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Autor:
Manish Aryal, David Lin, Kiera Regan, Shoucheng Du, Haibin Shi, John J. Alvarado, Tatiana V. Ilina, Amy H. Andreotti, Thomas E. Smithgall
Publikováno v:
Sci Signal
The Nef protein produced by the viruses HIV-1 and SIV drives efficient viral replication partially by inducing constitutive activation of host cell tyrosine kinases, including members of the Src and Tec families. Here, we uncovered the mechanism by w