Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kikoh Obi"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1451-1454
A series of novel nikkomycin analogue inhibitors of the chitin synthase of fungal cell wall was synthesized and evaluated for their inhibitory activities. Among them, the compound having a phenanthrene group at the terminal amino acid was found to po
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2777-2782
Synthesis and biological properties of a novel class of cephalosporins with a 2-[5-(3-hydroxy-4-pyridon-6-yl)1,3,4-oxadiazol-2-yl]thioethyl group at C-7 position are described. Among them, the compounds having a pyridiniumthiomethyl group at C-3 posi
Publikováno v:
ChemInform. 27
Synthesis and biological properties of a novel class of cephalosporins with a 2-[5-(3-hydroxy-4-pyridon-6-yl)1,3,4-oxadiazol-2-yl]thioethyl group at C-7 position are described. Among them, the compounds having a pyridiniumthiomethyl group at C-3 posi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:917-924
Various structural types of monobactams bearing an (R)-1-hydroxyethyl and an (S)-1-carbamoyloxyethyl group at the C 3,4 -positions, respectively, could be synthesized from (3S,4S)-4-[(S)-1-benzyloxyethyl]-3-[(R)-1-hydroxyethyl]-2-azetidinone. These s
Publikováno v:
ChemInform. 31
A series of novel nikkomycin analogue inhibitors of the chitin synthase of fungal cell wall was synthesized and evaluated for their inhibitory activities. Among them, the compound having a phenanthrene group at the terminal amino acid was found to po
Publikováno v:
Nucleic acids symposium series. (42)
A series of novel nikkomycin analogs, which inhibited chitin synthase, the fungal cell wall biosynthesis enzyme, has been synthesized and evaluated their inhibitory activities.
Publikováno v:
The Journal of antibiotics. 48(3)
Publikováno v:
The Journal of antibiotics. 48(3)
Publikováno v:
Tetrahedron Letters. 28:87-90
Lithiation of 2′,3′,5′-tris- O -( tert -butyldimethylsilyl)uridine with sec -BuLi/TMEDA occurs at the C-5 position with a high regioselectivity and subsequent reactions of the resulting C-5 lithiated species with a variety of electrophiles prov
Publikováno v:
Tetrahedron. 42:4187-4195
phenylthio group at the C-6 position of uridine serves as the protecting group during lithiation at the C-5 position with lithium 2,2,6,6-tetramethylpiperidide. Reactions of the resulting C-5 lithiated species with various types of electrophiles furn