Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ki Hwan Chang"'
Autor:
Seong A. Kim, Seohyun Kim, Gi Beom Kim, Jiyoung Goo, Nayeon Kim, Yeram Lee, Gi-Hoon Nam, Seungho Lim, Taeerk Kim, Ki Hwan Chang, Tae Gyu Lee, In-San Kim, Eun Jung Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6123 (2022)
The SARS-CoV-2 pandemic has created a global public crisis and heavily affected personal lives, healthcare systems, and global economies. Virus variants are continuously emerging, and, thus, the pandemic has been ongoing for over two years. Vaccines
Externí odkaz:
https://doaj.org/article/74b005bddf3446869f67fad6b07f2ed1
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Supplementary Figure 2. The EGFR-GC1118 interaction is not disrupted by excess amounts of high- or low-affinity EGFR ligands. The indicated colorectal cancer cell lines were pre-incubated with 0.1 ug/ml of cetuximab or GC1118 for 2 h prior to the add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725f884ad46d30da06419018eeec1d81
https://doi.org/10.1158/1535-7163.22503043
https://doi.org/10.1158/1535-7163.22503043
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Supplementary Figure 1. Kinetic binding interactions between GC1118 and EGFR as analyzed by SPR. SPR sensorgrams were obtained from injections of (A) GC1118 or (B) cetuximab over an EGFR-immobilized surface at a flow rate of 30 µl/min. The results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c649a0a3bacb6dfcc106d8d9e853e5
https://doi.org/10.1158/1535-7163.22503046
https://doi.org/10.1158/1535-7163.22503046
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Supplementary Table 1. X-ray data collection and refinement statistics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7dae88c660f0113a5814ad11b8dd2f
https://doi.org/10.1158/1535-7163.22503037.v1
https://doi.org/10.1158/1535-7163.22503037.v1
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Surface plasmon resonance (SPR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b986e8555bae1ac03b9cf184edfa9b
https://doi.org/10.1158/1535-7163.22503040
https://doi.org/10.1158/1535-7163.22503040
Autor:
James Palacino, Pedro Lee, Hangyeol Jeong, Yeonjoon Kim, Yoojin Song, Uttapol Permpoon, Wesley Wong, Chen Bai, Nathan Fishkin, Khuloud Takrouri, Eunjin Yu, Yong Yi, Anna Skaletskaya, Ki-Hwan Chang, Min-Soo Kim, Da-Yeong Kim, Dong-Ki Choi, Peter U Park
Publikováno v:
Blood. 140:3061-3062
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a269d96e6caa27fb8cac688926936eb0
https://doi.org/10.1182/blood-2022-168936
https://doi.org/10.1182/blood-2022-168936
Autor:
James Palacino, Chen Bai, Yong Yi, Anna Skaletskaya, Khuloud Takrouri, Wesley Wong, Min-Soo Kim, Dong-Ki Choi, Da-Young Kim, Yeonhee Yang, Jiae Kook, Pedro Lee, Hangyeol Jeong, Sang-Mi Jee, Jiyun Park, Ki-Hwan Chang, Nathan Fishkin, Peter U. Park
Publikováno v:
Cancer Research. 82:3933-3933
Targeted protein degradation (TPD) molecules, including IMiD-based molecular glues and heterobifunctional degraders have expanded the breadth of therapeutic options through both their catalytic mechanism of action and ability to degrade previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3721e0df43cd095effb959ab01db3fd9
https://doi.org/10.1158/1538-7445.am2022-3933
https://doi.org/10.1158/1538-7445.am2022-3933
Autor:
Sang Gu Yeo, Jong Hyun Kim, Se-Ho Kim, Dong-Hyung Cho, Yong Won Shin, Ki Hwan Chang, Gwang Won Hong, Myoung Don Oh, Youngmee Jee
Publikováno v:
Journal of microbiology and biotechnology. 29(4)
Although smallpox was eradicated in 1980, it is still considered a potential agent of biowarfare and bioterrorism. Smallpox has the potential for high mortality rates along with a major public health impact, eventually causing public panic and social
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432699d09857c8019af2437aa8311523
https://pubmed.ncbi.nlm.nih.gov/30856707
https://pubmed.ncbi.nlm.nih.gov/30856707
Autor:
Jiho Yoo, Min Soo Kim, Yeup Yoon, Tae Wook Park, Jonghwa Won, Yangmi Lim, Kwang Won Hong, Jae-Chul Lee, Yeon Gil Kim, Minkyu Hur, Do-Hyun Nam, Shi Nai Lee, Eun-Hee Lee, Se-Ho Kim, Donggeon Kim, Kyuhyun Lee, Hyung Suk Hur, Kuglae Kim, Yingjin Kang, Ki Hwan Chang, Hyun Soo Cho, Heekyoung Yang
Publikováno v:
Molecular Cancer Therapeutics. 15:251-263
The EGFR-targeted monoclonal antibodies are a valid therapeutic strategy for patients with metastatic colorectal cancer (mCRC). However, only a small subset of mCRC patients has therapeutic benefits and there are high demands for EGFR therapeutics wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d320e3c8310b2bba6b7c84a297fe0e
https://doi.org/10.1158/1535-7163.mct-15-0679
https://doi.org/10.1158/1535-7163.mct-15-0679
Autor:
Kwang-Won Hong, Pan-Kyung Kim, Ki-Tae Bong, Jin-Seol Choi, Minyoung So, Jie-Young Park, Ki-Hwan Chang, Se-Ho Kim, Kyung-Hwan Ryoo, Yong-Won Shin
Publikováno v:
Antiviral Research. 75:113-120
Hepatitis B virus (HBV) is one of the main pathogens responsible for hepatitis and hepatocellular carcinoma. Human plasma-derived Hepatitis B immune globulin (HBIG) is being used for prophylactic and liver transplantation currently. However, it may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a92252ddf65de0cec04a2c787877f5
https://doi.org/10.1016/j.antiviral.2007.01.005
https://doi.org/10.1016/j.antiviral.2007.01.005