Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kierra S. Hardy"'
Autor:
Kierra S. Hardy, Amanda N. Tuckey, Phoibe Renema, Mita Patel, Abu-Bakr Al-Mehdi, Domenico Spadafora, Cody A. Schlumpf, Robert A. Barrington, Mikhail F. Alexeyev, Troy Stevens, Jean-Francois Pittet, Brant M. Wagener, Jon D. Simmons, Diego F. Alvarez, Jonathon P. Audia
Publikováno v:
Toxins, Vol 14, Iss 2, p 152 (2022)
The Gram-negative, opportunistic pathogen Pseudomonas aeruginosa utilizes a type III secretion system to inject exoenzyme effectors into a target host cell. Of the four best-studied exoenzymes, ExoU causes rapid cell damage and death. ExoU is a phosp
Externí odkaz:
https://doaj.org/article/c9f84dac36d44282a31de0221c698954
Publikováno v:
Toxins, Vol 13, Iss 12, p 880 (2021)
Pseudomonas aeruginosa is an opportunistic, Gram-negative pathogen and an important cause of hospital acquired infections, especially in immunocompromised patients. Highly virulent P. aeruginosa strains use a type III secretion system (T3SS) to injec
Externí odkaz:
https://doaj.org/article/476df39dae6449a3898e52b51f73b8b8
Autor:
Brant M. Wagener, Naseem Anjum, Sarah C. Christiaans, Morgan E. Banks, Jordan C. Parker, Adam T. Threet, Rashidra R. Walker, Kayla D. Isbell, Stephen A. Moser, Troy Stevens, Mikhail F. Alexeyev, Jonathon P. Audia, Wito Richter, Kierra S. Hardy, Lina Abou Saleh, Charity Morgan, Jean-François Pittet
Publikováno v:
Toxins, Vol 12, Iss 6, p 369 (2020)
Pseudomonas aeruginosa is an opportunistic pathogen that causes pneumonia in immunocompromised and intensive care unit (ICU) patients. During host infection, P. aeruginosa upregulates the type III secretion system (T3SS), which is used to intoxicate
Externí odkaz:
https://doaj.org/article/79899cf953824f7faf6eb5035ca2568e
Autor:
Rui Tong Quek, Kierra S. Hardy, Stephen G. Walker, Dan T. Nguyen, Taciani de Almeida Magalhães, Adrian Salic, Sujatha M. Gopalakrishnan, Pamela A. Silver, Timothy J. Mitchison
Publikováno v:
ACS Chemical Biology. 18:583-594
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47174a7a4a308856f7be52a23131c12a
https://doi.org/10.1021/acschembio.2c00908
https://doi.org/10.1021/acschembio.2c00908
Autor:
Rui Tong Quek, Kierra S. Hardy, Stephen G. Walker, Dan T. Nguyen, Taciani de Almeida Magalhães, Adrian Salic, Sujatha M. Gopalakrishnan, Pamela A. Silver, Timothy J. Mitchison
Biomolecular condensates formed by liquid-liquid phase separation have been implicated in multiple diseases. Modulation of condensate dynamics by small molecules has therapeutic potential, but so far, few condensate modulators have been disclosed. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c571743b23ccd1210e33633c6c8a240
https://doi.org/10.1101/2022.12.05.519191
https://doi.org/10.1101/2022.12.05.519191
Autor:
Nicole Housley, Phoibe Renema, Domenico Spadafora, Andrea L. Britain, Diego F. Alvarez, Grace Dunbar, Kierra S. Hardy, Naga S. Annamdevula, Silas J. Leavesley, Thomas C. Rich, Jonathon P. Audia
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 318:L1074-L1083
Activation of the inflammasome-caspase-1 axis in lung endothelial cells is emerging as a novel arm of the innate immune response to pneumonia and sepsis caused by Pseudomonas aeruginosa. Increased levels of circulating autacoids are hallmarks of pneu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e908c14d081cae3f0faf6d9c0575de19
https://doi.org/10.1152/ajplung.00185.2019
https://doi.org/10.1152/ajplung.00185.2019
Autor:
Kierra S. Hardy, Amanda N. Tuckey, Nicole A. Housley, Joel Andrews, Mita Patel, Abu-Bakr Al-Mehdi, Robert A. Barrington, Suzanne L. Cassel, Fayyaz S. Sutterwala, Jonathon P. Audia
Publikováno v:
Infection and Immunity. 90
Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that causes nosocomial pneumonia, urinary tract infections, and bacteremia. A hallmark of P. aeruginosa pathogenesis is disruption of host cell function by the type III secretion syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd1ad95b27819f55465138bff58deb6
https://doi.org/10.1128/iai.00470-21
https://doi.org/10.1128/iai.00470-21
Publikováno v:
Toxins
Pseudomonas aeruginosa is an opportunistic, Gram-negative pathogen and an important cause of hospital acquired infections, especially in immunocompromised patients. Highly virulent P. aeruginosa strains use a type III secretion system (T3SS) to injec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee0bc4137b4bdfbe2e7df755dd9a9539
https://pubmed.ncbi.nlm.nih.gov/34941717
https://pubmed.ncbi.nlm.nih.gov/34941717
Autor:
Adam T Threet, Kierra S. Hardy, Mikhail Alexeyev, Troy Stevens, Stephen A. Moser, Lina Abou Saleh, Brant M. Wagener, Kayla D. Isbell, Naseem Anjum, Charity J. Morgan, Rashidra R Walker, Jean-Francois Pittet, Wito Richter, Jordan C Parker, Morgan E. Banks, Jonathon P. Audia, Sarah C. Christiaans
Publikováno v:
Toxins
Volume 12
Issue 6
Toxins, Vol 12, Iss 369, p 369 (2020)
Volume 12
Issue 6
Toxins, Vol 12, Iss 369, p 369 (2020)
Pseudomonas aeruginosa is an opportunistic pathogen that causes pneumonia in immunocompromised and intensive care unit (ICU) patients. During host infection, P. aeruginosa upregulates the type III secretion system (T3SS), which is used to intoxicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83c254d243ce54d6685906e3a816677
Autor:
Phoibe, Renema, Kierra S, Hardy, Nicole, Housley, Grace, Dunbar, Naga, Annamdevula, Andrea, Britain, Domenico, Spadafora, Silas, Leavesley, Thomas, Rich, Jonathon P, Audia, Diego F, Alvarez
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Activation of the inflammasome-caspase-1 axis in lung endothelial cells is emerging as a novel arm of the innate immune response to pneumonia and sepsis caused by Pseudomonas aeruginosa. Increased levels of circulating autacoids are hallmarks of pneu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21b0e85f391a85ba9a82fd7fb96fe023
https://pubmed.ncbi.nlm.nih.gov/32186399
https://pubmed.ncbi.nlm.nih.gov/32186399