Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Ki-Sun Kwon"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2024)
Muscle aging is a complex physiological process that leads to the progressive decline in muscle mass and function, contributing to debilitating conditions in the elderly such as sarcopenia. In recent years, non-coding RNAs (ncRNAs) have been increasi
Externí odkaz:
https://doaj.org/article/79384f4131bc465dbb22cf3d17089801
Autor:
Young Hoon Son, Whoan Jeang Kim, Yeo Jin Shin, Seung-Min Lee, Bora Lee, Kwang-Pyo Lee, Seung Hoon Lee, Kap Jung Kim, Ki-Sun Kwon
Publikováno v:
Experimental Gerontology, Vol 181, Iss , Pp 112273- (2023)
Background: Low back pain is a general phenomenon of aging, and surgery is an unavoidable choice to relieve severe back pain. The discarded surgical site during surgery is of high value for muscle and muscle-related research. This study investigated
Externí odkaz:
https://doaj.org/article/fe54b10c6bf44d5697d0f4c9fa3c16ee
Autor:
Jin-Hyuck Jeong, Jun-Seok Han, Youngae Jung, Seung-Min Lee, So-Hyun Park, Mooncheol Park, Min-Gi Shin, Nami Kim, Mi Sun Kang, Seokho Kim, Kwang-Pyo Lee, Ki-Sun Kwon, Chun-A. Kim, Yong Ryoul Yang, Geum-Sook Hwang, Eun-Soo Kwon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Although diet modulates aging, little is known about whether and how nutrient regulates longevity. Here, the authors show that glucose-restricted diets prolong longevity through series of conserved factors, such as neuronal AMPK, neuropeptide, AdipoR
Externí odkaz:
https://doaj.org/article/9d96c287f7ab4e7690ab27d6f5c60c71
Autor:
Bora Lee, Seon Kyu Kim, Yeo Jin Shin, Young Hoon Son, Jae Won Yang, Seung-Min Lee, Yong Ryul Yang, Kwang-Pyo Lee, Ki-Sun Kwon
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Skeletal muscle communicates with other organs via myokines, which are secreted by muscle during exercise and exert various effects. Despite much investigation of the exercise, the underlying molecular mechanisms are still not fully understo
Externí odkaz:
https://doaj.org/article/211f50283c024b82ae435b1f85bd26fc
Autor:
Jong Hyeon Yoon, Ki-Sun Kwon
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 3, Pp 478-490 (2021)
Sarcopenia is a disease characterized by age-related decline of skeletal muscle mass and function. The molecular mechanisms of the pathophysiology of sarcopenia form a complex network due to the involvement of multiple interconnected signaling pathwa
Externí odkaz:
https://doaj.org/article/cb73ee53d1634153b37cb5be29cdae6c
Publikováno v:
Annals of Geriatric Medicine and Research, Vol 24, Iss 4, Pp 297-304 (2020)
Background Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. Methods Wild-type and Sesn2 knockout (KO) mice of t
Externí odkaz:
https://doaj.org/article/07b45251ed8e4b5bb8b08789ff54a68a
Autor:
Seung-Min Lee, Seol Hee Lee, Youngae Jung, Younglang Lee, Jong Hyun Yoon, Jeong Yi Choi, Chae Young Hwang, Young Hoon Son, Sung Sup Park, Geum-Sook Hwang, Kwang-Pyo Lee, Ki-Sun Kwon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Ageing leads to a loss of muscle mass and strength, called sarcopenia. Here, the authors show that fatty acid binding protein 3 (FABP3), a lipid chaperone, drives age-dependent lipidome remodeling in skeletal muscle and deteriorates muscle mass and c
Externí odkaz:
https://doaj.org/article/fd99792e3593409b8c42a763dceb5467
Autor:
Yeo Jin Shin, Eun‐Soo Kwon, Seung‐Min Lee, Seon‐Kyu Kim, Kyung‐Won Min, Jae‐Young Lim, Bora Lee, Jae Sook Kang, Ju Yeon Kwak, Young Hoon Son, Jeong Yi Choi, Yong Ryul Yang, Seokho Kim, Yeon‐Soo Kim, Hak C. Jang, Yousin Suh, Je‐Hyun Yoon, Kwang‐Pyo Lee, Ki‐Sun Kwon
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1336-1350 (2020)
Abstract Background The microRNAs (miRNAs) down‐regulated in aged mouse skeletal muscle were mainly clustered within the delta‐like homologue 1 and the type III iodothyronine deiodinase (Dlk1‐Dio3) genomic region. Although clustered miRNAs are
Externí odkaz:
https://doaj.org/article/c8b596c5b6a5455eb5388b7550dc5499
Autor:
Ju Yeon Kwak, Ki-Sun Kwon
Publikováno v:
Annals of Geriatric Medicine and Research, Vol 23, Iss 3, Pp 98-104 (2019)
Sarcopenia, the loss of skeletal muscle mass and function with age, was first recognized as a disease in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) (M62.84) and has recently attracted attention as
Externí odkaz:
https://doaj.org/article/cc0d489610b646509195b3066d06b221
Autor:
Yong Ryoul Yang, Ki-Sun Kwon
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity ma
Externí odkaz:
https://doaj.org/article/e57186330cbc4ad88a71e91883e05884