Time-dynamic pulse modulation of spinal cord stimulation reduces mechanical hypersensitivity and spontaneous pain in rats

Autor: Muhammad M. Edhi, Lonne Heijmans, Kevin N. Vanent, Kiernan Bloye, Amanda Baanante, Ki-Soo Jeong, Jason Leung, Changfang Zhu, Rosana Esteller, Carl Y. Saab

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

Abstract Enhancing the efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and dependence on opioids. Present SCS therapies are characterized by the delivery of constant stimulation in the form of trains of ton

Externí odkaz: https://doaj.org/article/13407e805180457ca6392ef3cb28ac16

Time-dynamic pulse modulation of spinal cord stimulation reduces mechanical hypersensitivity and spontaneous pain in rats

Autor: Carl Y. Saab, Jason W. Leung, Muhammad M. Edhi, Kiernan Bloye, Amanda Baanante, Rosana Esteller, Ki-Soo Jeong, Kevin N. Vanent, Changfang Zhu, Lonne Heijmans

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1):20358. Nature Publishing Group
Scientific Reports

Enhancing the efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and dependence on opioids. Present SCS therapies are characterized by the delivery of constant stimulation in the form of trains of tonic pulses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d4580021a326aea31690d5839b3e69
https://doi.org/10.1038/s41598-020-77212-w

Effect of surface functional groups on the pH sensitivity in ion-sensitive field effect transistors

Autor: Nanki Hong, Bo Jin, Chanoh Park, Ki-Soo Jeong, Donghoon Kim, Jun-Sik Yoon, Jeong-Soo Lee

Publikováno v: 2016 IEEE 16th International Conference on Nanotechnology (IEEE-NANO).

For ion-sensitive devices with SiO 2 sensing membrane, the pH sensitivity response has been analyzed when additional functional groups are attached on the SiO 2 membrane. A modified Site-Binding model (SBM) and Gouy-Chapman-Stern (GCS) model are used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2b49854ed340e1362d278607bf0867b
https://doi.org/10.1109/nano.2016.7751374

A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Autor: Brady Olsen, Marc K. Ting, Simon C. Johnson, Annie Chou, Dennis Wang, Monika Jelic, Zhongjun Zhou, Dillon Pruett, Eric C. Liao, Sarani Goswami, Mitsuhiro Tsuchiya, Ariana A. Rodriguez, Arieanna C. Anies, Theodor K. Bammler, Elroy H. An, Sylvia Sim, Diana N. Pak, Kristan K. Steffen, Juniper K. Pennypacker, Kim M. Pham, Christopher F. Bennett, Helen Vander Wende, Richard M. Moller, Bopharoth Ros, Tom Pollard, Richard P. Beyer, Mark A. McCormick, Winston Lo, Joe R. Delaney, Jennifer Schleit, Shannon Klum, Diana Kim, Anthony S. Castanza, Rachel B. Brem, Ki Soo Jeong, Benjamin L. Spector, Daniel B. Carr, Brian M. Wasko, K. Linnea Welton, Eric A. Westman, Donna Prunkard, Scott Tsuchiyama, Katie Kirkland, Amrita Solanky, Dilreet Rai, Shiena Enerio, Christopher J. Murakami, Manpreet K. Singh, Marissa Fletcher, Anna Shemorry, George L. Sutphin, Elijah D. Johnston, Molly A. Holmberg, Zhao Jun Peng, Lindsay A. Fox, Sean Higgins, Yousin Suh, Michael Lim, Dan Lockshon, Jin Kim, Jessica Hui, Erica D. Smith, Eunice Choi, Brian Muller, Xinguang Liu, Soumya Kotireddy, Nick Dang, Hillary Miller, Prarthana Pradeep, Di Hu, Brett Robison, Brian K. Kennedy, Matt Kaeberlein, Katie Snead, Michael Sage, Emily O. Kerr, Michael S. Lin, Umema Ahmed, Bie N. Tchao, Jonathan A. Oakes, Adrienne M. Wang

Publikováno v: Cell metabolism. 22(5)

SummaryMany genes that affect replicative lifespan (RLS) in the budding yeast Saccharomyces cerevisiae also affect aging in other organisms such as C. elegans and M. musculus. We performed a systematic analysis of yeast RLS in a set of 4,698 viable s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19253045f4261307bf82da7d1a0ad114
https://pubmed.ncbi.nlm.nih.gov/26456335

Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae

Autor: Adrienne M. Wang, Brady Olsen, Alex Schuster, Sean Higgins, Minnie Singh, Monika Jelic, Sarani Goswami, Anthony S. Castanza, Marissa Fletcher, Elroy H. An, Shannon Klum, Tom Pollard, Joe R. Delaney, Jessica Hui, Dilreet Rai, Jennifer Schleit, Eric C. Liao, Benjamin L. Spector, Dillon Pruett, Prarthana Pradeep, Hillary Miller, Annie Chou, Helen Vander Wende, Michael S. Lin, Richard M. Moller, Winston Lo, Mollie Holmberg, Jin R. Kim, Vanessa Ros, Daniel B. Carr, Brian M. Wasko, Ki Soo Jeong, George L. Sutphin, Christopher J. Murakami, Zhao J. Peng, Matt Kaeberlein

Chronological aging of budding yeast cells results in a reduction in subsequent replicative life span through unknown mechanisms. Here we show that dietary restriction during chronological aging delays the reduction in subsequent replicative life spa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49a2fc5b50ec921b49e1757f2bc3c77
https://europepmc.org/articles/PMC3604125/