Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kieran A Boyle"'
Autor:
Kieran A Boyle, Erika Polgar, Maria Gutierrez-Mecinas, Allen C Dickie, Andrew H Cooper, Andrew M Bell, Evelline Jumolea, Adrian Casas-Benito, Masahiko Watanabe, David I Hughes, Gregory A Weir, John S Riddell, Andrew J Todd
Publikováno v:
eLife, Vol 12 (2023)
Somatosensory information is processed by a complex network of interneurons in the spinal dorsal horn. It has been reported that inhibitory interneurons that express neuropeptide Y (NPY), either permanently or during development, suppress mechanical
Externí odkaz:
https://doaj.org/article/0aaa87dba12840cf9be5bf7916875d41
Autor:
Kelly M Smith, Tyler J Browne, Olivia C Davis, A Coyle, Kieran A Boyle, Masahiko Watanabe, Sally A Dickinson, Jacqueline A Iredale, Mark A Gradwell, Phillip Jobling, Robert J Callister, Christopher V Dayas, David I Hughes, Brett A Graham
Publikováno v:
eLife, Vol 8 (2019)
Nociceptive information is relayed through the spinal cord dorsal horn, a critical area in sensory processing. The neuronal circuits in this region that underpin sensory perception must be clarified to better understand how dysfunction can lead to pa
Externí odkaz:
https://doaj.org/article/e0cd9725113d49e9aa0bf5e1f78d7155
Autor:
Raphaëlle Quillet, Maria Gutierrez-Mecinas, Erika Polgár, Allen C. Dickie, Kieran A. Boyle, Masahiko Watanabe, Andrew J. Todd
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The superficial dorsal horn (SDH) of the spinal cord contains a diverse array of neurons. The vast majority of these are interneurons, most of which are glutamatergic. These can be assigned to several populations, one of which is defined by expressio
Externí odkaz:
https://doaj.org/article/4d0a7cd44dd146b09de0df51daf423a2
Autor:
Wafa A. A. Alsulaiman, Raphaelle Quillet, Andrew M. Bell, Allen C. Dickie, Erika Polgár, Kieran A. Boyle, Masahiko Watanabe, R. Brian Roome, Artur Kania, Andrew J. Todd, Maria Gutierrez-Mecinas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract A recently developed Phox2a::Cre mouse line has been shown to capture anterolateral system (ALS) projection neurons. Here, we used this line to test whether Phox2a-positive cells represent a distinct subpopulation among lamina I ALS neurons.
Externí odkaz:
https://doaj.org/article/45445ef9894d49f187740e8e7d79332d
Autor:
Kieran A. Boyle, Erika Polgár, Maria Gutierrez-Mecinas, Allen C. Dickie, Andrew H. Cooper, Andrew M. Bell, M. Evelline Jumolea, Adrian Casas-Benito, Masahiko Watanabe, David I. Hughes, Greg A. Weir, John S. Riddell, Andrew J. Todd
Somatosensory information is processed by a complex network of interneurons in the spinal dorsal horn. It has been reported that inhibitory interneurons that express neuropeptide Y (NPY), either permanently or during development, suppress mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c86db481d4bfefadd400747f0b891e8
https://doi.org/10.1101/2023.02.10.528013
https://doi.org/10.1101/2023.02.10.528013
Autor:
Andrew M. Bell, Andrew J. Todd, Raphaelle Quillet, Kieran A. Boyle, Masahiko Watanabe, Artur Kania, Erika Polgár, Wafa A. A. Alsulaiman, Maria Gutierrez-Mecinas, Allen C. Dickie, R. Brian Roome
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports
Scientific Reports
A recently developed Phox2a::Cre mouse line has been shown to capture anterolateral system (ALS) projection neurons. Here, we used this line to test whether Phox2a-positive cells represent a distinct subpopulation among lamina I ALS neurons. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b2687b38e0d3209d8e690fea3d22ed
https://doaj.org/article/45445ef9894d49f187740e8e7d79332d
https://doaj.org/article/45445ef9894d49f187740e8e7d79332d
Autor:
Han-Shen Tae, Kelly M. Smith, A. Marie Phillips, Kieran A. Boyle, Melody Li, Ian C. Forster, Robert J. Hatch, Robert Richardson, David I. Hughes, Brett A. Graham, Steven Petrou, Christopher A. Reid
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Gabapentin (GBP) is widely used to treat epilepsy and neuropathic pain. There is evidence that GBP can act on hyperpolarization-activated cation (HCN) channel-mediated Ih in brain slice experiments. However, evidence showing that GBP directly modulat
Externí odkaz:
https://doaj.org/article/3f9fcd99967a47b0be0f24a378bc8dff
Autor:
Teodora Trendafilova, Kaustubh Adhikari, Annina B. Schmid, Ryan Patel, Erika Polgár, Kieran A. Boyle, Allen C. Dickie, Andrew M. Bell, Luis Miguel Ramirez-Aristeguieta, Samar Khoury, Aleksandar Ivanov, Mandy Tseng, Hendrik Wildner, Eleanor Ferris, Juan-Camilo Chacón-Duque, Sophie Sokolow, Mohamed A. Saad Boghdady, André Herchuelz, Pierre Faux, Giovanni Poletti, Carla Gallo, Francisco Rothhammer, Gabriel Bedoya, Hanns Ulrich Zeilhofer, Luda Diatchenko, Andrew J. Todd, Anthony H. Dickenson, Andres Ruiz-Linares, David L. Bennett
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793481be9370f7af98657d0ddb6e92ed
https://doi.org/10.2139/ssrn.3933293
https://doi.org/10.2139/ssrn.3933293
Autor:
Christopher V. Dayas, Kelly M. Smith, Kieran A. Boyle, Mark A Gradwell, Alison M. Bell, David Hughes, F. S. Peralta Reyes, Brendan A. Graham, Robert J. Callister, J. Leonardo, Tyler J Browne, A. C. Dickie
Parvalbumin-expressing interneurons (PVINs) in the spinal dorsal horn are found primarily in laminae II inner and III. Inhibitory PVINs (iPVINs) play an important in segregating innocuous tactile input from pain-processing circuits, achieved through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b2778309046e8b36980ac89ac234515
https://doi.org/10.1101/2020.12.23.424233
https://doi.org/10.1101/2020.12.23.424233
Autor:
Kieran A. Boyle, Ernest Palomer, Alasdair J. Gibb, Nuria Martin-Flores, Patricia C. Salinas, Aude Marzo, Thaw Zin Moe, Faye McLeod
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Structural plasticity of synapses correlates with changes in synaptic strength. Dynamic modifications in dendritic spine number and size are crucial for long-term potentiation (LTP), the cellular correlate of learning and memory. Recent studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63bc5270b60eceb8f8e56b359bdb702
https://doi.org/10.3389/fnsyn.2020.575863
https://doi.org/10.3389/fnsyn.2020.575863