Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kiera Clayton"'
Autor:
Subha Dahal, Kiera Clayton, Terek Been, Raphaële Fernet-Brochu, Alonso Villasmil Ocando, Ahalya Balachandran, Mikaël Poirier, Rebecca Kaddis Maldonado, Lulzim Shkreta, Kayluz Frias Boligan, Furkan Guvenc, Fariha Rahman, Donald Branch, Brendan Bell, Benoit Chabot, Scott D. Gray-Owen, Leslie J. Parent, Alan Cochrane
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-25 (2022)
Plain Language Summary Identifying cellular factors that regulate HIV-1 RNA processing provides important insights into novel strategies to control this infection. Different members of the SR kinase family have distinct roles in regulating virus expr
Externí odkaz:
https://doaj.org/article/f6c59f5364bf49b0a2fb808840fdf7ed
Autor:
Jun Liu, Wei Zhan, Connie J Kim, Kiera Clayton, Hanqi Zhao, Erika Lee, Jin Chao Cao, Blake Ziegler, Alexander Gregor, Feng Yun Yue, Sanja Huibner, Sonya MacParland, Jordan Schwartz, Hai Han Song, Erika Benko, Gabor Gyenes, Colin Kovacs, Rupert Kaul, Mario Ostrowski
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89236 (2014)
A rare subset of IL-10-producing B cells, named regulatory B cells (Bregs), suppresses adaptive immune responses and inflammation in mice. In this study, we examined the role of IL-10-producing B cells in HIV-1 infection. Compared to uninfected contr
Externí odkaz:
https://doaj.org/article/ad91ac88292b46bca3b3fd8d1b13cb13
Autor:
Ali Sakhdari, Shariq Mujib, Bahareh Vali, Feng Yun Yue, Sonya MacParland, Kiera Clayton, Richard Bradley Jones, Jun Liu, Erika Yue Lee, Erika Benko, Colin Kovacs, Jennifer Gommerman, Rupert Kaul, Mario A Ostrowski
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40146 (2012)
Cytotoxic CD8(+) T cells (CTLs) contain virus infections through the release of granules containing both perforin and granzymes. T cell 'exhaustion' is a hallmark of chronic persistent viral infections including HIV. The inhibitory regulatory molecul
Externí odkaz:
https://doaj.org/article/76d8c9b63d264921a05910338fce7ddb
Publikováno v:
The Journal of Immunology. 198:78.4-78.4
Although CD4+ T cells represent the main target cell for HIV/SIV infection, macrophages also contribute to viral reservoirs. Given CD8+ cytotoxic T lymphocytes (CTL) are essential for controlling viral replication, characterizing how they interact wi
Autor:
Kiera Clayton, Mario Ostrowski
Publikováno v:
Encyclopedia of AIDS ISBN: 9781461496106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77bab31222c00d157e58a8c9a0857930
https://doi.org/10.1007/978-1-4614-9610-6_210-1
https://doi.org/10.1007/978-1-4614-9610-6_210-1
Autor:
Kiera Clayton, Matthew Douglas-Vail, A. Rahman, Karyn Medcalf, Irene Xie, Glen Chew, Ravi Tandon, Marion Lanteri, Philip Norris, Steven Deeks, Lishomwa Ndhlovu, Mario Ostrowski
Publikováno v:
The Journal of Immunology. 194:149.5-149.5
Chronic HIV infection results in a loss of HIV-specific CD8+ T cell effector function, termed “exhaustion”, mediated, in part, by the co-inhibitory receptor T cell immunoglobulin mucin domain-3 (Tim-3). Like many other receptors, a soluble form o
Autor:
Kiera Clayton, Matthew Douglas-Vail, Karyn Medcalf, Glen Chew, Ravi Tandon, Lishomwa Ndhlovu, Mario Ostrowski
Publikováno v:
The Journal of Immunology. 192:74.16-74.16
Chronic Human Immunodeficiency Virus Type-1 (HIV) infection results in a loss of HIV-specific CD8+ T cell effector function, termed “exhaustion”, which is mediated, in-part, by the co-inhibitory receptor T-cell immunoglobulin mucin domain-contain
Autor:
Ravi Tandon, Tsuyoshi Fujita, Glen Chew, Mary Margaret Byron, Toshiro Niki, Mitsuomi Hirashima, Jason Barbour, Mario Ostrowski, Kiera Clayton, Marion Lanteri, Naoto Ishii, Persephone Borrow, Philip Norris, Frederick Hecht, Lishomwa Ndhlovu
Publikováno v:
The Journal of Immunology. 190:118.6-118.6
Despite successes with antiretroviral therapy, HIV infection continues to be a significant health burden with patients remaining at risk of non-AIDS defining events. The earliest immunological responses induced during HIV infection are key events in