Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kia N. Zellars"'
Autor:
Olga H. Toro-Salazar, Ji Hyun Lee, Kia N. Zellars, Paige E. Perreault, Kathryn C. Mason, Zhu Wang, Kan N. Hor, Eileen Gillan, Caroline J. Zeiss, Daniel M. Gatti, Brooke T. Davey, Shelby Kutty, Bruce T. Liang, Francis G. Spinale
Publikováno v:
Cardio-Oncology, Vol 4, Iss 1, Pp 1-11 (2018)
Abstract Background Anthracycline induced cardiomyopathy is a major cause of mortality and morbidity among pediatric cancer survivors. It has been postulated that oxidative stress induction and inflammation may play a role in the pathogenesis of this
Externí odkaz:
https://doaj.org/article/81eee6c0ac974fc38f9cb55f49d53ef9
Autor:
Mitchel R. Stacy, Ben A. Lin, Stephanie L. Thorn, David C. Lobb, Mark W. Maxfield, Craig Novack, Kia N. Zellars, Lisa Freeburg, Joseph G. Akar, Albert J. Sinusas, Francis G. Spinale
Publikováno v:
Heart Rhythm
BACKGROUND: Left ventricular (LV) remodeling following a myocardial infarction (MI) is associated with new onset atrial fibrillation (AF). LV remodeling post-MI is characterized by regional changes in matrix metalloproteinases (MMPs) and tissue inhib
Autor:
Yimu Lai, Heather Doviak, Valerie K. Laney, Lisa A. Freeburg, Kia N. Zellars, Laura B. Snyder, Francis G. Spinale, Lydia E. Matesic, Amber Moore
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H976-H984
Heart failure with a preserved left ventricular (LV) ejection fraction (HFpEF) often arises from a prolonged LV pressure overload (LVPO) and is accompanied by abnormal extracellular matrix (ECM) accumulation. It is now recognized that the ECM is a dy
Autor:
Kia N. Zellars, Eva Romito, Heather Doviak, Tae-Weon Lee, Gregory L. Brower, Parker D. Freels, Stephen W. Smith, David C Lobb, James A Shuman, Lisa A. Freeburg, Francis G. Spinale, Aarif Y. Khakoo, Jason W. O’Neill
Publikováno v:
J Pharmacol Exp Ther
Infarct expansion can occur after myocardial infarction (MI), which leads to adverse left ventricular (LV) remodeling and failure. An imbalance between matrix metalloproteinase (MMP) induction and tissue inhibitors of MMPs (TIMPs) can accelerate this
Autor:
Laura B, Snyder, Yimu, Lai, Heather, Doviak, Lisa A, Freeburg, Valerie K, Laney, Amber, Moore, Kia N, Zellars, Lydia E, Matesic, Francis G, Spinale
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 321(5)
Heart failure with a preserved left ventricular (LV) ejection fraction (HFpEF) often arises from a prolonged LV pressure overload (LVPO) and accompanied by abnormal extracellular matrix (ECM) accumulation. The E
Autor:
Edie C. Goldsmith, Amber Moore, Kia N. Zellars, Lisa A. Freeburg, Laura Snyder, Paige E. Perreault, Lauren-Ashley Michelle Duncan, Lydia E. Matesic, Francis G. Spinale
Publikováno v:
Am J Physiol Heart Circ Physiol
Ubiquitylation is a key event that regulates protein turnover, and induction of the ubiquitin ligase E3 WWP1 has been associated with age. Left ventricular hypertrophy (LVH) commonly occurs as a function of age and can cause heart failure (HF) with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22fe00ed8d17b7a3f10fb5b0e3a7153
https://europepmc.org/articles/PMC7717125/
https://europepmc.org/articles/PMC7717125/
Autor:
Shayne C. Barlow, TaeWeon Lee, Heather Doviak, Ran Klein, Julia Jacobs, Robert A. deKemp, Kia N. Zellars, Albert J. Sinusas, Jennifer M. Renaud, Stephanie Thorn, Mitchel R. Stacy, Attila Feher, Aarif Y. Khakoo, Francis G. Spinale
Publikováno v:
Circulation: Cardiovascular Imaging. 12
Background: The induction of matrix metalloproteinases (MMPs) and reduction in tissue inhibitors of MMPs (TIMPs) plays a role in ischemia/reperfusion (I/R) injury post-myocardial infarction (MI) and subsequent left ventricular remodeling. We develope
Autor:
Shelby Kutty, Ji Hyun Lee, Eileen Gillan, Olga H. Toro-Salazar, Kia N. Zellars, Zhu Wang, Caroline J. Zeiss, Kathryn C. Mason, Brooke Davey, Daniel M. Gatti, Bruce T. Liang, Paige E Perreault, Kan N Hor, Francis G. Spinale
Publikováno v:
Cardio-Oncology, Vol 4, Iss 1, Pp 1-11 (2018)
Cardio-oncology (London, England)
Cardio-oncology (London, England)
Background Anthracycline induced cardiomyopathy is a major cause of mortality and morbidity among pediatric cancer survivors. It has been postulated that oxidative stress induction and inflammation may play a role in the pathogenesis of this process.
Autor:
Francis G. Spinale, Kia N. Zellars, Mark A. Sarzynski, Kurt G. Barringhaus, Jacob L. Barber, Claude Bouchard
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
The purpose of the present study was to examine the effects of regular exercise on the abundance of targeted circulating microRNAs (miRNAs). The present analysis examined 20 previously sedentary adults from the HERITAGE Family Study who completed 20
Autor:
Kelsie E. Oatmen, Kan Hor, Francis G. Spinale, Kia N. Zellars, Olga H. Toro-Salazar, Caroline J. Zeiss, Kathryn C. Mason, Eileen Gillan, Daniel M. Gatti, Kristine Hauser
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 315(5)
Anthracycline chemotherapy (AC) is associated with decline in left ventricular ejection fraction (LVEF), yet the mechanisms remain unclear. Although changes in microRNAs (miRs) have been identified in adult cardiovascular disease, miR profiles in ped