Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Ki-Bum Lee"'
Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions
Publikováno v:
Nano Convergence, Vol 11, Iss 1, Pp 1-36 (2024)
Abstract Central Nervous System (CNS) disorders represent a profound public health challenge that affects millions of people around the world. Diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and traumatic brain injury (TBI) e
Externí odkaz:
https://doaj.org/article/e3f8cda3f0174c22b1955352331087a3
Autor:
Sungkyu Lee, Jounghyun Yoo, Gunhyu Bae, Ramar Thangam, Jeongyun Heo, Jung Yeon Park, Honghwan Choi, Chowon Kim, Jusung An, Jungryun Kim, Kwang Rok Mun, Seungyong Shin, Kunyu Zhang, Pengchao Zhao, Yuri Kim, Nayeon Kang, Seong-Beom Han, Dahee Kim, Jiwon Yoon, Misun Kang, Jihwan Kim, Letao Yang, Solmaz Karamikamkar, Jinjoo Kim, Yangzhi Zhu, Alireza Hassani Najafabadi, Guosheng Song, Dong-Hwee Kim, Ki-Bum Lee, Soong Ju Oh, Hyun-Do Jung, Hyun-Cheol Song, Woo Young Jang, Liming Bian, Zhiqin Chu, Juyoung Yoon, Jong Seung Kim, Yu Shrike Zhang, Yongju Kim, Ho Seong Jang, Sehoon Kim, Heemin Kang
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 164-180 (2024)
Extracellular matrix (ECM) undergoes dynamic inflation that dynamically changes ligand nanospacing but has not been explored. Here we utilize ECM-mimicking photocontrolled supramolecular ligand-tunable Azo+ self-assembly composed of azobenzene deriva
Externí odkaz:
https://doaj.org/article/e001e36b311a4a63a46fd305d4aac455
Autor:
Hyeon‐Yeol Cho, Myungsik Yoo, Thanapat Pongkulapa, Hudifah Rabie, Alysson R. Muotri, Perry T. Yin, Jeong‐Woo Choi, Ki‐Bum Lee
Publikováno v:
Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)
Abstract The CRISPR‐Cas9 technology has the potential to revolutionize the treatment of various diseases, including Rett syndrome, by enabling the correction of genes or mutations in human patient cells. However, several challenges need to be addre
Externí odkaz:
https://doaj.org/article/7124b7eb05c34190b1e27d9c94807b25
Autor:
Jeffrey Luo, Anjani Darai, Thanapat Pongkulapa, Brian Conley, Letao Yang, Inbo Han, Ki-Bum Lee
Publikováno v:
Bioactive Materials, Vol 23, Iss , Pp 551-562 (2023)
Intervertebral disc (IVD) degeneration is a leading cause of back pain and precursor to more severe conditions, including disc herniation and spinal stenosis. While traditional growth factor therapies (e.g., TGFβ) are effective at transiently revers
Externí odkaz:
https://doaj.org/article/d4656383e47849709e69cb7ccb1353ac
Publikováno v:
Nano Convergence, Vol 9, Iss 1, Pp 1-31 (2022)
Abstract Immunotherapy has reached clinical success in the last decade, with the emergence of new and effective treatments such as checkpoint blockade therapy and CAR T-cell therapy that have drastically improved patient outcomes. Still, these therap
Externí odkaz:
https://doaj.org/article/11edc2c66ca64f0ca266c274fa7ba35a
Publikováno v:
Neurospine, Vol 20, Iss 2, Pp 449-450 (2023)
Externí odkaz:
https://doaj.org/article/ad2443e122364556af5cbd47c401d4b6
Autor:
Letao Yang, Brian M. Conley, Jinho Yoon, Christopher Rathnam, Thanapat Pongkulapa, Brandon Conklin, Yannan Hou, Ki-Bum Lee
Publikováno v:
Research, Vol 2022 (2022)
A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cell behavior in neurological disorders and accelerate the development of stem cell-based therapies. Nevertheless, high-
Externí odkaz:
https://doaj.org/article/ccc9306763d54332ac3950bdb19bf335
Autor:
Mohammad J. Hajipour, Amir Ata Saei, Edward D. Walker, Brian Conley, Yadollah Omidi, Ki‐Bum Lee, Morteza Mahmoudi
Publikováno v:
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Abstract The emergence of nanotechnology has created unprecedented hopes for addressing several unmet industrial and clinical issues, including the growing threat so‐termed “antibiotic resistance” in medicine. Over the last decade, nanotechnolo
Externí odkaz:
https://doaj.org/article/760fa47df7904e82be5e31f2cbe292c8
Autor:
Letao Yang, Sy-Tsong Dean Chueng, Ying Li, Misaal Patel, Christopher Rathnam, Gangotri Dey, Lu Wang, Li Cai, Ki-Bum Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The promise of stem cell therapy for treating central nervous system disease is limited by low stem cell transplantation survival rates and poorly controlled cell fate. Here, the authors develop a biodegradable nanoscaffold for spinal cord injury tha
Externí odkaz:
https://doaj.org/article/be9fc10d31f2457e96876bb1f1b4dff1
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Sensorineural hearing loss affects millions of people worldwide and is a growing concern in the aging population. Treatment using aminoglycoside antibiotics for infection and exposure to loud sounds contribute to the degeneration of cochlear hair cel
Externí odkaz:
https://doaj.org/article/9fc8134855e64e659018d249197d0c44