Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kieran Didi"'
Autor:
Aidan P. Tay, Kieran Didi, Anuradha Wickramarachchi, Denis C. Bauer, Laurence O. W. Wilson, Maciej Maselko
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
DNA sequences of nearly any desired composition, length, and function can be synthesized to alter the biology of an organism for purposes ranging from the bioproduction of therapeutic compounds to invasive pest control. Yet despite offering many grea
Externí odkaz:
https://doaj.org/article/d195ba5dfb374237bf133e4ffee8395c
Autor:
William E. Arter, Runzhang Qi, Nadia A. Erkamp, Georg Krainer, Kieran Didi, Timothy J. Welsh, Julia Acker, Jonathan Nixon-Abell, Seema Qamar, Jordina Guillén-Boixet, Titus M. Franzmann, David Kuster, Anthony A. Hyman, Alexander Borodavka, Peter St George-Hyslop, Simon Alberti, Tuomas P. J. Knowles
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
A central concept for characterising phase-separating systems is the phase diagram but generation of such diagrams for biomolecular systems is typically slow and low-throughput. Here the authors describe PhaseScan, a combinatorial droplet microfluidi
Externí odkaz:
https://doaj.org/article/21a365c2a2af4ba08de716204af10bed
Autor:
Divyang Deep Tiwari, Nils Hoffmann, Kieran Didi, Sumukh Deshpande, Sucheta Ghosh, Tung V. N. Nguyen, Karthik Raman, Henning Hermjakob, Rahuman Sheriff
Machine learning (ML) models are widely used in life sciences and medicine; however, they are scattered across various platforms and there are several challenges that hinder their accessibility, reproducibility and reuse. In this manuscript, we prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aadc655034a209c15afd862b5350f5ce
https://doi.org/10.1101/2023.05.22.540599
https://doi.org/10.1101/2023.05.22.540599
Monoclonal antibodies have emerged as a key class of therapeutics, and nanobodies are rapidly increasing in popularity following the approval of the first nanobody drug in 2019, yet the therapeutic development of these biologics remains a challenge.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e16e9deb764154648e69b40c62ef438
https://doi.org/10.1101/2023.04.28.538712
https://doi.org/10.1101/2023.04.28.538712
Autor:
William E. Arter, Runzhang Qi, Nadia A. Erkamp, Georg Krainer, Kieran Didi, Timothy J. Welsh, Julia Acker, Jonathan Nixon-Abell, Seema Qamar, Jordina Guillén-Boixet, Titus M. Franzmann, David Kuster, Anthony A. Hyman, Alexander Borodavka, Peter St George-Hyslop, Simon Alberti, Tuomas P.J. Knowles
The assembly of intracellular proteins into biomolecular condensates via liquid-liquid phase separation (LLPS) has emerged as a fundamental process underlying the organisation and regulation of cellular space and function. Physicochemical characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac6976f2967a914f80474deb12ad53e
https://doi.org/10.1101/2020.06.04.132308
https://doi.org/10.1101/2020.06.04.132308