Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ki-Yeun Park"'
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2025 (2024)
Objective: Chondrocyte apoptosis has been considered a crucial mechanism that is responsible for cartilage destruction in osteoarthritis (OA). The mechanism of interleukin-37 (IL-37) on chondrocyte apoptosis has not been clearly determined in the pat
Externí odkaz:
https://doaj.org/article/51b1f3d5af6d45179ae2fbd3d745bf88
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 883 (2024)
Objective: The pleiotropic effect of hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) is responsible for potent defense against inflammatory response. This study evaluated the inhibitory effects of HMG-CoA reductase inhibi
Externí odkaz:
https://doaj.org/article/1f0ab0d75a05463c937e6337b9491147
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Objective. Activation of toll-like receptor 9 (TLR9) has been proposed to play an inhibitory role in RANKL-induced osteoclastogenesis. A20 deubiquitinase has been found to be related to bone loss. This study investigated the role of CpG oligodeoxynuc
Externí odkaz:
https://doaj.org/article/adc23f6ce2f44c308355a7d6259d1064
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 522 (2023)
Peroxisome proliferator-activated receptor γ (PPAR-γ) is thought to negatively regulate NLRP3 inflammasome activation. The aim of this study was to identify the inhibitory effect of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibito
Externí odkaz:
https://doaj.org/article/aac87fdacc964f2785630d96f7f04e2f
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 446 (2023)
Histone deacetylase (HDAC) has been found to play a crucial role in the regulation of osteoclast differentiation and formation. This study was designed to identify the effect of the HDAC6 inhibitor CKD-WID on the receptor for the activation of nuclea
Externí odkaz:
https://doaj.org/article/1f6945d0e17848909138e44fe99a3d2f
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 649 (2023)
The aim of this study was to evaluate the expression of chemokine receptor CXCR4 and its ligand CXCL12 in patients with gout and uric acid-induced inflammation. A total of 40 patients with intercritical gout and 27 controls were consecutively enrolle
Externí odkaz:
https://doaj.org/article/457dc326a91746d0bc01b6e97e550409
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
The aim of this study was to clarify the role of monosodium urate (MSU) crystals in receptor activator of nuclear factor kB ligand- (RANKL-) RANK-induced osteoclast formation. RAW 264.7 murine macrophage cells were incubated with MSU crystals or RANK
Externí odkaz:
https://doaj.org/article/21974cf599c74c3f947f8c20244ddfd7
Publikováno v:
Inflammation. 43(6)
The NLR family pyrin domain-containing 3 (NLRP3) inflammasome is a cytoplasmic multimolecular complex that generates interleukin (IL)-1β and is considered a main pathogenic mechanism for uric acid-induced inflammation. Whether toll-like receptor 9 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f00e97da9877d5b9affd4db3bee18a
https://pubmed.ncbi.nlm.nih.gov/32700178
https://pubmed.ncbi.nlm.nih.gov/32700178
Publikováno v:
Biochemical and biophysical research communications. 517(2)
Objective Artemisinin is a potent anti-malarial agent that plays a potent role in regulating inflammatory disorders. NEK7 is a major interacting partner with NLRP3 in NLRP3 inflammasome. The aim of this study was to clarify the anti-inflammatory effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96172f766f1939c751bd99c9a1d992f
https://pubmed.ncbi.nlm.nih.gov/31358323
https://pubmed.ncbi.nlm.nih.gov/31358323
Publikováno v:
Yonsei Medical Journal; Nov2021, Vol. 62 Issue 11, p1023-1031, 9p