Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kiflai Bein"'
Autor:
Rahel L. Birru, Kiflai Bein, Natalya Bondarchuk, Heather Wells, Qiao Lin, Y. Peter Di, George D. Leikauf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Bacterial infections contribute to accelerated progression and severity of chronic obstructive pulmonary disease (COPD). Apples have been associated with reduced symptoms of COPD and disease development due to their polyphenolic content. We examined
Externí odkaz:
https://doaj.org/article/c275396338c84690accb4415177b20fa
Autor:
Kiflai Bein, Rahel L. Birru, Heather Wells, Theodore P. Larkin, Tengziyi Ge, George D. Leikauf
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Abstract Acrolein is a reactive inhalation hazard. Acrolein’s initial interaction, which in itself can be function‐altering, is followed by time‐dependent cascade of complex cellular and pulmonary responses that dictate the severity of the inju
Externí odkaz:
https://doaj.org/article/f98e3b9dc39145f594c1e83793f09a3d
Autor:
George D. Leikauf, Rahel L. Birru, Heather Wells, Kiflai Bein, Y. Peter Di, Qiao Lin, Natalya Bondarchuk
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
Bacterial infections contribute to accelerated progression and severity of chronic obstructive pulmonary disease (COPD). Apples have been associated with reduced symptoms of COPD and disease development due to their polyphenolic content. We examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb98fbea0adf3aa0845ead0ca96bf87
https://www.frontiersin.org/articles/10.3389/fcimb.2021.652944/full
https://www.frontiersin.org/articles/10.3389/fcimb.2021.652944/full
Autor:
Tengziyi Ge, Kiflai Bein, Theodore P. Larkin, Rahel L. Birru, Heather Wells, George D. Leikauf
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
Acrolein is a reactive inhalation hazard. Acrolein’s initial interaction, which in itself can be function‐altering, is followed by time‐dependent cascade of complex cellular and pulmonary responses that dictate the severity of the injury. To in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60203537a2e72a70b772b08459f308f
https://doaj.org/article/f98e3b9dc39145f594c1e83793f09a3d
https://doaj.org/article/f98e3b9dc39145f594c1e83793f09a3d
Autor:
Louis J. Vuga, Y. Peter Di, Koustav Ganguly, Daniel R. Prows, Timothy M. Martin, Kelly A. Brant, Eleazar Eskin, James P. Fabisiak, Ann-Soo Jang, Naftali Kaminski, Kiflai Bein, Emrah Kostem, George D. Leikauf, Vincent J. Concel, Swapna Upadhyay
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
In this study, a genetically diverse panel of 43 mouse strains was exposed to ammonia, and genome-wide association mapping was performed employing a single-nucleotide polymorphism (SNP) assembly. Transcriptomic analysis was used to help resolve the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d5957f24619cb0930c5bc6c8b49fa6
https://europepmc.org/articles/PMC7847062/
https://europepmc.org/articles/PMC7847062/
Autor:
Rahel L. Birru, Theodore P. Larkin, Matthew V. Fagerburg, Xuemei Zeng, George D. Leikauf, Kiflai Bein, Pamela S. Cantrell, Heather Wells
Publikováno v:
Chemical research in toxicology. 33(7)
Albumin is an abundant protein in the lung lining fluid that forms an interface between lung epithelial cells and the external environment. In the lung, albumin can be targeted for adduction by inhaled acrolein. Acrolein, an α,β-unsaturated aldehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601904fa4239ee4ff4b00630fba73cf8
https://pubmed.ncbi.nlm.nih.gov/32530271
https://pubmed.ncbi.nlm.nih.gov/32530271
Autor:
Yuanpu Peter Di, Kiflai Bein, Aaron Barchowsky, Natalya Bondarchuk, George D. Leikauf, Rahel L. Birru, Heather Wells
Publikováno v:
Mol Nutr Food Res
Scope Bacterial infection induces mucus overproduction, contributing to acute exacerbations and lung function decline in chronic respiratory diseases. A diet enriched in apples may provide protection from pulmonary disease development and progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680bf0e308e58205168d94d4356d83e0
https://doi.org/10.1002/mnfr.202000658
https://doi.org/10.1002/mnfr.202000658
Autor:
Danny C. Alexander, Kiflai Bein, Jonathan E. McDunn, Vincent J. Concel, Annerose Berndt, An Soo Jang, Naftali Kaminski, Hannah Pope-Varsalona, Zhen Hu, Louis J. Vuga, Swapna Upadhyay, Mario Medvedovic, Kelly A. Brant, James P. Fabisiak, George D. Leikauf, Richard A. Dopico, Koustav Ganguly, Qian Li
Publikováno v:
Molecular Nutrition & Food Research. 55:1423-1434
This investigation sought to better understand the metabolic role of the lung and to generate insights into the pathogenesis of acrolein-induced acute lung injury. A respiratory irritant, acrolein is generated by overheating cooking oils or by domest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae13cc11bbc2599ddb255476efb6acfb
https://doi.org/10.1002/mnfr.201100291
https://doi.org/10.1002/mnfr.201100291
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 45:436-444
The murine surfactant-associated protein B (Sftpb) gene promoter, spanning nucleotides −653 to +42, is composed of functionally distinct proximal and distal regions. Although both regions contain consensus/putative activator protein 1 (AP-1) sites,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21e6214ec16223b2421886e41fa5a1e
https://doi.org/10.1165/rcmb.2010-0260oc
https://doi.org/10.1165/rcmb.2010-0260oc
Publikováno v:
American Journal of Physiology-Cell Physiology. 287:C1012-C1022
The transforming growth factor (TGF) family of secretory polypeptides comprises signaling proteins involved in numerous physiological processes, including vascular development and vessel wall integrity. Both pro- and anti-angiogenic effects of TGF-β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f1bb957ae0bec669a5aaeabb4a1092
https://doi.org/10.1152/ajpcell.00101.2004
https://doi.org/10.1152/ajpcell.00101.2004