Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kiavash, Movahedi"'
Autor:
Sahana Srinivasan, Daliya Kancheva, Sofie De Ren, Takashi Saito, Maude Jans, Fleur Boone, Charysse Vandendriessche, Ine Paesmans, Hervé Maurin, Roosmarijn E. Vandenbroucke, Esther Hoste, Sofie Voet, Isabelle Scheyltjens, Benjamin Pavie, Saskia Lippens, Marius Schwabenland, Marco Prinz, Takaomi Saido, Astrid Bottelbergs, Kiavash Movahedi, Mohamed Lamkanfi, Geert van Loo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAlzheimer’s disease (AD) is the most common neurodegenerative disorder affecting memory and cognition. The disease is accompanied by an abnormal deposition of ß-amyloid plaques in the brain that contributes to neurodegeneration and is kn
Externí odkaz:
https://doaj.org/article/9176fde1a9644a96960b77fefeca6640
Autor:
Lien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Lieve Moons, Kiavash Movahedi
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract The multifaceted nature of neuroinflammation is highlighted by its ability to both aggravate and promote neuronal health. While in mammals retinal ganglion cells (RGCs) are unable to regenerate following injury, acute inflammation can induce
Externí odkaz:
https://doaj.org/article/c5d393174a4c4577ad8089b2e38b0f55
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The liver is a vital metabolic organ that also performs important immune-regulatory functions. In the context of infections, the liver represents a target site for various pathogens, while also having an outstanding capacity to filter the blood from
Externí odkaz:
https://doaj.org/article/e6f8df39d33f46b4b0ff6328db380988
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Despite relentless efforts to improve outcome, the prognosis of glioblastoma (GBM) remains poor. Standard therapy at first diagnosis consists of maximal safe surgical resection followed by radiochemotherapy, but treatment options at recurrence are sc
Externí odkaz:
https://doaj.org/article/381dd0dc6310466496ade546db962b92
Autor:
Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, Jeroen Aerts, Niels Vandamme, Ruth Seurinck, Kevin Verstaen, Gert Hulselmans, Silvie Van den Hoecke, Isabelle Scheyltjens, Kiavash Movahedi, Hans Wils, Joke Reumers, Jeroen Van Houdt, Stein Aerts, Yvan Saeys
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background Multiplexing of samples in single-cell RNA-seq studies allows a significant reduction of the experimental costs, straightforward identification of doublets, increased cell throughput, and reduction of sample-specific batch effects
Externí odkaz:
https://doaj.org/article/70cb4b7c707e493b8f024717bdd552fa
Autor:
James Boot, Gabriel Rosser, Dailya Kancheva, Claire Vinel, Yau Mun Lim, Nicola Pomella, Xinyu Zhang, Loredana Guglielmi, Denise Sheer, Michael Barnes, Sebastian Brandner, Sven Nelander, Kiavash Movahedi, Silvia Marino
Publikováno v:
eLife, Vol 11 (2022)
We describe a subset of glioblastoma, the most prevalent malignant adult brain tumour, harbouring a bias towards hypomethylation at defined differentially methylated regions. This epigenetic signature correlates with an enrichment for an astrocytic g
Externí odkaz:
https://doaj.org/article/da3de84103274f4e822d1df1abc6378c
Autor:
Chritica Lodder, Isabelle Scheyltjens, Ilie Cosmin Stancu, Pablo Botella Lucena, Manuel Gutiérrez de Ravé, Sarah Vanherle, Tim Vanmierlo, Niels Cremers, Hannah Vanrusselt, Bert Brône, Bernard Hanseeuw, Jean-Noël Octave, Astrid Bottelbergs, Kiavash Movahedi, Ilse Dewachter
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Alzheimer's disease (AD) is characterized by a sequential progression of amyloid plaques (A), neurofibrillary tangles (T) and neurodegeneration (N), constituting ATN pathology. While microglia are considered key contributors to AD pathogenes
Externí odkaz:
https://doaj.org/article/852fe2a6f7d24a1d8306a8d889edd584
Autor:
Karen De Vlaminck, Ema Romão, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A. Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi, Geert Raes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Glioblastoma (GBM) is the most common malignant primary brain tumor. Glioblastomas contain a large non-cancerous stromal compartment including various populations of tumor-associated macrophages and other myeloid cells, of which the presence was docu
Externí odkaz:
https://doaj.org/article/22816153b4a84f9e978050703b2fef79
Autor:
Evangelia Bolli, Maximilian Scherger, Sana M. Arnouk, Ana Rita Pombo Antunes, David Straßburger, Moritz Urschbach, Judith Stickdorn, Karen De Vlaminck, Kiavash Movahedi, Hans Joachim Räder, Sophie Hernot, Pol Besenius, Jo A. Van Ginderachter, Lutz Nuhn
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies. To repolarize their phenotype into a
Externí odkaz:
https://doaj.org/article/cac8fa4c5d6f47508fc134a4bcd703ea
Autor:
Bart Neyns, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Modulation and depletion strategies of regulatory T cells (Tregs) constitute valid approaches in antitumor immunotherapy but suffer from severe adverse effects due to their lack of selectivity for the tumor-infiltrating (ti-)Treg populatio
Externí odkaz:
https://doaj.org/article/f3b73327b159432399d5c58c01682dd6