Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kidney Precision Medicine Project"'
Autor:
Lutnick, Brendon, Manthey, David, Becker, Jan U, Ginley, Brandon, Moos, Katharina, Zuckerman, Jonathan E, Rodrigues, Luis, Gallan, Alexander J, Barisoni, Laura, Alpers, Charles E, Wang, Xiaoxin X, Myakala, Komuraiah, Jones, Bryce A, Levi, Moshe, Kopp, Jeffrey B, Yoshida, Teruhiko, Zee, Jarcy, Han, Seung Seok, Jain, Sanjay, Rosenberg, Avi Z, Jen, Kuang Yu, Sarder, Pinaki, Kidney Precision Medicine Project
Publikováno v:
Communications medicine, vol 2, iss 1
Background Image-based machine learning tools hold great promise for clinical applications in pathology research. However, the ideal end-users of these computational tools (e.g., pathologists and biological scientists) often lack the programming expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3532ed73d43162764b68b7a7cf7c684e
https://doi.org/10.1038/s43856-022-00138-z
https://doi.org/10.1038/s43856-022-00138-z
Autor:
Hansen, Jens, Sealfon, Rachel, Menon, Rajasree, Eadon, Michael T, Lake, Blue B, Steck, Becky, Anjani, Kavya, Parikh, Samir, Sigdel, Tara K, Zhang, Guanshi, Velickovic, Dusan, Barwinska, Daria, Alexandrov, Theodore, Dobi, Dejan, Rashmi, Priyanka, Otto, Edgar A, Rivera, Miguel, Rose, Michael P, Anderton, Christopher R, Shapiro, John P, Pamreddy, Annapurna, Winfree, Seth, Xiong, Yuguang, He, Yongqun, de Boer, Ian H, Hodgin, Jeffrey B, Barisoni, Laura, Naik, Abhijit S, Sharma, Kumar, Sarwal, Minnie M, Zhang, Kun, Himmelfarb, Jonathan, Rovin, Brad, El-Achkar, Tarek M, Laszik, Zoltan, He, John Cijiang, Dagher, Pierre C, Valerius, M Todd, Jain, Sanjay, Satlin, Lisa M, Troyanskaya, Olga G, Kretzler, Matthias, Iyengar, Ravi, Azeloglu, Evren U, Kidney Precision Medicine Project
Publikováno v:
Science advances, vol 8, iss 23
Kidney Precision Medicine Project (KPMP) is building a spatially specified human kidney tissue atlas in health and disease with single-cell resolution. Here, we describe the construction of an integrated reference map of cells, pathways, and genes us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::47af9eba269707c5ed6ceac065e21301
https://escholarship.org/uc/item/1rg1b3nt
https://escholarship.org/uc/item/1rg1b3nt
Autor:
Rashmi, Priyanka, Sur, Swastika, Sigdel, Tara K, Boada, Patrick, Schroeder, Andrew W, Damm, Izabella, Kretzler, Matthias, Hodgin, Jeff, Hartoularos, George, Jimmie Ye, Chun, Sarwal, Minnie M, Kidney Precision Medicine Project
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol 22, iss 3
Maintenance of systemic homeostasis by kidney requires the coordinated response of diverse cell types. The use of single-cell RNA sequencing (scRNAseq) for patient tissue samples remains fraught with difficulties with cell isolation, purity, and expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::5e73c284b02ebd69ba70ee85a4704b75
https://escholarship.org/uc/item/9sn4x6sk
https://escholarship.org/uc/item/9sn4x6sk
Akademický článek
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Autor:
de Boer, Ian H, Alpers, Charles E, Azeloglu, Evren U, Balis, Ulysses GJ, Barasch, Jonathan M, Barisoni, Laura, Blank, Kristina N, Bomback, Andrew S, Brown, Keith, Dagher, Pierre C, Dighe, Ashveena L, Eadon, Michael T, El-Achkar, Tarek M, Gaut, Joseph P, Hacohen, Nir, He, Yongqun, Hodgin, Jeffrey B, Jain, Sanjay, Kellum, John A, Kiryluk, Krzysztof, Knight, Richard, Laszik, Zoltan G, Lienczewski, Chrysta, Mariani, Laura H, McClelland, Robyn L, Menez, Steven, Moledina, Dennis G, Mooney, Sean D, O'Toole, John F, Palevsky, Paul M, Parikh, Chirag R, Poggio, Emilio D, Rosas, Sylvia E, Rosengart, Matthew R, Sarwal, Minnie M, Schaub, Jennifer A, Sedor, John R, Sharma, Kumar, Steck, Becky, Toto, Robert D, Troyanskaya, Olga G, Tuttle, Katherine R, Vazquez, Miguel A, Waikar, Sushrut S, Williams, Kayleen, Wilson, Francis Perry, Zhang, Kun, Iyengar, Ravi, Kretzler, Matthias, Himmelfarb, Jonathan, Kidney Precision Medicine Project
Publikováno v:
Kidney international, vol 99, iss 3
Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous, and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate a precision-medicine approach to prevention, diagnosis, and treatment. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::991302899070ce130705254930a836bf
https://escholarship.org/uc/item/97q1f55m
https://escholarship.org/uc/item/97q1f55m
Autor:
Tara K. Sigdel, Paul D. Piehowski, Sudeshna Roy, Juliane Liberto, Joshua R. Hansen, Adam C. Swensen, Rui Zhao, Ying Zhu, Priyanka Rashmi, Andrew Schroeder, Izabella Damm, Swastika Sur, Jinghui Luo, Yingbao Yang, Wei-Jun Qian, Minnie M. Sarwal, The Kidney Precision Medicine Project (KPMP) Consortium
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Frontiers in Medicine
Frontiers in Medicine
Molecular assessments at the single cell level can accelerate biological research by providing detailed assessments of cellular organization and tissue heterogeneity in both disease and health. The human kidney has complex multi-cellular states with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881a611cb9ae138aedcc1179e4e966c1
https://www.frontiersin.org/article/10.3389/fmed.2020.00499/full
https://www.frontiersin.org/article/10.3389/fmed.2020.00499/full
Autor:
Melissa A. Haendel, Jennifer A. Schaub, Matthias Kretzler, Frederick Dowd, Sanjay Jain, Sushrut S. Waikar, Laura Barisoni, Christian J. Stoeckert, M. Todd Valerius, Ravi Iyengar, Alexander D. Diehl, Theodore Alexandrov, Edison Ong, Yongqun He, Sean D. Mooney, Dana C. Crawford, Lucy Lu Wang, John F. O’Toole, Ian H. de Boer, Avi Z. Rosenberg, Christopher Y. Park, Chunhua Weng, Christopher J. Mungall, Peter N. Robinson, Jonathan Himmelfarb, Christopher R. Anderton, Becky Steck, Jens Hansen
Publikováno v:
Nat Rev Nephrol
Nature reviews. Nephrology, vol 16, iss 11
Nature reviews. Nephrology, vol 16, iss 11
An important need exists to better understand and stratify kidney disease according to its underlying pathophysiology in order to develop more precise and effective therapeutic agents. National collaborative efforts such as the Kidney Precision Medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792441d58ac585586b4277167c52a5e4
https://pubmed.ncbi.nlm.nih.gov/32939051
https://pubmed.ncbi.nlm.nih.gov/32939051
Akademický článek
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Akademický článek
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