Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ki Bum Um"'
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3283 (2023)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social communication and social interaction, restricted and repetitive behavior, and interests. The core symptoms of ASD are associated with deficits in
Externí odkaz:
https://doaj.org/article/c0aeacebe00247e2bdaf801b7ba21240
Autor:
Ki Bum Um, Suyun Hahn, So Woon Kim, Yoon Je Lee, Lutz Birnbaumer, Hyun Jin Kim, Myoung Kyu Park
Publikováno v:
eLife, Vol 10 (2021)
Midbrain dopamine (DA) neurons are slow pacemakers that maintain extracellular DA levels. During the interspike intervals, subthreshold slow depolarization underlies autonomous pacemaking and determines its rate. However, the ion channels that determ
Externí odkaz:
https://doaj.org/article/348ce7b560f8410a91decb1ac05e89fb
Publikováno v:
Korean Journal of Physiology & Pharmacology; Mar2024, Vol. 28 Issue 2, p165-181, 17p
Publikováno v:
The Journal of physiologyReferences.
In multipolar nigral dopamine (DA) neurons, the highly excitable proximal dendritic compartments (PDCs) and two Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27f24436c5018ed41bb31f1d59894a4
https://pubmed.ncbi.nlm.nih.gov/36398712
https://pubmed.ncbi.nlm.nih.gov/36398712
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: NALCN is a Na(+) leak, GPCR‐activated channel that regulates the resting membrane potential and neuronal excitability. Despite numerous possible roles for NALCN in both normal physiology and disease processes, lack of specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3711b8f578d16dc0357de7535da060f3
https://doi.org/10.1111/bph.15104
https://doi.org/10.1111/bph.15104
Autor:
Lutz Birnbaumer, Yoon Je Lee, Myoung Kyu Park, Ki Bum Um, Hyunjin Kim, Suyun Hahn, So Woon Kim
Midbrain dopamine (DA) neurons are slow pacemakers that maintain extracellular DA levels. During the interspike intervals, subthreshold slow depolarization underlies autonomous pacemaking and determines its rate. However, the ion channels that determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a340080d9453e941027f15bfaf45fc
https://doi.org/10.1101/2021.06.03.447013
https://doi.org/10.1101/2021.06.03.447013
Coexistence of glutamatergic spine synapses and shaft synapses in substantia nigra dopamine neurons.
Autor:
Miae Jang1,2, Ki Bum Um1,2, Jinyoung Jang1,2, Hyun Jin Kim1,2, Hana Cho1,2, Sungkwon Chung1,2, Myoung Kyu Park1,2 mkpark@skku.edu
Publikováno v:
Scientific Reports. 10/9/2015, p1-16. 16p.
Autor:
Myoung Kyu Park, Ki Bum Um, Miae Jang, Shin Hye Kim, Jinyoung Jang, Hyun-Jin Kim, Hana Cho, Sungkwon Chung
Publikováno v:
The Journal of Physiology. 592:2829-2844
Midbrain dopamine (DA) neurons are slow intrinsic pacemakers that require the elaborate composition of many ion channels in the somatodendritic compartments. Understanding the major determinants of the spontaneous firing rate (SFR) of midbrain DA neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15ab9c5c362731c26b3a4391acdd7a7
https://doi.org/10.1113/jphysiol.2014.275032
https://doi.org/10.1113/jphysiol.2014.275032
Autor:
Hyeshin Yoon, Byeong Mo Kim, Ki Bum Um, Gibok Lee, Hong-Il Kim, Jaekyoung Son, Chang-Soo Lee, Taek-In Oh, Hackyoung Kim, Ji-Hong Lim, Young Jun Kim
Publikováno v:
Biochemical and biophysical research communications. 470(1)
USP7 is a deubiquitinating enzyme that involves the ubiquitin proteasome system (UPS) to maintain regulation of protein synthesis and degradation. The well-known substrate of USP7 is the Mdm2-p53 complex. In fact, several studies have reported that f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc136e15080d7251f66ce273ebcf7e3b
https://pubmed.ncbi.nlm.nih.gov/26768359
https://pubmed.ncbi.nlm.nih.gov/26768359
Autor:
Sungkwon Chung, Jinyoung Jang, Hyun-Jin Kim, Shin Hye Kim, Yun Kyung Kang, Miae Jang, Myoung Kyu Park, Ki Bum Um
Publikováno v:
Journal of Neurochemistry. 116:966-974
J. Neurochem. (2011) 116, 966–974. Abstract Dopamine (DA) receptors generate many cellular signals and play various roles in locomotion, motivation, hormone production, and drug abuse. According to the location and expression types of the receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2d13e1d56c190c02af07c91cea71ef5
https://doi.org/10.1111/j.1471-4159.2010.07107.x
https://doi.org/10.1111/j.1471-4159.2010.07107.x