Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kikuë, Tachibana"'
Autor:
Bart J. H. Dequeker, Matthias J. Scherr, Hugo B. Brandão, Johanna Gassler, Sean Powell, Imre Gaspar, Ilya M. Flyamer, Aleksandar Lalic, Wen Tang, Roman Stocsits, Iain F. Davidson, Jan-Michael Peters, Karl E. Duderstadt, Leonid A. Mirny, Kikuë Tachibana
Publikováno v:
Nature
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)1–3, which contribute to transcription, recombination and genomic stability4,5. Cohesin extrudes DNA into loops that are thought to lengthen until CTCF boundari
Autor:
Fabian M.P. Kaiser, Sarah Gruenbacher, Maria Roa Oyaga, Enzo Nio, Markus Jaritz, Qiong Sun, Wietske van der Zwaag, Emanuel Kreidl, Lydia M. Zopf, Virgil A.S.H. Dalm, Johan Pel, Carolin Gaiser, Rick van der Vliet, Lucas Wahl, André Rietman, Louisa Hill, Ines Leca, Gertjan Driessen, Charlie Laffeber, Alice Brooks, Peter D. Katsikis, Joyce H.G. Lebbink, Kikuë Tachibana, Mirjam van der Burg, Chris I. De Zeeuw, Aleksandra Badura, Meinrad Busslinger
Publikováno v:
Journal of Experimental Medicine. 220
Autor:
Fabian M.P. Kaiser, Sarah Gruenbacher, Maria Roa Oyaga, Enzo Nio, Markus Jaritz, Qiong Sun, Wietske van der Zwaag, Emanuel Kreidl, Lydia M. Zopf, Virgil A.S.H. Dalm, Johan Pel, Carolin Gaiser, Rick van der Vliet, Lucas Wahl, André Rietman, Louisa Hill, Ines Leca, Gertjan Driessen, Charlie Laffeber, Alice Brooks, Peter D. Katsikis, Joyce H.G. Lebbink, Kikuë Tachibana, Mirjam van der Burg, Chris I. De Zeeuw, Aleksandra Badura, Meinrad Busslinger
Publikováno v:
Journal of Experimental Medicine, 219(9). ROCKEFELLER UNIV PRESS
Journal of Experimental Medicine, 219(9). Rockefeller University Press
Journal of Experimental Medicine, 219(9):e20220498. Rockefeller University Press
Journal of Experimental Medicine, 219(9). Rockefeller University Press
Journal of Experimental Medicine, 219(9):e20220498. Rockefeller University Press
The genetic causes of primary antibody deficiencies and autism spectrum disorder (ASD) are largely unknown. Here, we report a patient with hypogammaglobulinemia and ASD who carries biallelic mutations in the transcription factor PAX5. A patient-speci
Autor:
Johanna Gassler, Wataru Kobayashi, Imre Gáspár, Siwat Ruangroengkulrith, Maximilian Kümmecke, Pavel Kravchenko, Maciej Zaczek, Antoine Vallot, Laura Gomez Hernandez, Laura Cuenca Rico, Sabrina Ladstätter, Kikuë Tachibana
Life begins with a switch in genetic control from the maternal to the embryonic genome during zygotic genome activation (ZGA) in totipotent embryos. Despite its importance, the essential regulators of ZGA remain largely unknown in mammals. Based on d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a852e90ecdae918579b3a2c53750cb21
https://doi.org/10.1101/2022.05.17.492379
https://doi.org/10.1101/2022.05.17.492379
Autor:
Sabrina Ladstätter, Kikuë Tachibana
Publikováno v:
The Journal of Cell Biology
Ladstätter and Tachibana discuss changes in DNA methylation, chromatin accessibility, and topological architecture occurring during the reprogramming to totipotency in the early embryo.
The early embryo is the natural prototype for the acquisit
The early embryo is the natural prototype for the acquisit
Autor:
Wataru Kobayashi, Kikuë Tachibana
Publikováno v:
Current Opinion in Structural Biology
After fertilization, the genome of the totipotent embryo is transcriptionally inactive and then initiates bursts of transcription termed zygotic genome activation (ZGA). Despite the fundamental importance of initiating an embryonic transcription prog
Autor:
Kikuë Tachibana, Sean Powell, Johanna Gassler, Mariana C C Silva, Emmanouella E. Chatzidaki, Bart J. H. Dequeker
Publikováno v:
Current Biology
The frequency of egg aneuploidy and trisomic pregnancies increases with maternal age. To what extent individual approaches can delay the "maternal age effect" is unclear because multiple causes contribute to chromosomal abnormalities in mammalian egg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2204fc68faf32f953954b517fde2a3fe
https://hdl.handle.net/21.11116/0000-0009-A01E-121.11116/0000-0009-A020-D21.11116/0000-0009-A021-C
https://hdl.handle.net/21.11116/0000-0009-A01E-121.11116/0000-0009-A020-D21.11116/0000-0009-A021-C
Autor:
Bart J H, Dequeker, Matthias J, Scherr, Hugo B, Brandão, Johanna, Gassler, Sean, Powell, Imre, Gaspar, Ilya M, Flyamer, Aleksandar, Lalic, Wen, Tang, Roman, Stocsits, Iain F, Davidson, Jan-Michael, Peters, Karl E, Duderstadt, Leonid A, Mirny, Kikuë, Tachibana
Publikováno v:
Nature. 606(7912)
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)
Autor:
Qing-Yuan Sun, Wan Kin Au Yeung, Zili Lin, Yujie Sun, Aibin He, Nathalie Véron, Hui Zheng, Bo Huang, Kikuë Tachibana, Ling Liu, Hiroyuki Sasaki, Antoine H.F.M. Peters, Peizhe Wang, Wei Xie, Qiujun Wang, Yumiko K Kawamura, Zhenhai Du, Evgeniy A. Ozonov, Kai Xu, Ke Zhang, Sean Powell, Jie Na, Guang Yu, Lijia Li, Qian Zhou, Lei Chang, Johanna Gassler, Qianhua Xu
Publikováno v:
Molecular Cell
Summary In mammals, chromatin organization undergoes drastic reorganization during oocyte development. However, the dynamics of three-dimensional chromatin structure in this process is poorly characterized. Using low-input Hi-C (genome-wide chromatin
Autor:
Matthias Merkenschlager, Minna U. Kaikkonen, Sergi Cuartero, Felix D. Weiss, Henri Niskanen, Gioacchino Natoli, Elizabeth Ing-Simmons, Irene Robles-Rebollo, Iros Barozzi, Robin D. Dowell, Silvia Masella, Kikuë Tachibana, Boris Lenhard, Amanda G. Fisher, Mariane Tami Amano, Xiaolin Xiao, Enrico Petretto, Ya Guo, Kim Nasmyth, Yi Fang Wang, Dounia Djeghloul, Gopuraja Dharmalingam
Publikováno v:
Nature immunology
Nature Immunology
Nature Immunology
Cohesin is important for 3-dimensional (3D) genome organization. Nevertheless, even the complete removal of cohesin has surprisingly little impact on steady-state gene transcription and enhancer activity. Here we show that cohesin was required for th