Zobrazeno 1 - 10
of 469
pro vyhledávání: '"Kiichi Ishiwata"'
Autor:
Jun Toyohara, Norihiro Harada, Takeharu Kakiuchi, Hiroyuki Ohba, Masakatsu Kanazawa, Tetsuro Tago, Muneyuki Sakata, Kiichi Ishiwata
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Introduction Increases in fasting plasma glucose (PG) levels lead to a decrease in 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) uptake in the normal brain, especially in the precuneus, resulting in an Alzheimer’s disease (AD)-like uptake pat
Externí odkaz:
https://doaj.org/article/671d05d5fcbf4c1580a1773191a3374d
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 14, Iss 1, Pp 1-9 (2017)
Abstract Background Physical activity may preserve neuronal plasticity, increase synapse formation, and cause the release of hormonal factors that promote neurogenesis and neuronal function. Previous studies have reported enhanced neurocognitive func
Externí odkaz:
https://doaj.org/article/361e9363c0f848f49a1a1508dcfb4ba4
Publikováno v:
NeuroImage: Clinical, Vol 22, Iss , Pp - (2019)
Imaging of type 1 metabotropic glutamate receptor (mGluR1) has recently become possible using positron emission tomography (PET). To date, little evidence exists on the role of mGluR1 in the pathophysiology of Alzheimer's disease (AD). We aimed to ex
Externí odkaz:
https://doaj.org/article/f681bff4489e4bdfadc916280a70546d
Autor:
Masahiro Mishina, Yuichi Kimura, Muneyuki Sakata, Kenji Ishii, Keiichi Oda, Jun Toyohara, Kazumi Kimura, Kiichi Ishiwata
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Adenosine A1 receptors (A1Rs) are widely distributed throughout the entire human brain, while adenosine A2A receptors (A2ARs) are present in dopamine-rich areas of the brain, such as the basal ganglia. A past study using autoradiography reported a re
Externí odkaz:
https://doaj.org/article/baaa4f876fca488898c5b13fd4940aba
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181400 (2017)
Increasing plasma glucose levels and insulin resistance can alter the distribution pattern of fluorine-18-labeled fluorodeoxyglucose (18F-FDG) in the brain and relatively reduce 18F-FDG uptake in Alzheimer's disease (AD)-related hypometabolic regions
Externí odkaz:
https://doaj.org/article/85449293d2db4106a405c2e2cb434c4d
Autor:
Hideki Murai, Yukihisa Suzuki, Motohiro Kiyosawa, Masato Wakakura, Manabu Mochizuki, Kiichi Ishiwata, Kenji Ishii
Publikováno v:
Case Reports in Ophthalmology, Vol 2, Iss 1, Pp 50-54 (2011)
A 43-year-old woman with drug-related blepharospasm was followed up for 22 months. She had undergone etizolam treatment for 19 years for indefinite complaints. We examined her cerebral glucose metabolism 5 times (between days 149 and 688 since presen
Externí odkaz:
https://doaj.org/article/f6c9d1b2ef914b649af703e4fd561c81
Autor:
Masahiro Mishina, Kiichi Ishiwata, Mika Naganawa, Yuichi Kimura, Shin Kitamura, Masahiko Suzuki, Masaya Hashimoto, Kenji Ishibashi, Keiichi Oda, Muneyuki Sakata, Makoto Hamamoto, Shiro Kobayashi, Yasuo Katayama, Kenji Ishii
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17338 (2011)
Adenosine A(2A) receptors (A2ARs) are thought to interact negatively with the dopamine D(2) receptor (D2R), so selective A2AR antagonists have attracted attention as novel treatments for Parkinson's disease (PD). However, no information about the rec
Externí odkaz:
https://doaj.org/article/069888551e134aa2826f234b749d242c
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17723 (2011)
The purpose of this study was to determine the binding sites of pramipexole in extrastriatal dopaminergic regions because its antidepressive effects have been speculated to occur by activating the dopamine D(2) receptor subfamily in extrastriatal are
Externí odkaz:
https://doaj.org/article/92f09f5432fe4685bb1223e089450a54
Autor:
Jun Toyohara, Kiichi Ishiwata, Muneyuki Sakata, Jin Wu, Shingo Nishiyama, Hideo Tsukada, Kenji Hashimoto
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e8961 (2010)
BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. The goal of this study was to evaluate the two carbon-11-labeled
Externí odkaz:
https://doaj.org/article/0de442a6025d4bf680719d77708c3e22
Publikováno v:
Movement Disorders. 37:853-857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a579d0a338c0beb6c8a0a4efdacd921
https://doi.org/10.1002/mds.28897
https://doi.org/10.1002/mds.28897