Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kijung Sung"'
Autor:
Yingli Gu, Flora Guerra, Mingzheng Hu, Alexander Pope, Kijung Sung, Wanlin Yang, Simone Jetha, Thomas A. Shoff, Tessanya Gunatilake, Owen Dahlkamp, Linda Zhixia Shi, Fiore Manganelli, Maria Nolano, Yue Zhou, Jianqing Ding, Cecilia Bucci, Chengbiao Wu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The Rab7V162M mutation associated with Charcot Marie Tooth 2B peripheral neuropathy causes mitochondrial fragmentation in patient-derived fibroblasts and primary cultured dorsal root ganglion sensory neurons from E18 mouse embryos.
Externí odkaz:
https://doaj.org/article/ff7f26e091d241bdb1ca3d45ed50c24d
Autor:
Suzhen Lin, André D.G. Leitão, Savannah Fang, Yingli Gu, Sophia Barber, Rhiannon Gilliard-Telefoni, Alfredo Castro, Kijung Sung, Ruinan Shen, Jazmin B. Florio, Michael L. Mante, Jianqing Ding, Brian Spencer, Eliezer Masliah, Robert A. Rissman, Chengbiao Wu
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 106010- (2023)
Mutations or triplication of the alpha synuclein (ASYN) gene contribute to synucleinopathies including Parkinson's disease (PD), Dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). Recent evidence suggests that ASYN also plays an impor
Externí odkaz:
https://doaj.org/article/ce172def23994913ad183ff932d3046b
Autor:
Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-19 (2020)
Abstract Background In Alzheimer’s Disease (AD), about one-third of the risk genes identified by GWAS encode proteins that function predominantly in the endocytic pathways. Among them, the Ras and Rab Interactor 3(RIN3) is a guanine nucleotide exch
Externí odkaz:
https://doaj.org/article/fba437dace9840c482d15ffe0b14536d
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 4, Pp 570-573 (2019)
Nerve growth factor (NGF) is a powerful trophic factor that provides essential support for the survival and differentiation of sympathetic and sensory neurons during development. However, NGF also activates nociceptors contributing significantly to i
Externí odkaz:
https://doaj.org/article/7321ae420fbd441b84800b5f4ad76d73
Autor:
Veronica Gomez Godinez, Vikash Morar, Christopher Carmona, Yingli Gu, Kijung Sung, Linda Z. Shi, Chengbiao Wu, Daryl Preece, Michael W. Berns
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Laser-induced shockwaves (LIS) can be utilized as a method to subject cells to conditions similar to those occurring during a blast-induced traumatic brain injury. The pairing of LIS with genetically encoded biosensors allows researchers to monitor t
Externí odkaz:
https://doaj.org/article/920ee3d1862a49d794d75ff90d2dab8c
Autor:
Fang Fang, Wanlin Yang, Jazmin B. Florio, Edward Rockenstein, Brian Spencer, Xavier M. Orain, Stephanie X. Dong, Huayan Li, Xuqiao Chen, Kijung Sung, Robert A. Rissman, Eliezer Masliah, Jianqing Ding, Chengbiao Wu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Recent studies have demonstrated that hyperphosphorylation of tau protein plays a role in neuronal toxicities of α-synuclein (ASYN) in neurodegenerative disease such as familial Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) an
Externí odkaz:
https://doaj.org/article/12c01bf2810f488c9d8ecb8510422e17
Autor:
Wanlin Yang, Kijung Sung, Fengli Zhou, Wei Xu, Robert A. Rissman, Jianqing Ding, Chengbiao Wu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Nerve growth factor (NGF) exerts multifaceted functions through different stages of life. A missense mutation (R100W) in the beta-NGF gene was found in hereditary sensory autonomic neuropathy V (HSAN V) patients with severe loss of pain perception bu
Externí odkaz:
https://doaj.org/article/adec7960054d455f8f3166af55f92b01
Autor:
Kai Zhang, Liting Duan, Qunxiang Ong, Ziliang Lin, Pooja Mahendra Varman, Kijung Sung, Bianxiao Cui
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92917 (2014)
It has been proposed that differential activation kinetics allows cells to use a common set of signaling pathways to specify distinct cellular outcomes. For example, nerve growth factor (NGF) and epidermal growth factor (EGF) induce different activat
Externí odkaz:
https://doaj.org/article/8969fb8f6414437e944cb5bb8a7329bb
Autor:
Chengbiao Wu, Robert A. Rissman, Ruinan Shen, Wei Xu, Kijung Sung, Wanlin Yang, Suzhen Lin, Ming Lei, Lu He, Xiaobei Zhao, Yongbo Ding, Brian Spencer, Savannah Fang, Jianqing Ding
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-19 (2020)
Translational Neurodegeneration
Translational Neurodegeneration
BackgroundIn Alzheimer’s Disease (AD), about one-third of the risk genes identified by GWAS encode proteins that function predominantly in the endocytic pathways. Among them, the Ras and Rab Interactor 3(RIN3) is a guanine nucleotide exchange facto
Autor:
Veronica Gomez Godinez, Christopher Carmona, Chengbiao Wu, Daryl Preece, Kijung Sung, Vikash Morar, Linda Z. Shi, Yingli Gu, Michael W. Berns
Publikováno v:
Optical Trapping and Optical Micromanipulation XVIII.
Laser induced shockwave (LIS) can be utilized to subject neuronal cells to conditions similar to those occurring during a blast induced traumatic brain injury. We utilized a 532nm Coherent Flare laser to induce a shockwave near cells which had been t