Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo

Autor: Gramatica, Andrea, Schwarzer, Roland, Brantley, William, Varco-Merth, Benjamin, Sperber, Hannah S, Hull, Philip A, Montano, Mauricio, Migueles, Stephen A, Rosenthal, Danielle, Hogan, Louise E, Johnson, Jeffrey R, Packard, Thomas A, Grimmett, Zachary W, Herzig, Eytan, Besnard, Emilie, Nekorchuk, Michael, Hsiao, Feng, Deeks, Steven G, Snape, Michael, Kiernan, Bernard, Roan, Nadia R, Lifson, Jeffrey D, Estes, Jacob D, Picker, Louis J, Verdin, Eric, Krogan, Nevan J, Henrich, Timothy J, Connors, Mark, Ott, Melanie, Pillai, Satish K, Okoye, Afam A, Greene, Warner C

Publikováno v: Journal of virology, vol 95, iss 8

An ability to activate latent HIV-1 expression could benefit many HIV cure strategies, but the first generation of latency reversing agents (LRAs) has proven disappointing. We evaluated AKT/mTOR activators as a potential new class of LRAs. Two glycog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c96bfc76b3067e866fd0e6d104e76a52
https://escholarship.org/uc/item/2bs8r4br

WAR AND ZERO-SUM GAMES

Autor: KIERNAN, BERNARD P.

Publikováno v: The Virginia Quarterly Review, 1977 Jan 01. 53(1), 17-31.

Externí odkaz: https://www.jstor.org/stable/26435880

THE CONSERVATIVE ILLUSION

Autor: KIERNAN, BERNARD

Publikováno v: The Virginia Quarterly Review, 1983 Apr 01. 59(2), 208-222.

Externí odkaz: https://www.jstor.org/stable/26436650

The Soviet Union and the Developing Nations Roger E. Kanet

Autor: Kiernan, Bernard P.

Publikováno v: The American Political Science Review, 1976 Mar 01. 70(1), 280-282.

Externí odkaz: https://www.jstor.org/stable/1960417

Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo .

Autor: Gramatica A; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Schwarzer R; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Brantley W; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Varco-Merth B; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Sperber HS; Vitalant Research Institute, San Francisco, California, USA.; Free University of Berlin, Institute of Biochemistry, Berlin, Germany., Hull PA; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA., Montano M; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA., Migueles SA; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Rosenthal D; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Hogan LE; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Johnson JR; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, USA., Packard TA; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA., Grimmett ZW; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA., Herzig E; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Besnard E; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA., Nekorchuk M; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Hsiao F; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Urology, University of California, San Francisco, San Francisco, California, USA., Deeks SG; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Snape M; AMO Pharma Ltd., London, United Kingdom., Kiernan B; AMO Pharma Ltd., London, United Kingdom., Roan NR; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Urology, University of California, San Francisco, San Francisco, California, USA., Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Estes JD; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Verdin E; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA., Krogan NJ; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, USA., Henrich TJ; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Connors M; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Ott M; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA., Pillai SK; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.; Vitalant Research Institute, San Francisco, California, USA., Okoye AA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA warner.greene@gladstone.ucsf.edu okoyea@ohsu.edu., Greene WC; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, California, USA warner.greene@gladstone.ucsf.edu okoyea@ohsu.edu.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.

Publikováno v: Journal of virology [J Virol] 2021 Mar 25; Vol. 95 (8). Date of Electronic Publication: 2021 Feb 03.