Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kieu Trinh Do"'
Autor:
Uwe Piontek, Henri Wallaschofski, Gabi Kastenmüller, Karsten Suhre, Henry Völzke, Kieu Trinh Do, Anna Artati, Matthias Nauck, Jerzy Adamski, Nele Friedrich, Maik Pietzner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The role of androgens in metabolism with respect to sex-specific disease associations is poorly understood. Therefore, we aimed to provide molecular signatures in plasma and urine of androgen action in a sex-specific manner using state-of-th
Externí odkaz:
https://doaj.org/article/e1e50af573bf4acd84e0bfe53cf0796c
Autor:
Eva C Schulte, Elisabeth Altmaier, Hannah S Berger, Kieu Trinh Do, Gabi Kastenmüller, Simone Wahl, Jerzy Adamski, Annette Peters, Jan Krumsiek, Karsten Suhre, Bernhard Haslinger, Andres Ceballos-Baumann, Christian Gieger, Juliane Winkelmann
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147129 (2016)
Serum metabolite profiling can be used to identify pathways involved in the pathogenesis of and potential biomarkers for a given disease. Both restless legs syndrome (RLS) and Parkinson`s disease (PD) represent movement disorders for which currently
Externí odkaz:
https://doaj.org/article/2c54683c5a174d4d8a735b718b0d2901
Autor:
Jerzy Adamski, Sophie Molnos, Simone Wahl, Annette Peters, Konstantin Strauch, Isobel D. Stewart, Claudia Langenberg, Michael Laimighofer, Christian Gieger, Harald Grallert, Karsten Suhre, Gabi Kastenmüller, Fabian J. Theis, Jan Krumsiek, Johannes Raffler, Kieu Trinh Do
Publikováno v:
Metabolomics
Metabolomics 14:128 (2018)
Metabolomics 14:128 (2018)
BACKGROUNDUntargeted mass spectrometry (MS)-based metabolomics data often contain missing values that reduce statistical power and can introduce bias in epidemiological studies. However, a systematic assessment of the various sources of missing value
Publikováno v:
Bioinformatics
Bioinformatics 35, 532-534 (2019)
Bioinformatics 35, 532-534 (2019)
Summary Associations of metabolomics data with phenotypic outcomes are expected to span functional modules, which are defined as sets of correlating metabolites that are coordinately regulated. Moreover, these associations occur at different scales,
Autor:
Christian Gieger, Fabian J. Theis, Matthias Nauck, Thomas Illig, Jan Krumsiek, Florian Kronenberg, Jerzy Adamski, Kieu Trinh Do, Nele Friedrich, Annette Peters, Dennis O. Mook-Kanamori, Ferdinand Stückler, Karsten Suhre, Kirstin Mittelstrass, Maik Pietzner, Harald Grallert, Janina S. Ried, Gabi Kastenmüller
Publikováno v:
Metabolomics 11, 1815-1833 (2015)
Metabolomics
Metabolomics
The susceptibility for various diseases as well as the response to treatments differ considerably between men and women. As a basis for a gender-specific personalized healthcare, an extensive characterization of the molecular differences between the
Autor:
Kieu Trinh Do, Maik Pietzner, Gabi Kastenmüller, Thomas Kocher, David J N P Rasp, Dennis O. Mook-Kanamori, Karsten Suhre, Matthias Nauck, Nele Friedrich, Jan Krumsiek
Publikováno v:
NPJ Syst. Biol. Appl. 3:28 (2017)
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-12 (2017)
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-12 (2017)
The identification of phenotype-driven network modules in complex, multifluid metabolomics data poses a considerable challenge for statistical analysis and result interpretation. This is the case for phenotypes with only few associations ('sparse' ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4882e47e8c57603087ef5a32461c0964
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=52005
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=52005
Akademický článek
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Autor:
Matthias Nauck, Maik Pietzner, Jerzy Adamski, Henrike Knacke, Uwe Völker, Nele Friedrich, Anna Artati, Werner Römisch-Margl, Karsten Suhre, Henri Wallaschofski, Jan Krumsiek, Henry Völzke, Gabi Kastenmüller, Kieu Trinh Do
Publikováno v:
The Journal of clinical endocrinology and metabolism. 101(12)
IGF-1 is known for its various physiological and severe pathophysiological effects on human metabolism; however, underlying molecular mechanisms still remain unsolved. To reveal possible molecular mechanisms mediating these effects, for the first tim
Autor:
Bernhard Haslinger, Juliane Winkelmann, Kieu Trinh Do, Andres O. Ceballos-Baumann, Christian Gieger, Eva C. Schulte, Gabi Kastenmüller, Karsten Suhre, Jan Krumsiek, Elisabeth Altmaier, Jerzy Adamski, Hannah S. Berger, Simone Wahl, Annette Peters
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147129 (2016)
PLoS ONE 11:e0147129 (2016)
PLoS ONE
PLoS ONE 11:e0147129 (2016)
PLoS ONE
BACKGROUND: Serum metabolite profiling can be used to identify pathways involved in the pathogenesis of and potential biomarkers for a given disease. Both restless legs syndrome (RLS) and Parkinson`s disease (PD) represent movement disorders for whic
Autor:
Fabian J. Theis, Kieu Trinh Do, Jan Krumsiek, Gabi Kastenmüller, Noha A. Yousri, Karsten Suhre, Dennis O. Mook-Kanamori
Publikováno v:
Journal of Proteome Research, 14(2), 1183-1194
Most studies investigating human metabolomics measurements are limited to a single biofluid, most often blood or urine. An organism's biochemical pool, however, comprises complex transboundary relationships, which can only be understood by investigat