Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kieran P. Normoyle"'
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 77 (2024)
GABA, the primary inhibitory neurotransmitter, stimulates GABAA receptors (GABAARs) to increase the chloride conductance of the cytosolic membrane. The driving forces for membrane chloride currents are determined by the local differences between intr
Externí odkaz:
https://doaj.org/article/a68879ae5f58441d972bfa05f88743dc
THERMAL REGULATION OF THE BRAIN -AN ANATOMICAL AND PHYSIOLOGICAL REVIEW FOR CLINICAL NEUROSCIENTISTS
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2016)
Humans, like all mammals and birds, maintain a nearly constant core body temperature (36 -37.5°C) over a wide range of environmental conditions and are thus referred to as endotherms. The evolution of the brain and its supporting structures in mamma
Externí odkaz:
https://doaj.org/article/112e3c633888488983093ab94576548c
Publikováno v:
Translational Neuroscience, Vol 6, Iss 1, Pp 179-186 (2015)
Translational Neuroscience
Translational Neuroscience
Traumatic brain injury (TBI) is a multifaceted disease with intrinsically complex heterogeneity and remains a significant clinical challenge to manage. TBI model systems have demonstrated many mechanisms that contribute to brain parenchymal cell deat
Autor:
Catherine Best, Rose Du, Kevin Spitler, Kevin S. Jackson, Bonnie H. Wang, Daniel A. Llano, Huan Wang, Matthew F. Sharrock, Claire M. Miller, Kieran P. Normoyle
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
Frontiers in Neuroscience
Frontiers in Neuroscience
Brain temperature, as an independent therapeutic target variable, has received increasingly intense clinical attention. To date, brain hypothermia represents the most potent neuroprotectant in laboratory studies. Although the impact of brain temperat
Publikováno v:
Journal of Neurological Disorders.
While Chiari I malformation is a relatively common finding on MRI imaging, the vast majority of patients are asymptomatic and those who do present typically follow a slow course of chronic or subacute progression of symptoms. Emergent deterioration o
Autor:
William M. Brieher, Kieran P. Normoyle
Publikováno v:
The Journal of biological chemistry. 287(42)
Fast actin depolymerization is necessary for cells to rapidly reorganize actin filament networks. Utilizing a Listeria fluorescent actin comet tail assay to monitor actin disassembly rates, we observed that although a mixture of actin disassembly fac