Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Ki Wung Chung"'
Autor:
Jeongwon Kim, Sugyeong Ha, Minjung Son, Doyeon Kim, Mi-Jeong Kim, Bumseok Kim, Donghwan Kim, Hae Young Chung, Ki Wung Chung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Toll-like receptor 7 (TLR7) is an endosomal TLR activated by single-stranded RNA, including endogenous microRNAs. Although TLR7 is known to promote inflammatory responses in pathophysiological conditions, its role in renal fibrosi
Externí odkaz:
https://doaj.org/article/2b9504b9e1ca4fa0921e5c62a3174905
Autor:
Jeongwon Kim, Jieun Lee, Dahye Yoon, Minjung Son, Mi-Jeong Kim, Sugyeong Ha, Doyeon Kim, Ji-an Yoo, Donghwan Kim, Hae Young Chung, Hyung Ryong Moon, Ki Wung Chung
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1947 (2023)
Chronic kidney disease (CKD) is a kidney structure and function abnormality. CKD development and progression are strongly influenced by oxidative stress and inflammatory responses, which can lead to tubulointerstitial fibrosis. Unfortunately, there a
Externí odkaz:
https://doaj.org/article/c2104f4e5bd74a75aa70f8887fa9d6eb
Autor:
Minjung Son, Ga Young Kim, Yejin Yang, Sugyeong Ha, Jeongwon Kim, Doyeon Kim, Hae Young Chung, Hyung Ryong Moon, Ki Wung Chung
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4882 (2023)
The peroxisome proliferator-activated receptor (PPAR) nuclear receptor has been an interesting target for the treatment of chronic diseases. Although the efficacy of PPAR pan agonists in several metabolic diseases has been well studied, the effect of
Externí odkaz:
https://doaj.org/article/78dc0b88041942e9a8de17cca616b659
Autor:
Seulah Lee, Yeon Ji Suh, Yujeong Lee, Seonguk Yang, Dong Geun Hong, Dinakaran Thirumalai, Seung-Cheol Chang, Ki Wung Chung, Young-Suk Jung, Hyung Ryong Moon, Hae Young Chung, Jaewon Lee
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1855 (2021)
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, and is caused by the death of dopamine neurons and neuroinflammation in the striatum and substantia nigra. Furthermore, the inflammatory response in PD is closely relat
Externí odkaz:
https://doaj.org/article/24f95c4684064d02b96f11579314de8f
Autor:
Ki Wung Chung
Publikováno v:
Cells, Vol 10, Iss 4, p 880 (2021)
During aging, body adiposity increases with changes in the metabolism of lipids and their metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity leads to various age-related diseases, including cardiovascular di
Externí odkaz:
https://doaj.org/article/43a919446ad0467ea40578f3cd701554
Autor:
Shizheng Huang, Jihwan Park, Chengxiang Qiu, Ki Wung Chung, Szu-Yuan Li, Yasemin Sirin, Seung Hyeok Han, Verdon Taylor, Ursula Zimber-Strobl, Katalin Susztak
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2005233 (2018)
While Notch signaling has been proposed to play a key role in fibrosis, the direct molecular pathways targeted by Notch signaling and the precise ligand and receptor pair that are responsible for kidney disease remain poorly defined. In this study, w
Externí odkaz:
https://doaj.org/article/9e2933f335bb4d558b23529c6dbb299c
Autor:
Eun Ji Jang, Hyoung Oh Jeong, Daeui Park, Dae Hyun Kim, Yeon Ja Choi, Ki Wung Chung, Min Hi Park, Byung Pal Yu, Hae Young Chung
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0129244 (2015)
4-Hydroxynonenal (4-HNE), a major end product of lipid peroxidation, is highly reactive and involved in various cellular processes, such as inflammatory signaling. However, to date, the mechanistic roles of 4-HNE in inflammatory signaling related to
Externí odkaz:
https://doaj.org/article/7fbb64f4d74a432ca7a8b2ca21ed366a
Autor:
Kyung Kyun Noh, Ki Wung Chung, Yeon Ja Choi, Min Hi Park, Eun Ji Jang, Chan Hum Park, Changshin Yoon, Nam Deuk Kim, Mi Kyung Kim, Hae Young Chung
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102947 (2014)
Skeletal muscle atrophy results from various conditions including high levels of glucocorticoids, and β-hydroxy β-methylbutyrate (HMB; a metabolite of leucine) is a potent therapeutical supplement used to treat various muscle disorders. Recent stud
Externí odkaz:
https://doaj.org/article/e9ed6be5cd524e4bab26339b6660c36d
Autor:
Dae Hyun Kim, Min Hi Park, Yeon Ja Choi, Ki Wung Chung, Chan Hum Park, Eun Ji Jang, Hye Jin An, Byung Pal Yu, Hae Young Chung
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59316 (2013)
Heptadecane is a volatile component of Spirulina platensis, and blocks the de novo synthesis of fatty acids and ameliorates several oxidative stress-related diseases. In a redox state disrupted by oxidative stress, pro-inflammatory genes are upregula
Externí odkaz:
https://doaj.org/article/bb4825b8de1b48c38521a196359e2782
Autor:
Min Hi Park, Ji Young Park, Hye Jin Lee, Dae Hyun Kim, Ki Wung Chung, Daeui Park, Hyoung Oh Jeong, Hye Rim Kim, Chan Hum Park, So Ra Kim, Pusoon Chun, Youngjoo Byun, Hyung Ryong Moon, Hae Young Chung
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76820 (2013)
Ultraviolet B (UVB; 290~320nm) irradiation-induced lipid peroxidation induces inflammatory responses that lead to skin wrinkle formation and epidermal thickening. Peroxisome proliferator-activated receptor (PPAR) α/γ dual agonists have the potentia
Externí odkaz:
https://doaj.org/article/6f7a9c8b1433415680b67906d6d8f544