Výsledky vyhledávání - "Kiersten M. Gressani"

Prenatal Toxicity and Lack of Carcinogenicity of 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) following Transplacental Exposure

Autor: Alan J. Townsend, Kiersten M. Gressani, Mark Steven Miller, M. Gerard O'Sullivan, Sandra Leone-Kabler

Publikováno v: Toxicological Sciences. 55:407-414

Accumulating evidence from human and experimental animal studies indicates that consumption of heterocyclic amines (HA), derived from cooked meat and fish, may be associated with an increased incidence of cancer. Experiments were initiated to assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3496ef096838d19803c90787d57dc8
https://doi.org/10.1093/toxsci/55.2.407

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DIFFERENTIAL SENSITIVITY TO LUNG TUMORIGENESIS FOLLOWING TRANSPLACENTAL EXPOSURE OF MICE TO POLYCYCLIC HYDROCARBONS, HETEROCYCLIC AMINES, AND LUNG TUMOR PROMOTERS

Autor: Kiersten M. Gressani, Malkinson Am, Mark Steven Miller, Alan J. Townsend, Sandra Leone-Kabler, O'Sullivan Mg

Publikováno v: Experimental Lung Research. 26:709-730

Research conducted by this laboratory over the past decade has demonstrated the high susceptibility of the fetus to lung tumor formation following in utero exposure of the resistant C57BL/6 and DBA/2N strains of mice to 3-methylcholanthrene (MC). In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1971e04702680d31da48ea531f76da1
https://doi.org/10.1080/01902140150216774

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Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene

Autor: Alvin M. Malkinson, L. Douglas Case, M. Gerard O'Sullivan, Kiersten M. Gressani, Sandra Leone-Kabler, Mark Steven Miller

Publikováno v: Carcinogenesis. 20:2159-2165

The carcinogenic effects of in utero exposure to 3-methyl-cholanthrene (MC) have been demonstrated in the tumor-resistant C57BL/6 (B6) and DBA (D2) strains of mice. In this study, we determined the effects of in utero exposure to MC in BALB/c mice, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037a7f67dbccd54b9941f1516d502ea6
https://doi.org/10.1093/carcin/20.11.2159

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Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene

Autor: Sandra Leone-Kabler, L A Rollins, J M Cline, M S Miller, Kiersten M. Gressani

Publikováno v: Carcinogenesis. 19:1045-1052

An understanding of the basic mechanisms responsible for the pathogenesis of liver neoplasms is needed in order to develop better therapeutic strategies. The present study utilized a pharmacogenetic mouse model to assess the role of cytochrome P4501A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410ebc9c777ed9540919159f12c36eed
https://doi.org/10.1093/carcin/19.6.1045

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