Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kiersten Utsey"'
Autor:
Ahmed Elmokadem, Matthew Wiens, Timothy Knab, Kiersten Utsey, Samuel P. Callisto, Daniel Kirouac
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Population pharmacokinetic (PK) modeling serves as the cornerstone for understanding drug behavior within a specific population. It integrates subject covariates to elucidate the variability in PK parameters, thus enhancing predictive accura
Externí odkaz:
https://doaj.org/article/3d47c7519db54c2185941928d227783f
Autor:
Paolo F. Caimi, Mehdi Hamadani, Carmelo Carlo‐Stella, Masoud Nickaeen, Eric Jordie, Kiersten Utsey, Tim Knab, Francesca Zammarchi, Danilo Cucchi, Serafino Pantano, Karin Havenith, Ying Wang, Joseph Boni
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 76-83 (2024)
Abstract CD19‐targeting treatments have shown promise in relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL). Loncastuximab tesirine (loncastuximab tesirine‐lpyl [Lonca]) is a CD19‐targeting antibody‐drug conjugate indicated for
Externí odkaz:
https://doaj.org/article/9167f8b147204d32b3fe262991498192
Autor:
Kiersten Utsey, James P Keener
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1007689 (2020)
Millions of people worldwide develop foodborne illnesses caused by Salmonella enterica (S. enterica) every year. The pathogenesis of S. enterica depends on flagella, which are appendages that the bacteria use to move through the environment. Interest
Externí odkaz:
https://doaj.org/article/e61950a04096417d9cd82ed8631b88b3
Autor:
Paolo F. Caimi, Mehdi Hamadani, Carmelo Carlo-Stella, Masoud Nickaeen, Eric Jordie, Kiersten Utsey, Tim Knab, Francesca Zammarchi, Serafino Pantano, Karin Havenith, Ying Wang, Joseph Boni
Publikováno v:
Blood. 140:9548-9550
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa738b4aa88019808e870626546ffd7
https://doi.org/10.1182/blood-2022-159626
https://doi.org/10.1182/blood-2022-159626
Autor:
Kiersten Utsey, James P. Keener
Publikováno v:
Bulletin of Mathematical Biology. 82
DNA methylation is an essential epigenetic mechanism used by cells to regulate gene expression. Interestingly, DNA replication, a function necessary for cell division, disrupts the methylation pattern. Since perturbed methylation patterns are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4a1c083d202a847a8b983bbe85c34f
https://doi.org/10.1007/s11538-020-00765-4
https://doi.org/10.1007/s11538-020-00765-4
Autor:
Sean Russell, Ahmed Elmokadem, Madeleine S Gastonguay, Matthew M Riggs, Reed Freling, Kiersten Utsey
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 48(10)
Tissue:plasma partition coefficients are key parameters in physiologically based pharmacokinetic (PBPK) models, yet the coefficients are challenging to measure in vivo. Several mechanistic-based equations have been developed to predict partition coef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579fac56819d43a83d0e288df2e8fb8b
https://pubmed.ncbi.nlm.nih.gov/32665416
https://pubmed.ncbi.nlm.nih.gov/32665416