Time-dynamic pulse modulation of spinal cord stimulation reduces mechanical hypersensitivity and spontaneous pain in rats

Autor: Muhammad M. Edhi, Lonne Heijmans, Kevin N. Vanent, Kiernan Bloye, Amanda Baanante, Ki-Soo Jeong, Jason Leung, Changfang Zhu, Rosana Esteller, Carl Y. Saab

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

Abstract Enhancing the efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and dependence on opioids. Present SCS therapies are characterized by the delivery of constant stimulation in the form of trains of ton

Externí odkaz: https://doaj.org/article/13407e805180457ca6392ef3cb28ac16

Time-dynamic pulse modulation of spinal cord stimulation reduces mechanical hypersensitivity and spontaneous pain in rats

Autor: Carl Y. Saab, Jason W. Leung, Muhammad M. Edhi, Kiernan Bloye, Amanda Baanante, Rosana Esteller, Ki-Soo Jeong, Kevin N. Vanent, Changfang Zhu, Lonne Heijmans

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1):20358. Nature Publishing Group
Scientific Reports

Enhancing the efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and dependence on opioids. Present SCS therapies are characterized by the delivery of constant stimulation in the form of trains of tonic pulses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d4580021a326aea31690d5839b3e69
https://doi.org/10.1038/s41598-020-77212-w

Effect of surface functional groups on the pH sensitivity in ion-sensitive field effect transistors

Autor: Nanki Hong, Bo Jin, Chanoh Park, Ki-Soo Jeong, Donghoon Kim, Jun-Sik Yoon, Jeong-Soo Lee

Publikováno v: 2016 IEEE 16th International Conference on Nanotechnology (IEEE-NANO).

For ion-sensitive devices with SiO 2 sensing membrane, the pH sensitivity response has been analyzed when additional functional groups are attached on the SiO 2 membrane. A modified Site-Binding model (SBM) and Gouy-Chapman-Stern (GCS) model are used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2b49854ed340e1362d278607bf0867b
https://doi.org/10.1109/nano.2016.7751374

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Autor: Brady Olsen, Marc K. Ting, Simon C. Johnson, Annie Chou, Dennis Wang, Monika Jelic, Zhongjun Zhou, Dillon Pruett, Eric C. Liao, Sarani Goswami, Mitsuhiro Tsuchiya, Ariana A. Rodriguez, Arieanna C. Anies, Theodor K. Bammler, Elroy H. An, Sylvia Sim, Diana N. Pak, Kristan K. Steffen, Juniper K. Pennypacker, Kim M. Pham, Christopher F. Bennett, Helen Vander Wende, Richard M. Moller, Bopharoth Ros, Tom Pollard, Richard P. Beyer, Mark A. McCormick, Winston Lo, Joe R. Delaney, Jennifer Schleit, Shannon Klum, Diana Kim, Anthony S. Castanza, Rachel B. Brem, Ki Soo Jeong, Benjamin L. Spector, Daniel B. Carr, Brian M. Wasko, K. Linnea Welton, Eric A. Westman, Donna Prunkard, Scott Tsuchiyama, Katie Kirkland, Amrita Solanky, Dilreet Rai, Shiena Enerio, Christopher J. Murakami, Manpreet K. Singh, Marissa Fletcher, Anna Shemorry, George L. Sutphin, Elijah D. Johnston, Molly A. Holmberg, Zhao Jun Peng, Lindsay A. Fox, Sean Higgins, Yousin Suh, Michael Lim, Dan Lockshon, Jin Kim, Jessica Hui, Erica D. Smith, Eunice Choi, Brian Muller, Xinguang Liu, Soumya Kotireddy, Nick Dang, Hillary Miller, Prarthana Pradeep, Di Hu, Brett Robison, Brian K. Kennedy, Matt Kaeberlein, Katie Snead, Michael Sage, Emily O. Kerr, Michael S. Lin, Umema Ahmed, Bie N. Tchao, Jonathan A. Oakes, Adrienne M. Wang

Publikováno v: Cell metabolism. 22(5)

SummaryMany genes that affect replicative lifespan (RLS) in the budding yeast Saccharomyces cerevisiae also affect aging in other organisms such as C. elegans and M. musculus. We performed a systematic analysis of yeast RLS in a set of 4,698 viable s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19253045f4261307bf82da7d1a0ad114
https://pubmed.ncbi.nlm.nih.gov/26456335

End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging

Autor: Benjamin L. Spector, Prarthana Pradeep, Jennifer Schleit, Sylvia Sim, Eric C. Liao, Jessica Hui, Helen Vander Wende, Richard M. Moller, Michael S. Lin, Winston Lo, Sean Higgins, Minnie Singh, Matt Kaeberlein, Jin R. Kim, Shannon Klum, Marissa Fletcher, Daniel B. Carr, Brian M. Wasko, Umema Ahmed, Dillon Pruett, Anthony S. Castanza, Tom Pollard, George L. Sutphin, Zhao J. Peng, Adrienne M. Wang, Brady Olsen, Alex Schuster, Annie Chou, Elroy H. An, Hillary Miller, Ki Soo Jeong, Christopher J. Murakami, Mollie Holmberg, Vanessa Ros, Dilreet Rai, Monika Jelic, Brian K. Kennedy, Joe R. Delaney

Publikováno v: FEMS yeast research. 13(3)

There is growing evidence that stochastic events play an important role in determining individual longevity. Studies in model organisms have demonstrated that genetically identical populations maintained under apparently equivalent environmental cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22076c9ff207ce5264946356eea35657
https://pubmed.ncbi.nlm.nih.gov/23336757