Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kieron M. G. O'Connell"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 850-860 (2012)
Two-directional synthesis represents an ideal strategy for the rapid elaboration of simple starting materials and their subsequent transformation into complex molecular architectures. As such, it is becoming recognised as an enabling technology for d
Externí odkaz:
https://doaj.org/article/66f7bee8b2514cfb82e51443b4f5b302
Autor:
Martin Welch, George P. C. Salmond, Kieron M. G. O'Connell, Hannah F. Sore, David R. Spring, James T. Hodgkinson
Publikováno v:
Angewandte Chemie. 125:10904-10932
Die Einfuhrung effizienter antibakterieller Therapien fur Infektionskrankheiten in der Mitte des 20. Jahrhunderts revolutionierte die klinische Praxis und erleichterte die Entwicklung der modernen Medizin. Viele potenziell lebensbedrohliche Erkrankun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b614c82c52750c89e6dc8a331cc039
https://doi.org/10.1002/ange.201209979
https://doi.org/10.1002/ange.201209979
Autor:
Richard J. Spandl, David R. Spring, Monica Diaz‐Gavilan, Gemma L. Thomas, Kieron M. G. O'Connell
Publikováno v:
Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications
Diversity-oriented synthesis (DOS), which describes the synthesis of structurally diverse collections of small molecules, was developed, in part, to address combinatorial chemistry's shortfalls. In this paper, we hope to give an indication of what ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd43098814d4e8f90a18dca32546e342
https://doi.org/10.1002/tcr.20144
https://doi.org/10.1002/tcr.20144
Publikováno v:
Synlett. 2012:298-300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d8e7752033deb775ea70db352ee6844
https://doi.org/10.1055/s-0031-1290116
https://doi.org/10.1055/s-0031-1290116
Autor:
Monica Diaz‐Gavilan, Warren R. J. D. Galloway, David R. Spring, James T. Hodkingson, Kieron M. G. O'Connell
Publikováno v:
Chem. Commun.. 46:776-778
A diversity-oriented synthesis involving a cascade sequence, taking linear aminoalkenes to polycyclic scaffolds reminiscent of natural alkaloids, is presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb280228e8e3ab66e4195320b42933bd
https://doi.org/10.1039/b917965h
https://doi.org/10.1039/b917965h
Autor:
Kieron M. G. O'Connell, George P. C. Salmond, David R. Spring, James T. Hodgkinson, Martin Welch, Hannah F. Sore
Publikováno v:
ChemInform. 44
The introduction of effective antibacterial therapies for infectious diseases in the mid-20th century completely revolutionized clinical practices and helped to facilitate the development of modern medicine. Many potentially life-threatening conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f59c90a3d4f155823f9f1481ea84b7
https://doi.org/10.1002/chin.201352236
https://doi.org/10.1002/chin.201352236
Publikováno v:
Diversity-Oriented Synthesis
In this chapter, the underlying ideas behind diversity-oriented synthesis are introduced. The relationship between diversity-oriented synthesis and combinatorial chemistry is discussed, and the rationale behind the use of diversity-oriented synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::745466ee89561c0e9b7f5e380c2f9285
https://doi.org/10.1002/9781118618110.ch1
https://doi.org/10.1002/9781118618110.ch1
Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials
Autor:
James T. Hodgkinson, Kieron M. G. O'Connell, George P. C. Salmond, David R. Spring, Hannah F. Sore, Martin Welch
Publikováno v:
Angewandte Chemie (International ed. in English). 52(41)
The introduction of effective antibacterial therapies for infectious diseases in the mid-20th century completely revolutionized clinical practices and helped to facilitate the development of modern medicine. Many potentially life-threatening conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5412e0a05e82527b9daed49c88f669eb
https://pubmed.ncbi.nlm.nih.gov/24038605
https://pubmed.ncbi.nlm.nih.gov/24038605
Autor:
Martin Welch, Noemi Bartolucci, Brett M. Ibbeson, David R. Spring, Warren R. J. D. Galloway, Martina Della Valle, James T. Hodgkinson, Bernardas Morkunas, Megan H. Wright, Kieron M. G. O'Connell
Publikováno v:
Organicbiomolecular chemistry. 10(42)
Pseudomonas aeruginosa is a notorious human pathogen associated with a range of life-threatening nosocomial infections. There is an increasing problem of antibiotic resistance in P. aeruginosa, highlighted by the emergence of multi-drug resistant str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f9ca2b18262d02e088c59fbcff6a90
https://pubmed.ncbi.nlm.nih.gov/23014532
https://pubmed.ncbi.nlm.nih.gov/23014532
Autor:
Kieron M. G. O'Connell, Warren R. J. D. Galloway, Brett M. Ibbeson, Albert Isidro-Llobet, Cornelius J. O'Connor, David R. Spring
Publikováno v:
ChemInform. 43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54b4aeae0381a946adf3282daf7c247e
https://doi.org/10.1002/chin.201226254
https://doi.org/10.1002/chin.201226254