Cardiovascular concentration–effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and preclinical studies

Autor: Chotsiri, P, Chan, XHS, Capel, RA, Pike, J, Hanboonkunupakarn, B, Lee, SJ, Hanafiah, M, Win, YN, Cremer, MA, Kiechel, J, Ogutu, B, Taylor, WRJ, Burton, RB, Tarning, J, White, NJ

Publikováno v: British Journal of Clinical Pharmacology. 89:1176-1186

Aims:Amodiaquine is a 4-aminoquinoline used extensively for the treatment and prevention of malaria. Orally administered amodiaquine is largely converted to the active metabolite desethylamodiaquine. Amodiaquine can cause bradycardia, hypotension, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7da681d5370dd617eb9a806bbeb23e
https://doi.org/10.1111/bcp.15569

Safety, efficacy and population pharmacokinetics of fixed-dose combination of artesunate-mefloquine in the treatment of acute uncomplicated Plasmodium falciparum malaria in India

Autor: Valecha, N., Srivastava, B., Dubhashi, N. G., Krishnamoorthy Rao, B. H., Ashwani Kumar, Ghosh, S. K., Singh, J. P. N., Kiechel, J. R., Sharma, B., Jullien, V., Dash, A. P., Taylor, W. R. J., Anvikar, A. R.

Publikováno v: Journal of Vector Borne Diseases, Vol 50, Iss 4, Pp 258-264 (2013)
Scopus-Elsevier

Background & objectives: India has switched over to artemisinin-based combination therapy (ACT) for the treatment of acute uncomplicated Plasmodium falciparum malaria and the ACT used in the national programme is artesunate + sulphadoxine-pyrimethami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1958682008447d9efb7bd9b6e758bda1
http://www.mrcindia.org/journal/issues/504258.pdf

Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data

Autor: Abdulla, S, Adam, I, Adjei, G, Adjuik, M, Alemayehu, B, Allan, R, Arinaitwe, E, Ashley, E, Ba, MS, Barennes, H, Barnes, K, Bassat, Q, Baudin, E, Berens-Riha, N, Bjoerkman, A, Bompart, F, Bonnet, M, Borrmann, S, Bousema, T, Brasseur, P, Bukirwa, H, Checchi, F, Dahal, P, D'Alessandro, U, Desai, M, Dicko, A, Djimde, A, Dorsey, G, Doumbo, O, Drakeley, C, Duparc, S, Eshetu, T, Espie, E, Etard, J, Faiz, A, Falade, C, Fanello, C, Faucher, J, Faye, B, Faye, O, Filler, S, Flegg, J, Fofana, B, Fogg, C, Gadalla, N, Gaye, O, Genton, B, Gething, P, Gil, J, Gonzalez, R, Grandesso, F, Greenhouse, B, Greenwood, B, Grivoyannis, A, Guerin, P, Guthmann, J, Hamed, K, Hamour, S, Hay, S, Hodel, E, Humphreys, G, Hwang, J, Ibrahim, M, Jima, D, Jones, J, Jullien, V, Juma, E, Kachur, P, Kager, P, Kamugisha, E, Kamya, MR, Karema, C, Kayentao, K, Kiechel, J, Kironde, F, Kofoed, P, Kremsner, P, Krishna, S, Lameyre, V, Lell, B, Lima, A, Makanga, M, Malik, E, Marsh, K, Martensson, A, Massougbodji, A, Menan, H, Menard, D, Menendez, C, Mens, P, Meremikwu, M, Moreira, C, Nabasumba, C, Nambozi, M, Ndiaye, J, Ngasala, B, Nikiema, F, Nsanzabana, C, Ntoumi, F, Oguike, M, Ogutu, B, Olliaro, P, Omar, SA, Ouedraogo, J, Owusu-Agyei, S, Penali, L, Pene, M, Peshu, J, Piola, P, Plowe, C, Premji, Z, Price, R, Randrianarivelojosia, M, Rombo, L, Roper, C, Rosenthal, P, Sagara, I, Same-Ekobo, A, Sawa, P, Schallig, H, Schramm, B, Seck, A, Shekalaghe, SA, Sibley, C, Sinou, V, Sirima, S, Som, F, Sow, D, Staedke, S, Stepniewska, K, Sutherland, C, Swarthout, T, Sylla, K, Talisuna, A, Taylor, W, Temu, E, Thwing, J, Tine, R, Tinto, H, Tommasini, S, Toure, O, Ursing, J, Vaillant, M, Valentini, G, Van den Broek, I, Van Vugt, M, Ward, SA, Winstanley, P, Yavo, W, Yeka, A, Zolia, Y, Zongo, I, Based, W

Publikováno v: BMC Medicine
BMC Medicine, BioMed Central, 2015, 13 (212), pp.1-16. ⟨10.1186/s12916-015-0445-x⟩
Abdulla, S, Adam, I, Adjei, G O, Adjuik, M A, Alemayehu, B, Allan, R, Arinaitwe, E, Ashley, E A, Ba, M S, Barennes, H, Barnes, K I, Bassat, Q, Baudin, E, Berens-Riha, N, Bjorkman, A, Bompart, F, Bonnet, M, Borrmann, S, Bousema, T, Brasseur, P, Bukirwa, H, Checchi, F, Dahal, P, D'Alessandro, U, Desai, M, Dicko, A, Djimde, A A, Dorsey, G, Doumbo, O K, Drakeley, C J, Duparc, S, Eshetu, T, Espie, E, Etard, J F, Faiz, A M, Falade, C O, Fanello, C I, Faucher, J F, Faye, B, Faye, O, Filler, S, Flegg, J A, Fofana, B, Fogg, C, Gadalla, N B, Gaye, O, Genton, B, Gething, P W, Gil, J P, Gonzalez, R, Grandesso, F, Greenhouse, B, Greenwood, B, Grivoyannis, A, Guerin, P J, Guthmann, J P, Hamed, K, Hamour, S, Hay, S I, Hodel, E M, Humphreys, G S, Hwang, J, Ibrahim, M L, Jima, D, Jones, J J, Jullien, V, Juma, E, Kachur, P S, Kager, P A, Kamugisha, E, Kamya, M R, Karema, C, Kayentao, K, Kiechel, J R, Kironde, F, Kofoed, P E, Kremsner, P G, Krishna, S, Lameyre, V, Lell, B, Lima, A, Makanga, M, Malik, E M, Marsh, K, Martensson, A, Massougbodji, A, Menan, H, Menard, D, Menendez, C, Mens, P F, Meremikwu, M, Moreira, C, Nabasumba, C, Nambozi, M, Ndiaye, J L, Ngasala, B E, Nikiema, F, Nsanzabana, C, Ntoumi, F & Oguike, M 2015, ' Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria : a literature review and meta-analysis of individual patient data ', B M C Medicine, vol. 13, 212 . https://doi.org/10.1186/s12916-015-0445-x

WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group; International audience; Background: Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong sub-region and poses a major global public health threat.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cccc990c9796c85a37b48c74115c9155
https://pubmed.ncbi.nlm.nih.gov/26429335

A PHASE 4 RANDOMISED STUDY TO ASSESS THE TOLERABILITY OF ARTESUNATE-AMODIAQUINE (ASAQ) AND ARTEMETHER-LUMEFANTRINE (AL) FIXED DOSE COMBINATIONS (FDCS) FOR THE TREATMENT OF UNCOMPLICATED PLASMODIUM FALCIPARUM (PF) MALARIA IN LIBERIA

Autor: Schramm, B, Valeh, P, Baudin, E, Mazinda, C, Smith, R, Pinoges, L, Sundaygar, T, Zolia, Y, Jones, J, Comte, E, Jullien, V, Carn, G, Kiechel, J, Ashley, E, Guerin, P

Publikováno v: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 83(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::27b70e72870c1888b31a8c1f74ade8c5
http://ora.ox.ac.uk/objects/uuid:2e5d55f5-d90b-4f7e-bd8e-469a2dbbd86d

A new pediatric tablet strength of benznidazole for the treatment of chagas disease

Autor: Terlouw, D. J., Alves, F. P., Sosa-Estani, S., Freilij, H., Altcheh, J., Brutus, Laurent, Kiechel, J. R., Ribeiro, I.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______932::6fa6955a78b337fa13b5bbe1c673859e
http://www.documentation.ird.fr/hor/fdi:010049292