Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Ki Soon Shin"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract This study explores the behavioral effects of modulating CaMKII-positive (CaMKII+) neurons in the posterior hypothalamus (PH). Utilizing a chemogenetic approach in mice, we discovered that the activation of CaMKII + neurons within the PH is
Externí odkaz:
https://doaj.org/article/b9735e51d73b414cb312744a66adb2f2
Publikováno v:
Animal Cells and Systems, Vol 22, Iss 3, Pp 165-171 (2018)
The medial habenula (MHb) plays an important role in nicotine-related behaviors, such as aversion and withdrawal. The MHb is composed of distinct subregions with unique neurotransmitter expression and neuronal connectivity. Here, we showed that nicot
Externí odkaz:
https://doaj.org/article/619cb238f2ac4a98a52a97a825b4dca8
Publikováno v:
Biochemical and Biophysical Research Communications. 627:97-102
A nuclear serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) is a critical regulator of development and DNA damage response. HIPK2 can induce apoptosis under cellular stress conditions and thus its protein level is maintained lo
Publikováno v:
Biochemical and biophysical research communications. 637
Recently, we reported that auditory fear conditioning leads to the presynaptic potentiation at lateral amygdala to basal amygdala (LA-BA) synapses that shares the mechanism with high-frequency stimulation (HFS)-induced long-term potentiation (LTP) ex
Autor:
Ki Soon Shin, Tae-Ik Choi, Yong-Min Kim, Insop Shim, Yunhee Kim Kwon, Sun Ae Moon, Jae Hwan Ryu, Soonje Lee, Dae-Yeul Yu, Bing Han, Cheol-Hee Kim, In Seon Bak, Hyang-Sook Hoe, Cheil Moon, Hyun-ju Lee
Publikováno v:
Molecular Psychiatry. 26:3737-3750
Guanine nucleotide binding protein (G protein) gamma 8 (Gng8) is a subunit of G proteins and expressed in the medial habenula (MHb) and interpeduncular nucleus (IPN). Recent studies have demonstrated that Gng8 is involved in brain development; howeve
Publikováno v:
Biochemical and Biophysical Research Communications. 526:986-992
PARP-1 is a multifunctional enzyme that regulates DNA repair, chromatin remodeling, inflammation and cell survival. Our previous study revealed that PARP-1 is required for maintaining normal level of neural stem cell proliferation. In the present stu
Autor:
Chang-Hwan Park, Jong Hoon Ryu, Ki Soon Shin, Shin Jung Kang, Soonje Lee, Jee Hyun Yi, Seokheon Hong
Publikováno v:
Cell Death and Disease, Vol 10, Iss 12, Pp 1-16 (2019)
Cell Death & Disease
Cell Death & Disease
In the current study we present evidence suggesting that PARP-1 regulates neurogenesis and its deficiency may result in schizophrenia-like behavioral deficits in mice. PARP-1 knockout neural stem cells exhibited a marked upregulation of embryonic ste
Autor:
Kyuhyun Choi, Soonje Lee, Shin Jung Kang, Changsu Woo, Ki Soon Shin, Kyungjoon Park, Jee Hyun Yi
Publikováno v:
Biochemical and biophysical research communications. 584
The lateral amygdala (LA) is a main sensory input site from the cortical and thalamic regions. In turn, LA glutamatergic pyramidal neurons strongly project to the basal amygdala (BA). Although it is well known that auditory fear conditioning involves
Publikováno v:
Animal cells and systems
Animal Cells and Systems, Vol 22, Iss 3, Pp 165-171 (2018)
Animal Cells and Systems, Vol 22, Iss 3, Pp 165-171 (2018)
The medial habenula (MHb) plays an important role in nicotine-related behaviors, such as aversion and withdrawal. The MHb is composed of distinct subregions with unique neurotransmitter expression and neuronal connectivity. Here, we showed that nicot
Publikováno v:
Biochemical and biophysical research communications. 515(3)
The ventral subiculum (vSub) is the major output structure of the hippocampus and serves as a main limbic region in mediating the brain's response to stress. Previously, we reported that there are three subtypes of vSub neurons based on their firing