Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial

Autor: Cose Stephen, Webb Emily L, Jones Frances M, Kihembo Macklyn, Mawa Patrice A, Tweyongyere Robert, Dunne David W, Vennervald Birgitte J, Elliott Alison M

Publikováno v: BMC Infectious Diseases, Vol 11, Iss 1, p 234 (2011)

Abstract Background Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies. Praziquantel treatment during pregnancy boosts maternal immune resp

Externí odkaz: https://doaj.org/article/ffb4b037d17c4c469848d171112a7430

Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial

Autor: Webb, Emily L, Mawa, Patrice A, Ndibazza, Juliet, Kizito, Dennison, Namatovu, Alice, Kyosiimire-Lugemwa, Jacqueline, Nanteza, Bridget, Nampijja, Margaret, Muhangi, Lawrence, Woodburn, Patrick W, Akurut, Hellen, Mpairwe, Harriet, Akello, Miriam, Lyadda, Nancy, Bukusuba, Joseph, Kihembo, Macklyn, Kizza, Moses, Kizindo, Robert, Nabulime, Juliet, Ameke, Christine, Namujju, Proscovia B, Tweyongyere, Robert, Muwanga, Moses, Whitworth, James AG, Elliott, Alison M

Publikováno v: In The Lancet 2011 377(9759):52-62

Baseline Inflammatory Biomarkers Identify Subgroups of HIV-Infected African Children With Differing Responses to Antiretroviral Therapy

Autor: Prendergast, Andrew J, Szubert, Alexander J, Berejena, Chipo, Pimundu, Godfrey, Pala, Pietro, Shonhai, Annie, Musiime, Victor, Bwakura-Dangarembizi, Mutsa, Poulsom, Hannah, Hunter, Patricia, Musoke, Philippa, Kihembo, Macklyn, Munderi, Paula, Gibb, Diana M, Spyer, Moira, Walker, A Sarah, Klein, Nigel, ARROW Trial Team

BACKGROUND: Identifying determinants of morbidity and mortality may help target future interventions for human immunodeficiency virus (HIV)-infected children. METHODS: CD4(+) T-cell count, HIV viral load, and levels of biomarkers (C-reactive protein,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d78f4a700f534422babc573ae3d86dc8

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Baseline Inflammatory Biomarkers Identify Subgroups of HIV-Infected African Children With Differing Responses to Antiretroviral Therapy.

Autor: Prendergast AJ; Queen Mary University of London MRC Clinical Trials Unit at University College London., Szubert AJ; MRC Clinical Trials Unit at University College London., Berejena C; University of Zimbabwe, Harare., Pimundu G; Joint Clinical Research Centre., Pala P; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda., Shonhai A; University of Zimbabwe, Harare., Musiime V; Joint Clinical Research Centre Makerere University College of Health Sciences., Bwakura-Dangarembizi M; University of Zimbabwe, Harare., Poulsom H; Institute of Child Health, London, United Kingdom., Hunter P; Institute of Child Health, London, United Kingdom., Musoke P; Paediatric Infectious Diseases Clinic/Baylor-Uganda, Kampala., Kihembo M; Makerere University College of Health Sciences., Munderi P; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda., Gibb DM; MRC Clinical Trials Unit at University College London., Spyer M; MRC Clinical Trials Unit at University College London., Walker AS; MRC Clinical Trials Unit at University College London., Klein N; Institute of Child Health, London, United Kingdom.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2016 Jul 15; Vol. 214 (2), pp. 226-36. Date of Electronic Publication: 2016 May 18.