Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kiara Held"'
Autor:
Amelia R. Silva-Rohwer, Kiara Held, Janelle Sagawa, Nicolas L. Fernandez, Christopher M. Waters, Viveka Vadyvaloo
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Plague-causing Yersinia pestis is transmitted through regurgitation when it forms a biofilm-mediated blockage in the foregut of its flea vector. This biofilm is composed of an extracellular polysaccharide substance (EPS) produced when cyclic
Externí odkaz:
https://doaj.org/article/8b298241fa20412c80f6b7c1df85c1a9
Autor:
Erin P. Smith, Alexis Cotto-Rosario, Elizabeth Borghesan, Kiara Held, Cheryl N. Miller, Jean Celli
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Intracellular bacterial pathogens remodel cellular functions during their infectious cycle via the coordinated actions of effector molecules delivered through dedicated secretion systems. While the function of many individual effectors is kn
Externí odkaz:
https://doaj.org/article/f7dfe2eccd2248279ea9482b3b7e79ea
Publikováno v:
mBio, Vol 3, Iss 2 (2012)
ABSTRACT To help define the biological functions of nonessential genes of Francisella novicida, we measured the growth of arrayed members of a comprehensive transposon mutant library under a variety of nutrition and stress conditions. Mutant phenotyp
Externí odkaz:
https://doaj.org/article/ccf55f3555474e7d86cf56ddf7f620ea
Publikováno v:
Journal of Bacteriology.
Mutations enhancing c-di-GMP biosynthesis drove the evolution of Y. pestis to flea-borne transmissibility. c-di-GMP-dependent biofilm-mediated blockage of the flea foregut enables regurgitative transmission of Y. pestis by fleabite. The Y. pestis dig
Autor:
Nicolas L. Fernandez, Amelia R Silva-Rohwer, Janelle Sagawa, Viveka Vadyvaloo, Christopher M. Waters, Kiara Held
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
Plague-causing Yersinia pestis is transmitted through regurgitation when it forms a biofilm-mediated blockage in the foregut of its flea vector. This biofilm is composed of an extracellular polysaccharide substance (EPS) produced when cyclic-di-GMP (
Autor:
Cheryl N. Miller, Erin P. Smith, Elizabeth Borghesan, Jean Celli, Alexis Cotto-Rosario, Kiara Held
Publikováno v:
mBio, Vol 11, Iss 2, p e03350-19 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio, Vol 11, Iss 2 (2020)
Intracellular bacterial pathogens remodel cellular functions during their infectious cycle via the coordinated actions of effector molecules delivered through dedicated secretion systems. While the function of many individual effectors is known, how
Slow-growing bacteria are insensitive to killing by antibiotics, a trait known as antibiotic tolerance. In this study, we characterized the genetic basis of an unusually robust β-lactam (meropenem) tolerance seen in Burkholderia species. We identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2392117ea67fd0ff5e66ac5d5d9d860
https://europepmc.org/articles/PMC5913950/
https://europepmc.org/articles/PMC5913950/
Autor:
Kiara Held, Roxanne Erolin, Larry A. Gallagher, Eli J. Weiss, Mitch Brittnacher, Beth Ramage, Colin Manoil, Joe Gasper
Publikováno v:
Journal of bacteriology. 199(20)
Klebsiella pneumoniae and other carbapenem-resistant members of the family Enterobacteriaceae are a major cause of hospital-acquired infections, yet the basis of their success as nosocomial pathogens is poorly understood. To help provide a foundation
Publikováno v:
Applied and Environmental Microbiology. 73:7622-7628
Photorhabdus luminescens is a gram-negative insect pathogen that enters the hemocoel of infected hosts and produces a number of secreted proteins that promote colonization and subsequent death of the insect. In initial studies to determine the exact
Autor:
Kiara Held, Inessa Gendlina, Catalin E. Doneanu, Carleen M. Collins, Sara Schesser Bartra, David R. Goodlett, Byron Gallis, Gregory V. Plano
Publikováno v:
Molecular Microbiology. 64:1214-1227
Plague, or the Black Death, is a zoonotic disease that is spread from mammal to mammal by fleas. This mode of transmission demands that the causative agent of this disease, Yersinia pestis, is able to survive and multiply in both mammals and insects.