Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Ki-jun Yoon"'
Autor:
Byung Su Ko, Myeong Hoon Han, Min Jee Kwon, Dong Gon Cha, Yuri Ji, Eun Seo Park, Min Jae Jeon, Somi Kim, Kyeongho Lee, Yoon Ha Choi, Jusung Lee, Monica Torras-Llort, Ki-Jun Yoon, Hyosang Lee, Jong Kyoung Kim, Sung Bae Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 422-440 (2024)
Abstract Accumulating evidence hints heterochromatin anchoring to the inner nuclear membrane as an upstream regulatory process of gene expression. Given that the formation of neural progenitor cell lineages and the subsequent maintenance of postmitot
Externí odkaz:
https://doaj.org/article/1ec26a52f76942f19aa7aa5402f7c822
Autor:
Mi-Yeon Kim, Mi Jeong Kim, Changyeob Lee, Juwon Lee, Sang Seong Kim, Sungho Hong, Hyoung Tae Kim, Jinsoo Seo, Ki-Jun Yoon, Sungho Han
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 10, Pp 2177-2189 (2023)
Abstract Enhancing adult neurogenesis in the brain has been suggested as a potential therapeutic strategy for AD. We developed a screening platform, ATRIVIEW®, for molecules that activate neuronal differentiation of adult mouse NSCs. The most potent
Externí odkaz:
https://doaj.org/article/ce100d8f20254b649a18dca13e539dfe
Autor:
Sung-Min Lee, Bonsang Koo, Clément Carré, André Fischer, Chuan He, Ajeet Kumar, Kathy Liu, Kate D. Meyer, Guo-li Ming, Junmin Peng, Jean-Yves Roignant, Erik Storkebaum, Shuying Sun, Davide De Pietri Tonelli, Yinsheng Wang, Yi-Lan Weng, Luigi Pulvirenti, Yanhong Shi, Ki-Jun Yoon, Hongjun Song
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Increasing evidence reinforces the essential function of RNA modifications in development and diseases, especially in the nervous system. RNA modifications impact various processes in the brain, including neurodevelopment, neurogenesis, neuroplastici
Externí odkaz:
https://doaj.org/article/b324500bfd034a9b89490eedec6f532c
Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Autor:
Surjeet Mastwal, Xinjian Li, Rianne Stowell, Matthew Manion, Wenyu Zhang, Nam-Shik Kim, Ki-Jun Yoon, Hongjun Song, Guo-Li Ming, Kuan Hong Wang
Publikováno v:
eLife, Vol 12 (2023)
Dopamine system dysfunction is implicated in adolescent-onset neuropsychiatric disorders. Although psychosis symptoms can be alleviated by antipsychotics, cognitive symptoms remain unresponsive and novel paradigms investigating the circuit substrates
Externí odkaz:
https://doaj.org/article/b7a4f6c7002442f99a80d102ea65c327
Autor:
Nam-Shik Kim, Zhexing Wen, Jing Liu, Ying Zhou, Ziyuan Guo, Chongchong Xu, Yu-Ting Lin, Ki-Jun Yoon, Junhyun Park, Michelle Cho, Minji Kim, Xinyuan Wang, Huimei Yu, Srilatha Salamuru, Kimberly M. Christian, Kuei-sen Hsu, Menghang Xia, Weidong Li, Christopher A. Ross, Russell L. Margolis, Xin-Yun Lu, Hongjun Song, Guo-li Ming
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Previous work has shown in iPSC derived neurons that synaptic impairments are associated with a 4bp DISC1 deletion. Here the authors demonstrate a role for the PDE4 signalling pathway in these synaptic impairments.
Externí odkaz:
https://doaj.org/article/a1c93081300b4869a2a2b16a518720f6
Autor:
Guang Song, Emily M. Lee, Jianbo Pan, Miao Xu, Hee-Sool Rho, Yichen Cheng, Nadia Whitt, Shu Yang, Jennifer Kouznetsova, Carleen Klumpp-Thomas, Samuel G. Michael, Cedric Moore, Ki-Jun Yoon, Kimberly M. Christian, Anton Simeonov, Wenwei Huang, Menghang Xia, Ruili Huang, Madhu Lal-Nag, Hengli Tang, Wei Zheng, Jiang Qian, Hongjun Song, Guo-li Ming, Heng Zhu
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 4, Pp 808-809 (2022)
Externí odkaz:
https://doaj.org/article/3d5fe2b25f014bd9a48ec957e2e5487d
Autor:
Jongbo Lee, Jumin Park, Ji-Hyung Kim, Giwook Lee, Tae-Eun Park, Ki-Jun Yoon, Yoon Ki Kim, Chunghun Lim
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3001002 (2020)
Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). Here, we identify a neuroprotective pathway of like-Sm pro
Externí odkaz:
https://doaj.org/article/a21a49d0eb1a425eb4740a4728b73d03
Autor:
Nam-Shik Kim, Zhexing Wen, Jing Liu, Ying Zhou, Ziyuan Guo, Chongchong Xu, Yu-Ting Lin, Ki-Jun Yoon, Junhyun Park, Michelle Cho, Minji Kim, Xinyuan Wang, Huimei Yu, Srilatha Sakamuru, Kimberly M. Christian, Kuei-sen Hsu, Menghang Xia, Weidong Li, Christopher A. Ross, Russell L. Margolis, Xin-Yun Lu, Hongjun Song, Guo-li Ming
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
https://doi.org/10.1038/s41467-021-23263-0
Externí odkaz:
https://doaj.org/article/d5fbb710385541b4bb123850e7c40ecb
Publikováno v:
Viruses, Vol 11, Iss 2, p 124 (2019)
Pathologies induced by viral infections have undergone extensive study, with traditional model systems such as two-dimensional (2D) cell cultures and in vivo mouse models contributing greatly to our understanding of host-virus interactions. However,
Externí odkaz:
https://doaj.org/article/dcd9122e099148a5a2079e183f5d23ce
Autor:
Bon-Kyoung Koo, Mi-Jeong Yoon, Ki-Jun Yoon, Sun-Kyoung Im, Yoon-Young Kim, Cheol-Hee Kim, Pann-Ghill Suh, Yuh Nung Jan, Young-Yun Kong
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1221 (2007)
The Notch signaling pathway is an evolutionarily conserved intercellular signaling module essential for cell fate specification that requires endocytosis of Notch ligands. Structurally distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (M
Externí odkaz:
https://doaj.org/article/aab5ba7cb82842a09f473f2c2fab4a09