomei HIRAGA, Mitsuhide OMICHI, Shinya YASUDA, Tetsuji KOROKU, Susumu ITO, Shoji KASAGI, Sokichi ONODERA, Yoshinobu OSAKI, Hiroyuki MATSUMOTO, Takafumi OTA, Eiichi SAKAI, Tetsuo SHIMIZU, Nobuhiro SASAKI, Toshiaki FUJIKANE, Satoshi FUJIUCHI, Toshiaki SHISHIDO, Kazuo TAKEBE, Atsuko YANADA, Mitsuo MASUDA, Seiichi MURAKAMI, Kenichi IMAMURA, Toyokazu TAMURA, Katsumi ENDO, Hideya MURABAYASHI, Shigeru OCHIAI, Hidekazu SAWADA, Michitaka SHIMURA, Masashi TAMURA, Kazuki KONISHI, Taiji YOSHIDA, Morio SUDO, Takeshi BANDO, Nobuhisa SATO, Masayuki OURA, Tetsuro UNOURA, Takashi MOURI, Tamotsu TAKISHIMA, Yasuo TANNO, Kunio KUDO, Munehiko ISHII, Masaharu SUGIYAMA, Masakichi MOTOMIYA, Akira WATANABE, Kosaku NAGAI, Kazuo SATO, Kiyoshi KONNO, Teruo HASUIKE, Kuniharu SHIDA, Satoshi SHINDO, Izumi HAYASHI, Jingoro SHIMADA, Masaki YOSHIDA, Atsushi SAITO, Koya SHIBA, Masanobu KAJI, Seiji HORI, Osamu SAKAI, Hideo MIYASHITA, Yasuo ONO, Masumi BABA, Hiroyuki KOBAYASHI, Hiroshi OSHITANI, Hiroshi MIURA, Takashi INOUE, Kaoru SHIMADA, Mieko GOTO, Hajime GOTO, Yasuyuki SANO, Yasufumi MIYAMOTO, Yasuo ARAI, Kanzaburo MATSUMURA, Yoshitaka NAKAMORI, Koji NARUI, Masayuki NOGUCHI, Tatsuo NAKATANI, Koichiro NAKATA, Iwao SAKURAI, Takeo IMAI, Fumio MATSUMOTO, Shigeki ODAGIRI, Masanori MATSUMURA, Kaneo SUZUKI, Kou MUROHASHI, Hiroshi TAKAHASHI, Kenichi TAKAHASHI, Teruaki YOSHIOKA, Izumi KOYAMA, Takashi OGURA, Masaaki ARAKAWA, Koichi WADA, Takashi KAWASHIMA, Masanaga TAKATO, Hidenori KUMANO, Nobuki AOKI, Tatsuo SATAKE, Kenichi YAMAKI, Ryujiro SUZUKI, Kenzo TAKAGI, Hitoshi TANAKA, Masatoshi IMAI, Toshiaki TSUNODA, Yoshiaki WATANABE, Toshihiko TAKEUCHI, Yoshimitsu HAYASHI, Kazuhide YAMAMOTO, Yasuo YAMADA, Fumiyuki KUZE, Takako MURAYAMA, Katsuhiro SUZUKI, Motokazu KATO, Masaru CHIBA, Riyo YAMAGUCHI, Hitoshi NAGAI, Fumikazu UMEDA, Hiromi TOMIOKA, Osamu EBISUI, Hironobu IWASAKI, Kenji BANDO, Takashi NISHIMURA, Tatsuki OYAIZU, Sunao ISHIDA, Shunsaku OHSHIMA, Masao KADO, Hirotaka YASUBA, Kikuo SUGIMOTO, Seibun YONEZU, Yoshihiro UEDA, Kojiro YASUNAGA, Fumio MIKI, Eiro TSUBURA, Masaru NAKAGAWA, Takeshi OGURA, Fumitaka OGUSHI, Masashi KAWANISHI, Waka ICHIKAWA, Kazuhito MIZUNO, Seiko ISHIKAWA, Yoshihiro TAKISHITA, Hiroyasu BANDO, Yoshihiro HASHIMOTO, Nobuhiro NARITA, Masayoshi SAWAKI, Keiichi MIKASA, Mitsuru KONISHI, Toshiharu MATSUSHIMA, Makoto KIMURA, Masayasu KAWANISHI, Tadasu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Takao SASAKI, Yukio MATSUMOTO, Yuji SUGIMOTO, Yoshiro SAWAE, Toshiyuki ISHIMARU, Koji TAKAGI, Nobuyuki SHIMONO, Nobuaki SHIGEMATSU, Katsuro YAGAWA, Shinichiro HAYASHI, Kenji KONO, Keisuke ONUKI, Shinichi TOHARA, Seiji TAKEDA, Masahide TAKII, Katsumi OKUDAIRA, Akihiko SAKAUE, Koichi SHINOHARA, Kotaro OIZUMI, Yoichiro ICHIKAWA, Masashi KAWAHARA, Kohei HARA, Masaki HIROTA, Keizo YAMAGUCHI, Shigeru KONO, Hironobu KOGA, Mitsuo KAKU, Yasumasa DOTSU, Hiroshi YAMADA, Kiyoyasu FUKUSHIMA, Naofumi SUYAMA, Toshiaki HAYASHI, Keizo MATSUMOTO, Toshiaki YOSHIDA, Tsuyoshi NAGATAKE, Moritoshi AKIYAMA, Masakazu TAKASUGI, Mikio TAGUCHI, Kiwao WATANABE, Harumi SHISHIDO, Kiyoshi SHIMA, Shinobu TAKENAKA, Masaru NASU, Jun GOTO, Hideaki SHIGENO, Yoichiro GOTO, Takayoshi TASHIRO, Hiroyuki NAGAI, Toru YAMAZAKI, Mitsunobu AKASHI, Hiroshi FUKUHARA, Hiroshi KANESHIMA, Yuei IRABU, Katsuyoshi SHIMOJI, Keizo KITSUKAWA, Yoshiteru SHIGENO, Nobuya OGAWA

Publikováno v: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 65(4)

Efficacy and safety of a new injectable cephem antibiotic, cefpirome sulfate (hereafter, CPR), against respiratory tract infections were examined and compared with those of a control drug, ceftazidime (hereafter, CAZ). As a rule, CPR 0.5 g twice a da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99fe7d0ee55cd4624b5418f766ecc70
https://pubmed.ncbi.nlm.nih.gov/2071959

A Convenient Synthesis of Ethyl 3-(2,2-Dihaloethenyl)-2,2-dimethylcyclopropanecarboxylates and Its Modifications for cis-Isomer Enrichment

Autor: Yuriko Takahatake, Akira Negishi, Kiyoshi Kondo, Kikuo Sugimoto, Kiyohide Matsui, Toshiyuki Takashima, Tamotsu Fujimoto

Publikováno v: Bulletin of the Chemical Society of Japan. 59:221-227

A synthesis of the title compounds 5 involves the reaction between 3-methyl-2-buten-1-ol and triethyl orthoacetate to produce ethyl 3,3-dimethyl-4-pentenoate, which is followed by the addition of various carbon tetrahalides to the double bond. The re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d7903e11e4368df9dbb36bb439af008
https://doi.org/10.1246/bcsj.59.221

Comparison of HAPA-B and Amikacin in the Treatment of Respiratory Tract Infections

Autor: Hiroyuki KOBAYASHI, Hiroshi OSHITANI, Masahiko YOSHIDA, Akira SAITO, Ichiro NAKAYAMA, Sokichi ONODERA, Nobuhiro SASAKI, Fumio NAGAHAMA, Yomei HIRAGA, Takehito NAKABAYASHI, Kyuichiro SEKINE, Jutaro SHIMOMURA, Kazuo TAKEBE, Shiro KOSAKA, Mitsuo MASUDA, Seiichi MURAKAMI, Kenichi KIMURA, Hideaki KASHIWAMURA, Keiko GASA, Masao TAMURA, Kazuki KONISHI, Takashi ITO, Yoshikatsu NEMOTO, Hiroshi KURAMITSU, Kazutoshi GOMI, Izumi HAYASHI, Masataka KATSU, Hajime YAMAGATA, Minoru SATOH, Yasushi UEDA, Atsushi SAITO, Tadashi MIYAHARA, Junzaburo KABE, Koichiro KUDOH, Yasuyuki SANO, Michiko HAIDA, Terumi TAKAHASHI, Keita KASAHARA, Ippei FUJIMORI, Yoshio KOBAYASHI, Seiji MITA, Takeshi MITSUI, Takao OKUBO, Akira ITO, Shigeki ODAGIRI, Kaneo SUZUKI, Koou MUROHASHI, Osamu SEKINE, Yoshimaru USUDA, Nobuki AOKI, Kaoru OYAMA, Naohiro YAMASHITA, Saburo YANO, Kaoru SHIMOKATA, Yoshihiro SENDA, Yoshio TORII, Saizi YOSHII, Keisuke NISHIWAKI, Osamu KOHNOU, Masahito KATO, Joichi KATO, Hidekazu HANAKI, Toshihiko TAKEUCHI, Kikuo SUGIMOTO, Kazue SHIMADA, Takafumi FUKUNAGA, Kisao SATAKE, Hikaru OHTA, Toshio NISHIMURA, Michiro NAKASHIMA, Sadao IKEDA, Hidehiro NANBA, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Minoru YOSHIYAMA, Tooru HIRAGA, Akihito MURATA, Shigenori NAKAJIMA, Yasuo TSUYA, Hiroki UENISHI, Rinzo SOEJIMA, Hiroshi KAWANE, Yoshihito NIKI, Susumu YAGI, Masaru SUMI, Michiro YAMAKIDO, Akimitsu KAMITSUNA, Masakazu ITASAKA, Kenji HASEGAWA, Yoshiro SAWAE, Kaoru OKADA, Yukio KUMAGAI, Shinichiro HAYASHI, Nobuaki SHIGEMATSU, Hitoshi NAGANO, Chiharu KUBO, Masahito KARIYA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Kohei HARA, Keizo YAMAGUCHI, Yoshiteru SHIGENO, Shigeru KOHNO, Toshiyuki OE, Kiyo FUJITA, Yasuko UEDA, Kota KOHNO, Keizo MATSUMOTO, Toshiaki YOSHIDA, Kazunori OISHI, Shukuro ARAKI, Masayuki ANDO, Moritaka SUGA, Kiyoshi SHIMA, Yasutsugu FUKUDA, Katsumasa TOKUNAGA, Shinobu TAKENAKA, Sadanobu HIGUCHI, Ryuji FUJISE, Jiro TAMIYA, Yuichi MOTOZATO, Kiyotaka ITO, Kiyonori ITSUNO, Takehiko SAKURAMI, Kunio FUJISAKI

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 60:1184-1215

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be903cd82042bc0972fa965be4c395b
https://doi.org/10.11150/kansenshogakuzasshi1970.60.1184