Výsledky vyhledávání - "Kiana M, Schulze"

Akademický článek

Pulmonary hypertension alters blood flow distribution and impairs the hyperemic response in the rat diaphragm

Autor: Kiana M. Schulze, Andrew G. Horn, Ramona E. Weber, Bradley J. Behnke, David C. Poole, Timothy I. Musch

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling, respiratory muscle and cardiac impairments, and exercise intolerance. Specifically, impaired gas exchange increases work of the diaphragm; however, compromised contractile

Externí odkaz: https://doaj.org/article/a42085f5bca846f98c4a8302d5e5253f

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Akademický článek

Associations of Cerebrovascular Regulation and Arterial Stiffness With Cerebral Small Vessel Disease: A Systematic Review and Meta‐Analysis

Autor: Britton C. Scheuermann, Shannon K. Parr, Kiana M. Schulze, Olivia N. Kunkel, Vanessa‐Rose G. Turpin, Jia Liang, Carl J. Ade

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 23 (2023)

Background Cerebral small vessel disease (cSVD) is a major contributing factor to ischemic stroke and dementia. However, the vascular pathologies of cSVD remain inconclusive. The aim of this systematic review and meta‐analysis was to characterize t

Externí odkaz: https://doaj.org/article/459f6046c61244f0b178f672a7e82834

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Supplemental oxygen administration during mechanical ventilation reduces diaphragm blood flow and oxygen delivery

Autor: Andrew G. Horn, Olivia N. Kunkel, Kiana M. Schulze, Dryden R. Baumfalk, Ramona E. Weber, David C. Poole, Bradley J. Behnke

Publikováno v: J Appl Physiol (1985)

During mechanical ventilation (MV), supplemental oxygen (O(2)) is commonly administered to critically ill patients to combat hypoxemia. Previous studies demonstrate that hyperoxia exacerbates MV-induced diaphragm oxidative stress and contractile dysf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581a77da7046be4154c0c2dfca664b1b
https://pubmed.ncbi.nlm.nih.gov/35323060

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The effects of pulmonary hypertension on skeletal muscle oxygen pressures in contracting rat spinotrapezius muscle

Autor: David C. Poole, Ramona E. Weber, Trenton D. Colburn, Carl J. Ade, Andrew G. Horn, Kiana M. Schulze, Wei-Wen Hsu, Timothy I. Musch

Publikováno v: Exp Physiol

NEW FINDINGS What is the central question of this study? Does impairment in the dynamics of O2 transport in skeletal muscle during a series of contractions constitute a potential mechanism underlying reduced exercise capacity in pulmonary hypertensio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d09b76f941691871bff3fea371318a5
https://doi.org/10.1113/ep089631

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Vascular ATP‐sensitive K+channels support maximal aerobic capacity and critical speed via convective and diffusive O2transport

Autor: Kiana M. Schulze, K. Sue Hageman, David C. Poole, Jacob T. Caldwell, Ramona E. Weber, Carl J. Ade, Brad J. Behnke, Trenton D. Colburn, Timothy I. Musch

Publikováno v: The Journal of Physiology. 598:4843-4858

KEY POINTS: Oral sulphonylureas, widely prescribed in diabetes, inhibit pancreatic ATP-sensitive K+ (KATP ) channels to increase insulin release. However, KATP channels are also located within vascular (endothelium and smooth muscle) and muscle (card

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::756ab6d1de9e47383e407c16a8591af9
https://doi.org/10.1113/jp280232

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Capillary hemodynamics and contracting skeletal muscle oxygen pressures in male rats with heart failure: Impact of soluble guanylyl cyclase activator

Autor: Ramona E. Weber, Kiana M. Schulze, Trenton D. Colburn, Andrew G. Horn, K. Sue Hageman, Carl J. Ade, Stephanie E. Hall, Peter Sandner, Timothy I. Musch, David C. Poole

Publikováno v: Nitric Oxide

In heart failure with reduced ejection fraction (HFrEF), nitric oxide-soluble guanylyl cyclase (sGC) pathway dysfunction impairs skeletal muscle arteriolar vasodilation and thus capillary hemodynamics, contributing to impaired oxygen uptake [Formula:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a665c159905224d72393e466f61a0979
https://europepmc.org/articles/PMC9469501/

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Effects of pulmonary hypertension on microcirculatory hemodynamics in rat skeletal muscle

Autor: Kiana M. Schulze, Ramona E. Weber, Andrew G. Horn, Trenton D. Colburn, Carl J. Ade, David C. Poole, Timothy I. Musch

Publikováno v: Microvasc Res

Pulmonary hypertension (PH) has previously been characterized as a disease of the pulmonary vasculature that subsequently results in myocardial dysfunction. Heart failure compromises skeletal muscle microvascular function, which contributes to exerci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6405b074759484487cb31e19e8ea104e
https://pubmed.ncbi.nlm.nih.gov/35104507

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